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Research Article
Comparison of Dexamethasone with Local Anaesthetic Versus Local Anaesthetic for Laparoscopic Port Infiltration to Assess Effectiveness as Post-operative Analgesia
Ariful Hoque, Shamima Nasrin Shadia and Moazzem Hossain*
DOI: 10.31031/NRS.2022.10.000740
Abstract
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Full-Text
e-Pub
Early postoperative pain remains the most prevalent complaint after any surgery. Beside conventional IV
analgesic medications, subcutanious infiltration has been established as a reliable pain relief technique.
Addition of dexamethasone to local anaesthetic (example: bupivacaine, lidocaine) can also be used as
it has some beneficial effect than use of bupivacaine only. The objectives of this study to evaluate the
duration of analgesic effects of dexamethasone with local anaesthetic as compared to local anaesthetic
in post operative patient. This Randomized controlled trial study was conducted among 60 patients who
underwent Laparoscopic cholecystectomy. This study was conducted from January,2019 to June,2019.
All patients who underwent laparoscopic cholecystectomy surgery were selec.....
Case Report
Homozygous INPP5E Mutation Associated Joubert Syndrome with Retinitis Pigmentosa A Case Report
Natalie Huang*and Amirfarbod Yazdanyar
DOI: 10.31031/MSOR.2022.03.000564
Purpose: To present a case with INPP5E mutation associated with Joubert syndrome and retinitis
pigmentosa (RP).
Methods: A 11-year-old girl presented with progressive vision loss, lack of coordination, and muscular
weakness. Vision acuity was 20/60 bilaterally. Dilated fundus exam revealed temporal disc pallor,
retinal pigmentary epithelial mottling and atrophy, and diffuse white specks. Fundus autofluorescence
showed diffuse peripheral hypo autofluorescence and a ring of hyper autofluorescence in the macula.
Electroretinography showed decreased cone and rod responses.
Results: Genetic test was positive for INPP5E c.1073C>T (p. Pro358Leu) homozygous mutation.
Conclusions and Importance: INPP5E is one of many genes contribute to Joubert syndrome. A novel
homozygous mutation in INPP.....
Review Article
Homozygous INPP5E Mutation Associated Joubert Syndrome with Retinitis PigmentosaA Case Report
DOI: 10.31031/EME.2022.04.000585
Micromachining is the technique used to fabricate 2D or 3 D structures on metals in range of micron level.
There are different techniques exist in industry for manufacturing the micro components. The MicroElectromechanical Systems (MEMS) are categorized such as photo lithography, wet and dry etching,
Fusion bonding, LIGA and laser micromachining. On the other hand, due to technological growth and
increased application of non-silicon-based materials in industry, Non-MEMS based techniques such as
Electrochemical Machining (ECM), Electro Discharge Machining (EDM), injection moulding, stamping and
extrusion employs effectively. This development in current manufacturing trend is generally recognized
that micro manufacturing. The current trend headed for the miniaturizations and micromachi.....
Opinion
Curative Patient-Specific Approach of Achalasia
DOI: 10.31031/ACAM.2022.07.000658
Achalasia is a chronic disease and all current treatments are in the palliative setting,
focusing on decreasing the outflow resistance of the esophagogastric junction [1]. This
relatively rare disorder is due to primary motor disfunction, characterized by the absence
of relaxations of the Lower Esophageal Sphincter (LES) and peristalsis along the esophagus
[1]. Up to 50% of patients with achalasia experience heartburn, dysphagia, and weight loss.
