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Short Communication
Investigation of Pharmacological Activity of the Pharmaceutical Forms from Summer Savory (Satureja Hortensis) Leaves Essential Oil
DOI: 10.31031/NRS.2020.4.000588
Abstract
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Background and Objectives: Satureia hortensis (summer savory) from Lamiaceae (labiatae) family is valuable by its rich existence of essential oil. Taking in account several pharmacol ogical effect of mentioned genus essential oil’s compounds, it was investigated the Armenian flora Satureja hortensis essential oil chemical composition, obtained pharmaceutical forms and studied antimicrobial, anti-inflammatory antinociceptive and wound healing activities.
Material and Methods:
Satureia hortensis essential oil chemical composition analysis was carried out by gas chromatography-mass spectroscopy (GC-MS) method. Antimicrobial effects of the essential oil were studied by disc-diffusion assay. The evaluation indicator for antimicrobial .....
Review Article
Oils and Fats-Largely Unexplored Source of Nutraceuticals
Olivia Dhara and Pradosh P Chakrabarti*
DOI: 10.31031/NTNF.2020.05.000603
Nutraceutical is a term derived from two words, “nutrition” and “pharmaceutical”. This particular group of food derived products shows various health benefits. These products are being used in the treatment of cancer, arthritis, osteoporosis, cardiovascular diseases, retinopathy, age-related problems and many more physiological and neurological disorders. In the post-COVID-19 scenario the whole world is looking for natural product-based treatment methods and immunity boosting products to improve the general wellness of people. Oils and fats are known as the category of food that supply more than double the energy compared to proteins and carbohydrates. It also gives texture and palatability of foods and enhances the taste of foods by providing characteristic.....
Mini Review
The Means by Which COVID-19 Could Cause Extinction of All Life on Earth
DOI: 10.31031/EAES.2020.07.000656
Loss of habitat for human animals on Earth is rapidly approaching. Shortly after habitat for humans is gone, our species will go extinct. The likely route by which near-term human extinction will occur is presented here, taking into account abrupt, irreversible climate change, the ongoing Mass Extinction Event, and the consequences of COVID-19.
Short Communication
The Biggest Health Problem SARS-COV-2 and It’s Solution
DOI: 10.31031/ETUN.2020.03.000557
Today COVID-19 pandemic is deadly big that we cannot imagine who and world scientists fail to search proper medicine or substitute since the 6th month and till now about 4,36 lakh known death taken place in the world according to Danik Bhasker Daily newspaper India. The reason behind it that we are bound by the law system that we cannot give any medicine or substance without the approval of WHO and other comporting authorities. World’s scientist is working in older pattern to search substitute, but they did not want to take new medicine because it needs to go very long process and go through proper channels it is a very lengthy process and time-consuming. Now no law and technic ready to save lives. My article of Treatment of COVID-19 by bile juice p.....
Mini Review
Bioestimulantes in the Agriculture
DOI: 10.31031/MCDA.2020.07.000652
The great challenge of modern agriculture is in the sustainable production of food without compromising natural resources. Various technologies to increase productivity have been used in agriculture, biostim-ulants are increasingly available in a variety of formulations and with varied ingredients on the market, therefore, there is a need for studies on agronomic benefits to ensure the viability of use in the most diverse cultures.
Mini Review
Selected Applications of Generative Adversarial Networks: Mini Review
Gokce Iymen, Gizem Tanriver, and Onur Ergen*
Generative adversarial networks have become increasingly popular since they were first introduced in 2014. Many variants of GANs have been developed over the years and employed in a range of applications from computer vision to audio generation and medical imaging. As its applications in computer vision have been widely explored by the artificial intelligence community, here, we focus on more specific applications of GANs, namely audio generation and medical image synthesis. In the age of big data, these two fields still struggle with the scarcity of labelled data, hence they benefit greatly from the capabilities of GANs.
