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We at Crimson Publishing are a group of people with a combined passion for science and research, who wants...
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Crimson is an Open-access academic publisher has a vision to establish Open Science platform that seeks to provide equal opportunity for all, share and create knowledge, and enables the scholarly world to engage in a dialogue with the science in a more effective manner. Our efficient and transparent ways of peer-review procedures provide impact metrics for articles and researchers.
Our mission is to offer quality editorial services, significant resources into technology innovation, freely accessible, discoverable scientific information, and high-quality publications. Our impact metrics provide real time view on details such as views, downloads, and citations; demographies; aggregated author impacts; how author’s profile is perceived; social buzz; career visibility; integration across platform; and functionality.
Opinion
Application of Quality by Design (QbD) Approach in Regenerative Medicine
Mamta Thakur* and Abhilash Thakur
Abstract
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Regenerative medicine are the chemical/biochemical systems that mimics normal functions of human systems. The objective of regenerative medicine is to replace or regenerate human cell, tissue or organs. In this article emphasis has been given to the computer aided design of the biochemical systems to restore & enhance therapeutic value of the medicine, to reduce the journey time of the medicine from laboratory to market, to develop cost effective methodologies and to eliminate trail-error dynamics from the area of medicine. Over and above in some cases computer aided drug design also succeeded in eliminating some animal trials.
Research Article
Rainwater Harvesting for Fighting Climate-Induced Water Poverty Problem in Coastal Bangladesh
Bangladesh is widely known as one of the most vulnerable countries to climate change effects with coastal areas prone to intense climatic extreme events. The climate-induced extreme events such as sea level rise, floods, cyclones, storm surges, and salinity intrusion greatly affect water supply system in that region. Rainwater Harvesting (RH) from the rooftops can be a good alternative source of safe water as the country receives ample (on an average 2400mm) rainfall per year that could reduce water crisis problem in the coastal region. Water demand and supply equation can be a measurement tool to measure rainwater availability to meet water demand over the whole year. But utilizing rainwater needs government support regarding the RH policy for sustainable use of ra.....
Mini Review
Is it all in the Wrist? The Potential of Activity Trackers to Rise Physical Activity in Cancer Survivors
A growing body of evidence suggests that higher levels of physical activity are inversely associated with treatment side-effects and mortality in cancer survivors. Conversely, a limited percentage of cancer patients achieve physical activity goals and fitness compared with age-matched peers or other chronic medical conditions. In the last years, the next generation of activity trackers has integrated several parameters of physical fitness and mobility measurements. These multi-task devices go beyond objective physical activity measurements. Due to its functioning based on integrated platforms, clinicians may experience a unique opportunity to incorporate more active behaviors into their patients’ lives. This mini-review will discuss .....
Research Article
A Review and Meta-Analysis of The Association Between Vitamin D and Carotid Atherosclerosis in Patients with Type-2 Diabetes
Xin Mou*, Di Yi Zhou and Dan Yang Zhou
Background and aims: Many scholars have explored the relationship between carotid atherosclerosis） and vitamin D in patients with type 2 diabetes. Summarize these studies and draw the conclusions.Methodology/Principal Findings: An electronic search was conducted of several databases, including PubMed, Web of Science, EmBase, Cochrane library, China National Knowledge Infrastructure(CNKI), WANFANG DATA, for papers that describe the association between serum 25-hydroxyvitamin D(25OH-D) related to CAS in patients with type 2 diabetes(T2D).Of these, 6 met our inclusion criteria from which the number of patients.Result: This meta-analysis indicates that serum 25OH-D concentration is negatively related to CAS in patients with T2D(P=0.000). There is heterogeneity among t.....
Research Article
Methodology for Licensing Burnup Credit in Nuclear Criticality Safety Analysis: A Calculational Basis
Leotlela MJ* and Manyaapelo OB
There are many nuclear power stations (NPSs) that are currently operating but are rapidly approaching the point where they will be running out of storage space in the spent fuel pool (SFP). In order to prolong their operation and prevent them from being shut down by the nuclear regulator, many have opted to follow the neutron absorber inserts route while others have opted for spent fuel casks. The other option for recovering the storage space lost as a result of fresh fuel calculation methodology is to take credit for burnup. This technique presents another option for saving storage space in the SFP or ISFSF. While few countries have licensed the technique, the few countries that have taken the lead in this are the USA, Japan and France [1-5]. The reasons for not doing so .....
