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Mini Review
Stem Cell Culture System Simulating Continuous Fluctuating Pressure in vivo
Muhang Li, Junning Cui*, Ran Tang and Kai Li
DOI: 10.31031/ACSR.2021.02.000550
Abstract
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Full-Text
e-Pub
In order to improve the survival rate of stem cells in therapy after large-scale culture and transplantation
into patients, a stem cell culture system simulating continuous fluctuating pressure in vivo was proposed
in this paper. The system analogs the human pulse signals by regularly regulating the internal pressure. It
provides blood pressure training for the large-scale culture of stem cells in vitro, which can improve the
survival rate after stem cell transplantation, so as to elevate the success rate of cell therapy, and finally
provide direction for the development of new culture instrument
Editorial
Advanced Results in Biological Researches: Informational Structure and Info-Operability of the Living Systems
There are a few fundamental problems still unsolved up to date, in spite of the intensive
and multidisciplinary researches with modern/highly developed means of investigation
in biological structures, and of the great advances concerning especially the study of the
mechanisms involved in the micro-structuration from the simplest to the more complex
organism, that of the human. One of these major problems is to answer the question “what
is life” [1]. This concise question, as simple as it is comprehensive in terms of the broad
spectrum of scientific branches involved, lanced in the first half of the last century, remains a
great challenge even today. Another fundamental question remained since millennia on the
working table of scientists and philosophers refers to the understand.....
Mini Review
Combating Bacterial Infection of Rice Using Magnetic Nanoparticles
Panigrahi LL, Pradhan AK and Arakha M*
Magnetic nanoparticles like Iron Oxide Nanoparticles (IONPs) hold the fundamental class in
nanotechnology owing to their novel properties such as magnetism, biocompatibility, easy surface
modification and encapsulation, uptake efficiency and release. Their interdisciplinary nature can
be judged from the fact that it has also been applied in agriculture with the main purpose to increase
productivity and improve nutrient use. Novel Fe2
O3
nanoparticles are biocompatible and when efficiently
surface coated showed enhanced antimicrobial activity against gram positive as well as gram negative
bacteria. This review focuses on the potentials of IONPs as a competitive substitute of pesticides with
high antimicrobial activity against a wide range of plant pathogens along with low negative.....
Short Communication
Application of Machine Learning Methods in the blood glucose prediction
DOI: 10.31031/EPMR.2021.03.000566
Type 1 diabetes (T1D) is a chronic disease that requires patients to know the blood glucose values to
ensure their normal levels. The methods for predicting blood glucose are one of the areas of interest for clinical researchers. The literature describes many methods of predicting blood glucose, which require the determination of many activities, such as the time of insulin injection or emotional factors that may be susceptible to errors. To reduce the impact of individual activities, continuous glucose monitoring (CGM) is proposed to predict the level of glucose in the blood regardless of other factors. The paper presents the comparison of machine learning methods such as: linear regression, vector (SVR) and selected evolutionary algorithms (AE) to predict glucose concentration. The prop.....
Case Report
Craniotomy-An Art to Recast
DOI: 10.31031/PRM.2021.05.000601
Background: Destructive operations in obstetrics are performed to allow vaginal delivery and avoid
cesarean section in moribund fetus and mother. The incidence of destructive procedure ranges from
0.21-0.5%, craniotomy being the most common of all. The most common indication is obstructed labor
followed by hydrocephalus.
Cases: We here discuss series of cases where craniotomy was done without any side effects to the mother.
The cases were of arrest of descent of head and obstructed labour with intrauterine demise and one was
hydrocephalus baby.
Conclusion: It is important to revisit and master the technique of destructive procedures to save the
obstetric future of young mothers.
Mini Review
The Influence of Unidirectionally or Randomly Oriented CNTs on the Elastic Properties of Reinforced Composites
Kazakov IA* and Krasnovskii AN*
The paper studies the influence of CNTs on the elastic properties of unidirectionally aligned composites.