Short Communication
Colchicine Plus Fosfomycin in Coronavirus Infection
DOI: 10.31031/NRS.2020.4.000587
Following Covid-19 outbreak, the scientific community focused on several alternatives for either preventing or therapeutically treating the illness. It is clear enough at this time that vaccines will not be available at least for the few months to come. An association between an antibiotic (Azithromycin) and an antimalarial drug (chloroquine) has already been tested
Case Report
Surgical Management of Nondysraphic Giant Thoracic Intramedullary Lipoma: A Case Report
DOI: 10.31031/TNN.2020.03.000565
Background: Spinal cord intramedullary lipomas are rare and commonly associated with spinal dysraphism and account for 2% of intramedullary tumors, while lipomas not associated with spinal dysraphism are even less frequent, accounting for 1% of cases. Most of the intradural lipomas are subpial and not intramedullary.Objective: We aim to provide a summary of the pathology, clinical presentation, and management strategies of true giant thoracic intramedullary lipoma without dysraphism with review of the literature.Case presentation: We report a case of a patient with giant thoracic intramedullary lipoma who presented with paraparesis and bladder dysfunction. There were not imaging studies that evidenced dysraphism. The patient underwent surgery an.....
Opinion
Fuckbots: The Challenges of Sexual Robotics
The first approach to the field of fuckbots, or sexual robotics (also lovotics, dildonics), shows us an astonishing result; we do not have data about them. Taking into consideration that sexual industries (porn, gadgets) provide incredible benefits, the lack of open interest into such research area is, at minimum, a complete absurdity. The estimated revenues for the next generation of SexTech (and sexual robotics, as n included category) systems is estimated on US$122 billion by 2026. The demand and revenues are exponential but. We do not see departments of sexual robots at universities, nor students doing their final Grade projects on such topic, not academic events are hold on sexual technologies or big companies investing into this field. A few unknown and not relevant professionals hav.....
Opinion
Sodium/Glucose Cotransport and Treatment of Diabetes
DOI: 10.31031/IOD.2020.04.000590
There are two ways for glucose uptake depending on metabolic needs and glucose availability. These ways included passive (facilitated diffusion) and secondary active transport. Passive transport is movement of substances from high to low concentration. On the other hand active transport is movement of substances against its concentration gradient, unlike passive transport, the cell expends energy. In passive process, as a result of impermeability of plasma membrane for polar substance as glucose, the cellular uptake of glucose is accomplished by special carrier proteins called glucose transporters. The most significant carrier proteins are GLUT1-4. GLUT1 and GLUT3 are located in the plasma membrane, and they a.....
Mini Review
Adomet Synergistically Enhances the Chemotherapeutic Action of Cisplatin and Improves Drug Efficacy in Jhu-Scc-011 Laryngeal Squamous Cell Carcinoma
DOI: 10.31031/NACS.2020.05.000603
Laryngeal squamous cell carcinoma (LSCC), is characterized by an aggressive clinical behavior and lack of specific targeted therapies. Thus, novel therapeutic approaches that take advantage of the combination of anticancer natural compounds and chemotherapeutic molecules currently used for LSCC are strongly necessary. S-adenosyl-L-methionine (AdoMet), the main biological methyl donor, is well known for its antiproliferative, proapoptotic and antimetastatic effect in several type of human cancer. In the current study we investigated the antitumor activity of AdoMet in combination with cisplatin (cDDP), an agent usually used in cancer therapy of LSCC, in JHU-SCC-011 cells and we explored the underlying mechanisms. We found that the combination of 200μM AdoMet/0.18μM cDDP syner.....