Regurgitation of food causes hoarseness and pneumonia. The exact etiology of this condition
is unknown; however viral, autoimmune triggers, and neurodegenerative diseases are often
afflicted to its presentation
Review Article
Improving the Accuracy of a Widely used Approximation for Computing the Faddeyeva and Voigt Functions
We present a simple remedy for the loss-of-accuracy problem, near the real axis, in a widely used
algorithm for the calculation of the Faddeyeva and Voigt functions. The reformed routine maintains the
claimed accuracy of the algorithm over a wide and fine grid that covers all the domain of the real part, x, of the complex input variable, z=x+iy, and values for the imaginary part in the range y∊[10-30, 1030]
Mini Review
Diversity of Phytochemical Composition of the Content of Cranberry Fruits (Vaccinium Macrocarpon L., Ericaceae) Depending on Growing Regions
DOI: 10.31031/ACAM.2022.07.000657
This work is devoted to scientific research carried out to investigate the content of cranberry fruits
(Vaccinium macrocarpon L., Ericaceae). To evaluate the influence of composition on anti-inflammatory
activity, cranberry fruits were collected from eight Serbia growing regions. Eight extracts from these
fruits were prepared. Extracts were analyzed for phytochemical composition and evaluated for their
anti-inflammatory effects in human monocytes (THP-1 cells). All were able to reduce Lipopolysaccharide
(LPS) -induced production of pro-inflammatory cytokine interleukin 6 (IL-6) at 50µg/mL, with inhibition
ranging between 10.09-42.7%. The research results show phytochemicals present in varying quantities
in cranberry fruits a role in the anti-inflammatory effects of cranberry extrac.....
Opinion
Human Microbiota, Functional Biodiversity and Agroecological Designs: In Search of a Healthy Diet
The modern diet is vastly different from that of our Paleolithic ancestors, who had an
annual base of some 500 different plants, whereas ours has fewer than 50; they ate their
food raw and often fermented, while we preserve, dry and cook our food, processes known to
destroy many sensitive nutrients and antioxidants. This may be the reason why we are now
seeing an increase in various atopic diseases, infections and so-called Western diseases [1].
The intestinal ecosystem is a complex environment in which dynamic and reciprocal
interactions occur between the epithelium, the immune system and the local microbiota [2].
Likewise, the concept of a nutrient as any assimilable substance contained in food, which
allows the body to obtain energy, build and repair tissues and regulate metabol.....
Mini Review
The Applications of Protein Nanomaterials in Cancer Therapies
Linjuan Wang, Tingting Tang, Kaiyue Zuo, Xinjie Zhu* and Wu Zhong*
DOI: 10.31031/NACS.2022.07.000658
Cancer serves as one of the main causes of death in global world, which has attracted tremendous
attention due to high morbidities and mortalities. Currently, the traditional chemotherapies are still
facing serious challenges, such as multidrug resistance, relapse and adverse events. What’s more, these
risk factors will affect therapeutic efficacy. With the development of nanotechnologies, it provides great
potential for cancer therapies ranging from non-targeting protein nanomaterials to nanobody with
specific antigen recognition. In this mini review, we will mainly discuss the progress and approaches of
protein nanomaterials being used to improve cancer therapeutic efficacy
Review Article
Deformation Behaviour and in Microstructural Analysis of Titanium alloy
Boopathi R*, Senthur R, Raajkumar M, Shabharrish S and Saravanan S
DOI: 10.31031/RDMS.2022.17.000910
The present study deals with the warm temperature deformation behavior of the titanium (Ti-6Al-4V)
alloy throughout investigating the flow behavior and the correlated microstructure evolutions. Toward
this end, the hot compression tests were conducted at different temperatures and strain rate. Titanium
is a low-density element that can be highly strengthened by alloying and deformation processing.
Titanium is nonmagnetic and has good heat transfer properties. Its co-efficient of thermal expansion
is somewhat lower than half that of aluminum. The titanium materials, in a relatively short time, have
become backbone materials for the aerospace, energy, and chemical industries. The combination of high
strength-to-weight ratio, excellent mechanical properties, and corrosion resistance ma.....
Mini Review
Cork Oak Forests, Sustainable Forestry
This article gives a succinct description of cork oak and cork: it discusses their biodiversity, origin and
gives some data on surface areas and cork production in the world. The key issues for maintaining these
ecosystems are detailed. It concludes with the benefits of using cork and continuing to manage cork oak
forests sustainably
Opinion
Genetic Approaches for Sustainable Production of Onion Against Abiotic Stresses
Usman KC*, Zahide NOG and Ali FG
Onion (Allium cepa L.) is the main bulbous crop cultivated commercially globally. It is the main condiment
crop and consumed second in number after tomato. Contrarily, abiotic stresses are impacting the growth,
yield, and quality of the onion. Single stress is significantly resulting in poor yield, whereas combined
abiotic stresses are resulting in devastating yield losses under natural conditions. Additionally, it is predicted the water scarcity is increasing on yearly basis and it also triggers other abiotic stresses. Therefore,
it is the major threat to onion production, and it is predicted to cause devastating yield losses. Modern
genetic approaches have broadened our horizon to develop stress resilient vegetables to cope with future
climatic changes to ensure food security. Seve.....