The nano-inclusions, whose properties could be characterized by three parameters (length, diameter,
Young’s elastic modulus), are assumed to be ellipsoidal and oriented along a macro-filler (for example,
glass fibers). The elastic properties of two systems: Matrix+CNT+Glass fibers and Matrix+Glass fibers
were determined and compared
Review Article
Psycho Neuroendocrino Immune (PNEI) Therapy of Cancer Beyond Melatonin
DOI: 10.31031/NACS.2021.06.000641
The recent advances in psycho-neuroendocrino-immunology (PNEI) have demonstrated the existence
of a natural anticancer neuroendocrine system, mainly expressed by the pineal gland, endocannabinoid
system, oxytocin, and Ang 1-7. Moreover, cancer progression has appeared to be associated with
a progressive decline in the pineal and cannabinoid system functions. A new approach to cancer
therapy according to a PNEI strategy could simply consist of the correction of the main cancer-related
neuroimmune and neuroendocrine alterations through the exogenous administration of the same human
natural anticancer molecules, whose production declines with cancer progression. PNEI therapy of
cancer, because of its complete lack of toxicity, could be applied also to patients, who failed to respond
t.....
Mini Review
Fetal Exposure to Hyperthermia and Future Dairy Cattle Production Challenges
DOI: 10.31031/NRS.2021.10.000727
The objective of this article was to emphasize effects of fetal exposure to hyperthermia and its
consequences on future dairy cow performance. Fetal growth especially during late gestation depends
on nutrients provided by dam via placenta. Thus, any factor that disrupts this relationship would be
reflected in growing fetus biology and may have long-term negative effects on dairy cow performance
and longevity. Decreased dry matter intake and milk yield as well as suppressed immunity have been
shown in heat-stressed lactating dairy cattle. However, it seems that heat stress impacts on pregnant
cow may be more drastic. Under high ambient temperatures, blood flows toward peripheral tissues
instead of uterine and placenta to sustain thermoregulatory processes. Altered blood flow would re.....
Review Article
New Research Search for Life Satisfaction in Family Environment and Presence of Children in the Family
DOI: 10.31031/NRS.2021.10.000728
In the process of studying human satisfaction in general and life satisfaction in particular, the most widely
used is the Life Satisfaction Scale (SWLS), Subjective Well-Being (SWB), FACES II - The Family Adaptability
and Cohesion Evaluation Scale with a cognitive component (life satisfaction) and an affective component
(positive and negative emotions or emotional balance). These commonly used scales provide strong
evidence of acceptability, reliability, validity and invariance for gender, while there is mixed evidence
of invariance by culture and age, as well as the roles of marital status and educational level. This review
article proposes an experimental operationalization between marital status and the presence of children
in the family. The aim is to deduce the relationships be.....
Review Article
Application of Electro Analytical in Trace Metals Determinations: Environmental and Industrial Samples
Abdel Hameed RS*, Al Bagawi AH, Aljuhani Enas H and Farghaly OA
Determination of the trace elements in both environmental and industrial sample are of great importance
and attractive field for many researchers and scientists, and of high economic and environmental impact.
Electro analytical methods show a remarkable sensitivity, broad scope and very low quantitation limit.
A review of the modern electro analytical techniques, namely, cyclic, linear sweep, square wave and
stripping voltametric techniques, in the trace metals determinations is highlighted. This review focus on
the environmental and industrial applications used for each mode of electro analytical techniques.
Keywords: Electro analytical; Cyclic voltammetry; Stripping techniques; Environmental applications,
Industrial applications
Opinion
Things to Consider When Implementing Building Blocks Approach for Global Sustainability Reporting Standards
Jongsoo Han* and So Hyeon Kang
The Trustees of the IFRS Foundation has released three documents since September 2020
delving into the convergence in global sustainability reporting standards. SASB, GRI, TCFD,
CDSB and CDP have agreed upon the collaboration to form the ‘building blocks’ approach
for global non-financial reporting [1-3]. IFAC and IOSCO have also announced their support
for this approach. As for the scope, the trustees announced a ‘climate-first’ approach that
prioritizes Environmental issues among non-financial factors which compose of corporate
sustainability. Inter alia, climate change and Greenhouse Gas (GHG) emissions will be the first
focus. After that, it takes into consideration of wider environmental factors associated with
financial risks. Then, the trustees plan to broaden its wo.....