Research Article
The Effect of Rhizophora racemosa (Red Mangrove) Leaves and Root-Bark on Testosterone and Oestrogen Levels in Blood Serum of Broilers
Shidi SA*, Wekhe SN, Amakiri AO and Owen OJ
An experiment was conducted in the Teaching and Research Farm of the RSUST. Port Harcourt to evaluate the effect of Rhizophora racemosa (Red Mangrove) on testosterone and oestrogen levels in blood serum. Using a 2x3 factoral arrangement in a completely randomized design experiment. The birds were randomly allocated into seven treatment groups. A, B1, B2, B3, C1, C2, and C3 of 15 birds per group. All groups were replicated thrice with five birds. Pulverized R. racemosa leaf and root-bark was administered to the birds faded levels of 70, 80 and 90 grams for both leaf and root-bark. The highest levels of inclusions (90gm) were used. The experiment lasted eleven weeks. Results obtained showed that R. racemosa significantly (P<0.05) increases testosterone and Oestrogen level in broilers.
Research Article
The Implementation of Animal Assisted Therapy Programs in Substance use Disorders
Abel Baquero E*, Martin JR and Montolio MM
DOI: 10.31031/PPRS.2020.04.000577
Animal Assisted Therapy (AAT) is presented as a complementary program that, together with rehabilitation treatment, favors the clinical evolution of the patients who participate in it. The integration of AAT in the healthcare and health field has been increased in recent years; highlighting the growing interest in AAT programs, along with numerous studies that examine the benefits and efficacy of different therapeutic approaches with animals [1,2], after different and novel pilot experiences in substance use disorders [3], it seems that TAA is an intervention approach with utility in the rehabilitation processes of people with disorder substance use.
Short Communication
Ornamental Plants Help to Beautify your Surrounding and Liberate Oxygen
Manju Das, Biswas SK, Zaman S, and Mitra A
DOI: 10.31031/MCDA.2020.07.000651
Utility of keeping ornamental plants not only beautify your place of residence but helps to add oxygen to purify air. Plants absorb more carbon-di-oxide during daytime and prepare their own food. Oxygen releases to the surroundings and helps to breathe properly. Dates back from Mesopotamian era human settlement has a tendency to beautify their surroundings with ornamental plants. (“First use of orna-mental plants in the history of urbanization” by Osman Zeybek [1]). Different chrome in leaves are quite attractive. It attracts human eyes too. Keeping ornamental plants and decorate is a natural tendency of human habitation.
Mini Review
Fixed, Random and Mixed Statistical Models for Field Experimentation
Robson da Silva Ramos*, Fabian Santana Silva and Álvaro Eugênio Duarte de França
DOI: 10.31031/MCDA.2020.06.000650
One of the stages of the experimental planning phase is the determination of statistical models. To do this, it is important to understand the nature of the sources of variation. The determination of fixed and ran-dom factors auxiliary directly in the previous choice of statistical models, as well as in the experimental design. The prior choice of statistical models in field experiments is important for otimizate representa-tiveness and accuracy of the data.
Case Report
Chronological Experience of Alice in Wonderland-Like Visual Impairment Due To Correlating Physical Abuse till Teenager Age
Bittmann S*, Alieva EM, Villalon G and Luchter E
DOI: 10.31031/RPN.2020.04.000594
Alice in Wonderland Syndrome (AIWS) was named after Lewis Carroll’s description in his novel. It was in 1955 that John Todd, a psychiatrist, first described this entity. Todd described it as “Alice’s Adventures in Wonderland” by Lewis Carroll. The author Carroll suffered from severe migraine attacks. Alice in Wonderland Syndrome is a confusing state of seizures that affect visual perception. AIWS is a neurological form of seizures that affect the brain, causing impaired perception. The patients describe visual, auditory and tactile hallucinations and perceptual disorders. The causes of AIWS are not yet known exactly. Cases of migraines, brain tumors, depression episodes, epilepsy, delirium, psychotropic drugs, ischemic stroke, EBV, mycoplasma and malaria infections correl.....