Mini Review
The Bumpy Fecundation-Placental Site Trophoblastic Tumour
DOI: 10.31031/TTEH.2022.03.000566
Placental site trophoblastic tumour is an infrequently discerned gestational trophoblastic neoplasm
emerging from placental implantation site. Tumefaction may emerge subsequent to gestation at term,
spontaneous abortion or a molar pregnancy. Of obscure aetiology, the neoplasm arises due to neoplastic
transformation of cytotrophoblastic cells wherein transformed cells differentiate towards intermediate
trophoblast. Clinically, irregular vaginal bleeding, menorrhagia, abnormal uterine bleeding, amenorrhea
or an enlarged uterus are observed. The infiltrative neoplasm is composed of sheets and aggregates of
enlarged, spherical or polyhedral, mononuclear intermediate trophoblastic cells imbued with abundant
amphophilic, eosinophilic or clear cytoplasm with irregular cytoplasmic perimeter.....
Opinion
Patient Relation with Doctor & Telemedicine and Nanomedicine
Donatella Lippi and Mario M D Elios*
DOI: 10.31031/TTEH.2022.03.000567
The whole history of medical technology shows the effort to produce ever smaller and
more manageable instruments. From the thermometer to the sphygmomanometer, from the
scale to the ECG machines, the technique has evolved, creating devices that are increasingly
suitable for clinical use and more manageable, and improving their reliability [1]. Today, this
trend has further specialized, constructing tools that can significantly affect clinical practice,
also transforming the doctor-patient relationship. In these last years, this miniaturizing
process has produced hand-free wearable devices, for instance, that can also be worn as
accessories, embedded in clothing, implanted in the user’s body, or even tattooed on the skin
Research Article
Assessment of Mechanical Strength of Ecofriendly Slag-Concrete and Metakaolin in an Aggressive Environment
Abiola OS*, Igba UT, Odunfa SO, Adetiolye A, Gbadewole OA and Osinowo AA
DOI: 10.31031/RDMS.2022.17.000909
This paper presents an assessment of mechanical strength of slag-concrete with partially replacing
cement with 0, 10, 20, and 30% metakaolin (MK) for a targeted strength of 35MPa at 28-day curing. The
compressive, split tensile and flexural strength of the concrete were examined in line with appropriate
specifications. The durability was evaluated by exposing the concrete specimens to sodium sulphate and
sodium chloride for 7, 28, 56, and 90 days and measure the loss in compressive strength. The mix design
with water-cement ratio of 0.5 is 1:1.21:2.89 (cement: sand: coarse slag). The targeted compressive
strength was met by all the percentages of metakaolin though the strength decreases with increase
in percentage of metakaolin added. The MK10 has the highest value for compressive, .....
Mini Review
Status of Endangered Tree species in Savannah Landscape, Nigeria: Causes and Restoration possibilities
Savanna biome is well known with high temperature, low humidity, and loose sandy soil. Among common
species in this area are azardirachta indica, dalbergia sissoo, phoenix dactylifera, Balanities eagyptiaca
and Eucalyptus camadulensis. These tree species have great potentials in Northern Nigeria in terms of
adaptability, economics, and environmental values. Recent research proof that the tree species such as
Adansonia digitata, tamarindus indica, parkia biglobosa, vitellaria paradoxa, hyphaene thebaica, faidherbia
albida, khaya senegalensis and Borassus aethiopica were the most commonly exploited and endangered
economic tree species which were used for different purposes. Some of these species had been used for
afforestation programs and research purposes. Among the causes of specie.....
Opinion
Fascinating Stories of Prion Studies: From the Bench to Pharmaceuticals
DOI: 10.31031/CRAS.2022.02.000531
Since the discovery of prion, continuous works have been undergone to uncover the true
picture of prion protein and prion disease molecular mechanism. Several attempts were
made to define the structure of prion protein and its association with prion diseases. X-ray,
solution NMR, and other high-resolution techniques were employed to reveal the structure of
the infective form of PrP. Although the putative PrPC structure of many species was reported,
the absence of a crystallized form of PrPSc makes the understanding of the prion disease
mechanism difficult. Recently, a group of researchers mimicked cellular PrP and discovered
artificial recombinant human PrP that has infectivity potency [1,2]. This artificial rec.hPrP
is expressed in bacteria in a reaction that seeded brain-derived .....