Case Report
Decreasing the Risk of Incisor Root Resorption during the Orthodontic Management of Palatally Impacted Canines: Case Report
Palatally impacted canines can lead to root resorption of adjacent incisors; root resorption can also
result due to orthodontic treatment when unplanned orthodontic movements occur close to the incisors
roots. Care should be taken during the first stages of tooth movements in order to avoid root resorption.
The first tooth movement of the impacted canine should aim to take the canines away from the roots of
incisors. This case report represents an example how we avoided root resorption of teeth adjacent to the impacted canine by taking the canines away by a modified transpalatal bar
Short Communication
HaP/SBA-3 Nanostructured Composite to Remove Fluoride Effectively from Contaminated Water
Jorgelina Cussa, Claudia G Lopez and Oscar A Anunziata*
DOI: 10.31031/RDMS.2021.16.000883
Highly ordered pore mesoporous silica composites, like SBA-3 and hydroxyapatite (HaP) nanocrystals,
characterized by X-ray diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), Scanning
Electron Microscopy (SEM), Transmission Electron Microscopy (TEM) and textural properties, were
successfully applied to remove fluoride from contaminated water. The proposed procedure to prepare
HaP/SBA-3 was successful, which acts as supports to anchor the HaP crystals, in nanometer-scale (<2nm),
with higher fluoride retention from contaminated water. The free OH- groups of HaP nanocrystals, within
the host, facilitated the high-performance fluoride trapping. The fluoride retention activity was much
higher than that of pure HaP and the composites HaP/SBA-15 and HaP/MCM-4
Mini Review
The Pathogenesis and Influencing Factors of Diabetes
Sun Qian, Feng Jin and Li Chun-Yang*
DOI: 10.31031/IOD.2021.05.000621
Diabetes is an endocrine and metabolic disease and has become a pandemic disease
that threatens the health of almost all human beings. Diabetes is a metabolic syndrome with
glycolipid, protein and amino acid metabolism disorder and the increase of blood sugar caused
by absolute or relative deficiency of insulin. Hyperglycemia is the main feature of diabetes and
the main cause of various complications [1]. In recent years, the number of patients with
diabetes has increased year by year. In the 21st century, diabetes will be one of the most
serious public health problems throughout the world, which not only imposes a great burden
on society and individuals, but also is accompanied by higher residual rate and mortality [2].
In a word, diabetes has seriously threatened people’s life
Opinion
Cancer Patients’ Lives Matter
Ming C Liau* and Linda Liau Baker
DOI: 10.31031/ACAM.2021.06.000649
Cancer mortalities are on the very top in most industrialized nations for a very long
time. A notable exception is the USA. The cancer mortality of USA is second to cardiovascular
diseases. The cancer mortality of China was the second to infectious diseases 50 years ago
but is now surged to the first place. These mean that the health profession did not make a
good progress to save the lives of cancer patients in the past. Cancer therapy is dominated
by cytotoxic agents in the past. It is long overdue to deliberate cancer therapy employing
toxic agents. Cytotoxic chemotherapy was a tragic byproduct of the World War II. Toxic sulfur
mustard gas bomb was a weapon during the war. Victims of sulfur mustard gas all showed
deficiency of lymphocytes. That finding inspired oncologists to em.....
Mini Review
Prevention of Drug Osteonekrosis of Jaws: Current State of the Problem
Elena M Spevak* and Dmitry Y Christoforando
DOI: 10.31031/MRD.2021.07.000651
The problem of prevention of medicinal osteonecrosis of the jaws is one of the lively discussions
of the last decade in dentistry. Osteomodifying drugs (bisphosphonates, denosumab) most often cause
medicinal osteonecrosis of the jaws. They are used to suppress resorption in osteoporosis, metastatic
lesions of the bones of the skeleton, aseptic necrosis of the femoral and humerus heads, various genetic
diseases accompanied by osteogenesis imperfecta and osteopenic syndrome. Due to the high prevalence
of osteoporosis and malignant neoplasms in the population, the prescription of osteomodifying drugs
has become a routine practice. Medicinal osteonecrosis of the jaws is an iatrogenic disease that is difficult
to treat and leads to serious consequences in the form of a pathological fract.....