Research Article
Correlation between Limited Prosocial Emotions and Empathy in Adolescents Clinical Population
Serment M, R de la Peña F* and Delgado AR
DOI: 10.31031/RPN.2020.04.000595
The present study aims to determine the correlation between Limited Prosocial Emotions (LPE) specifier for disruptive behavior disorders and the cognitive and affective subtypes of Empathy in a clinical population of adolescents in Mexico City. Sample was integrated with 49 participants between 13 and 18 years old from the Clínica de Adolescentes, an outpatient service of the Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz. All adolescents included, received LPE specifier diagnosed by certified psychiatrist using a categorical and dimensional instrument. The Global Empathy Scale parent/tutor and self-report versions were used to evaluate cognitive and affective empathy subtypes. The results showed an inversely correlation (r=-0.54, p<0.05) between the severity.....
Research Article
Acute Abdomen as a Presentation of Covid 19 in Children: Our Early Experience
Samiul Hasan*, Ayub Ali and Umama Huq
DOI: 10.31031/RPN.2020.04.000596
Background: COVID-19 is currently a public health emergency around the world. Increasingly more people are being identified with this deadly viral disease. Though children experience a milder disease course, severe and life threatening disease has also been reported. An atypical presentation may delay the diagnosis, isolation, and treatment. The aim of this study was to share our experience of atypical presentation of COVID-19 cases as acute abdomen in children.Method: We retrospectively reviewed data of all children diagnosed to have COVID 19 in our department between April to June 2020. Epidemiological & clinical data of children presented with acute abdomen were retrieved and placed in Microsoft Excel 2016. The data were then analyzed and literature reviewed.Result: Tota.....
Case Report
Ectopic Hydatidiform Mole a Case Report
Nora Awad Elkarim Bashir Mohamed*, Laila Moharram and Hedaya Atalla M Alblewi
DOI: 10.31031/NRS.2020.4.000586
Background: The incidence of ectopic Hydatidiform mole is presumed to be 1.5 in a million, Making suspicion of the diagnosis less likely. It is important to differentiate between a conventional ectopic and a molar ectopic gestation as they both have the same clinical presentation; however histopathologic fea-tures are different. Reaching the proper diagnosis helps in appropriate follow up and counseling.Case Report: A 32 years old, Gravida 5 para 4, presented to the emergency department with 5 weeks plus 6 days amenorrhea and lower abdominal pain. In view of a high Quantitative beta human chorionic gonadotropin (30870 mIU/L), an empty uterus and a complex mass in the left tube 9x8 mm, the patient had laparotomy with left salpingectomy, histopathology of the specimen reported complete mole.....
Review Article
Recent Insights into β-Carboline Alkaloids with Anticancer Potential
Lakshmi Manasa K, Swetha Yadav S, Srikanth D, Narayana Nagesh* and Malli-ka Alvalaa
DOI: 10.31031/MADD.2020.03.000554
Development of nature inspired new drug molecules through medicinal chemistry approach has a profound success on drug discovery. Efforts of chemists have succeeded in developing semi- synthetic derivatives to dominate the authentic natural product in terms of drug-likeness properties include increased potency, reduced toxicity, and patient compliance. β-carbolines a family of indole-based alkaloids, remained as a privileged scaffold to exhibit anticancer effects through numerous mechanisms. This review inclines the readers towards the ongoing developments (2017-2019) on cytotoxic effects of β-Carboline with a significance on structure based rational drug design, multiparameter lead optimization strategies, relevant SAR studies of this particular fr.....
Research Article
What Would it Mean if White Sharks, Carcharodon Carcharias, Possessed Disconjugate Optokinetic Stimulation?
Erich K Ritter* and Andreas Dellios
DOI: 10.31031/EIMBO.2020.03.000570
Disconjugate eye movements are a feature of some animal species, but it is unknown whether white sharks, Carcharodon carcharias, possess independent eye moments, as well. Here, the question of what it could mean if they exhibited this ability is discussed. Video evidence shows the possibility of independent eye movements with a white shark looking at two distinct targets aimed at them consecutively. Different interpretations of the videos core frames are discussed with disconjugate optokinetic stimulation as the most highly advanced possible explanation of this observation. Such an ability would enable a white shark to scan its entire visual field and confer an advantage in terms of being able to observe two prospective food sources on either side of its head, allow.....
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