Research Article
A Light-Weight Low-Speed Stirrer for Proper Mixing of Fertilizer and Water in a SmallScale Automated Irrigation System
DOI: 10.31031/EME.2022.04.000584
Proper mixing of fertilizer and water is a serious problem in a small-scale automated irrigated land
observed during a visit to a farm in Kumpung Lumapas, Brunei. It is usually done manually and takes
a lot of effort and time. An automatic low-speed and a lightweight stirring mechanism was designed,
fabricated and installed to solve this problem using power from the same electric motor which are used
to run the pump. The high speed of the rotating shaft from the existing pump was utilized and connected
to a belt-pulley system to reduce its speed. The motor and pump unit were separated from direct coupling
system and arranged in parallel with each other. Then, the shaft of the big pulley was linked to a speed
reduction gearbox to further reduce the speed of the Polyvinyl Chloride (PV.....
Research Article
Can Gestational Anti-Diabetic Plants Using in Cameroon Manage Preeclampsia?
Tsabang Nole* and Tsambang Djeufack Wilfried Lionel
DOI: 10.31031/IOD.2022.06.000626
Preeclampsia is a persistent hypertensive gestational disease that might happen during pregnancy
(antepartum), during delivery (intrapartum) or after childbirth (postpartum). It is clinically characterized
by maternal high hypertension (>140/90mmHg systolic/diastolic blood pressure) and massive proteinuria
(>300mg/24h). Severe cases are manifested by the development of comorbidities such as eclampsia,
liver damage, edema and scattered vascular coagulation in mother and the complications in the fetus
like fetal growth restriction, premature birth and fetal death. In Africa, the prevalence of eclampsia varies
from 1/100 to 1/1700 pregnancies, and Cameroon it happens in 0.92/1 100 deliveries. Our objective
was to determine among antidiabetic and gestational plants used in Cameroon thos.....
Mini Review
Hemifield Slide Phenomenon- the Double Trouble
Hridya Hareendran*, Padmavathy Maharajan and Fathima Allapitchai
DOI: 10.31031/MSOR.2022.03.000563
Hemifield slide is a sensory phenomenon seen as a sequela of heteronymous visual field defects. Although
a rare and under-recognised entity, hemifield slide phenomenon can adversely affect the quality of life.
Unfortunately, no specific guidelines have been proposed for the management. Fusional exercises, prisms
or surgical correction may be tried, but the diplopia is likely to worsen over time. stereo-typo scope
stereo-typoscope is a novel device which can overcome a hemifield slide for near and can help patients to read comfortably
Research Article
Inguinal Hernias Repair by Laparoscopy. (Pet).
DOI: 10.31031/COJNH.2022.08.000678
Introduction: The hernia affection is one of the processes that has been studied into much
detail and whose treatment pursues excellence, although many controversies are still yet to
be resolved. Laparoscopy repair of inguinal hernia is a treatment method that improves the
quality of management given to our patients.
Objective: To identify perioperative events, surgical complications and to evaluate the pain
referred for the patients who have had inguinal hernia repair by the laparoscopic method.
(TEP).
Method: A prospective and descriptive study was done on 80 patients who have had
endoscopic (TEP)repair of inguinal hernias between January 2013 and December 2020.
Result: We performed 100 hernioplastias by laparocoscopy in 80 patients. The male sex
predominated in a 5:1 ratio and.....
Opinion
Novel Approaches in Attaining Plant Diversity and Conservation: An Opinion Report
Mankind is facing challenges pertaining to food, energy, health, and environment, which
become more intense due the effect of climate change. Plants being the primary producers of
feed, food, fibre, shelter, energy, and the detriments of climate change are the basis of healthy
environments and ecosystems. Plant-based systems (fungi, microbes, and insects that live
on or in plants) play a vital role in addressing these challenges of food, energy, health and
environment. In order to address these challenges, there is a dire need to design projects
aiming at agricultural sustainability that is not only in line with ecosystem sustainability but
would ultimately lead to an improved GDP and economic condition of the country [1]. One of
the challenges that world faces due to population ga.....
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