Opinion
What’s Next for mRNA Vaccines?
DOI: 10.31031/NRS.2021.10.000726
The recent COVID-19 pandemic has shone a spotlight on a revolutionary technology
called messenger RNA (mRNA). What is not so well known is that mRNA has been in the
research and development sphere for about three decades. Now that the Pfizer/BioNTech
and Moderna vaccines have been shown to be both safe and effective, researchers expect to
be able to use this technology to create rapid-response vaccines in the future. Not alone do
the mRNA vaccines have the potential to swiftly combat viral pandemics, but also generate
promising treatments in other strategic areas, such as immunology, oncology, and rare
diseases. Personalized Medicine
Mini Review
Rhinogenic Orbital Complications
DOI: 10.31031/NRS.2021.09.000725
The clinical symptoms and the choice of treatment tactics of rhinogenic orbital
complications depend on the nature and location of the inflammatory process. In this regard,
various clinical classifications have been proposed in the literature, and they usually cover
purulent forms of complications and do not always allow the selection of the right treatment
tactics. The purpose. To clarify the forms of rhinogenic orbital complications, which can allow
choosing treatment tactics based on clinical symptoms and modern diagnostic methods.
Materials and methods. 130 patients with rhinogenic orbital complications were examined
and treated. 61 of them were under 15 years old. Patients were examined by general clinical,
otorhinolaryngological examinations, endoscopy of the nasal cavity, CT.....
Mini Review
The Safety of Combination of Food Additives in Food Products
Natalija Atanasova-Pancevska* and Aleksandra Markovska
DOI: 10.31031/NRS.2021.09.000724
Additives are a group of organic and inorganic compounds that are not raw materials and are used in the production of food in order for the products to be of better quality or longer lasting, to protect the taste,
or to improve the taste or appearance. Some of the additives have been used for centuries, for example
by salting meat or using CO2
in wine. The main groups of food additives are antioxidants, colors, flavor
enhancers, sweeteners, emulsifiers and stabilizers and preservatives. The FAO has also given a definition
of additives, according to which additives are substances that are intentionally added to products,
usually in small quantities, have no nutritional value, and the purpose of their addition is to improve
the appearance, smell, taste, consistency or durability of t.....
Mini Review
Pre-cooling of Human Top Athletes and Sport Horses Under Heat Stress: An Opportunity or Wishful Thinking? A Review
DOI: 10.31031/APDV.2021.08.000695
In this review paper attention is given to cooling methods applied in human top athletes and in sport
horses under conditions of heat stress. Three cooling principles are addressed: pre-competition cooling,
per-competition cooling and post-competition cooling. Each of these are elaborated with respect to
practicality and to their advantages and disadvantages. Post-cooling is generally accepted in both species
but should be executed in the best possible way. Pre-cooling has been subject of study in human top
athletes. Effects have been determined but not each method is applicable or effective and even not in each
discipline. The preferred method is cool-cold water immersion of endurance athletes. In sport horses,
post-competition cooling is common use. However, several methods often .....
Short Communication
Pears Fortified with Minerals
DOI: 10.31031/NTNF.2021.06.000634
The main objective was to obtain a ‘snack’ that has a high content of minerals (principally calcium and zinc)
through an osmotic dehydration/impregnation process and an extended shelf life that can be achieved by
posterior applying a combined drying (convection drying and microwave). The pear slices were immersed
in an aqueous solution, which contained lactate calcium 5%m/m, and acetate zinc (0,1%m/m) (49 °Brix).
The calcium and zinc concentrations were measured by a flame atomic absorption spectrophotometer
and ICP-OES, respectively. The impregnation with minerals was analyzed during time. The samples were
osmotic dehydrated/impregnated for 1h. Then, they were dried using a combined method (microwave
and hot air convection simultaneous) during another 10-12min to reach 20% of .....
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