Editorial
The Case for Researching Biomechanics and Human Movement Using a Stochastic Model in a Peer Reviewed Journal to Generate Qualitative Evidence
The Evidence Based Practice (EBP) of biomechanics and human movement (hereafter
BHM) has been handcuffed by a lack of peer reviewed, high level, valid and clinically applicable
evidence that has dampened the ability to use Sackett’s model of Evidence Based Medicine
(EBM) clinically [1-3]. Current journal research protocols for EBM follow a deterministic
model. In this model there are one or two dependent variables to be investigated and
simultaneously all independent variables that could dampen the results are eliminated or
controlled with an algorithm or statistical formulae. The deterministic model has both a high
intratester (the same tester repeatedly gets the same results) and intertester (different testers
repeatedly get the same results) efficiency a for it to be deemed hi.....
Research Article
Study on Plant Growth Promoting Activities of Azotobacter Isolates for Sustainable Agriculture in Myanmar
Plant growth promoting Rhizobacteria (PGPR) enhance the plant growth and productivity through wide variety of mechanism. In this paper, a total of 6 isolates belonging to Azotobacter spp. were isolated from different rhizosphere soils collected from Kyaukse Township, Mandalay Region. The isolated bacterial cultures were characterized morphologically, culturally and biochemically and then they were identified as Azotobacter. They were screened for their plant growth promoting traits. Results revealed that isolated strains are capable of fixing nitrogen, solubilizing phosphorus and synthesizing indole compounds. It was concluded that among the isolates, “U” is the best isolate for all these activities. The results of the pres-ent experiments can be utilized in biofertilizer p.....
Research Article
The New Oral Anticoagulants (NOACs) Between Prevention of Systemic Thromboembolism and Bleeding Procedures in the Dental Office: Review of Literature and Case Report
There is insufficient data on the use of NOACs during bleeding procedures in the dental office versus old oral anticoagulants. The current therapeutic indications are mostly based on the pharmacodynamics or on small cohort studies. Data from the literature has been reviewed in this respect. A 62-year-old patient under treatment with Rivaroxaban complained of transitory pain in the posterior upper-right jaw. The extraction of second upper right molar was performed, followed by the suture of the socket. According to the therapeutic indications and the available literature on the subject, the administration of the anticoagulant was not ceased. In the following days, repeated bleeding episodes were reported in direct correlation with the timing of Rivaroxaban administration and d.....
Review Article
Metabolic Disequilibrium and Aging: Modifying Favorably with Calorie Restriction and Calorie Restriction Mimetics
Metabolic disease and aging: There are increasing evidence that metabolic disequilibrium and disorders
influence the aging process and survival including the quality of life (QOL). The adipose tissue mediates
various age-associated metabolic disorders such as insulin resistance (IR), metabolic syndrome (MetS),
dyslipidemia and type 2 diabetes mellitus (T2DM), altogether which can negatively affect the lifespan and sends signals to modify the aging process in various tissues and organs. The role of master-switch and genomic guardian, p53 is important in this context. Calorie restriction (Cr): The energy needs are determined by the body composition, especially the fat free lean mass and level of physical activity, and there is a change in nutritional needs during the middle age and later......
Case Report
Religiosity and Yoga in Parkinson’s Disease Patients
Docu Axelerad Any, Alina Stroe and Docu Axelerad Daniel
Objectives: This study was led to analyze the clinical correlates considering the effectiveness of yoga exercises and religiosity on Parkinson’s disease (PD) patients.Methods: Measures of mood, neuropsychological function and motor activity were assessed in 14 cases with Parkinson’s disease and 12 persons with vestibular syndrome. PD patients received L-Dopa and dopaminergic agonists treatment.Results: The improvements in the functional activities during the study period were not clinically significant. Subjectively, the participants acquired delectation and relaxation from the yoga sessions. Keywords: Parkinson’s disease; Religiosity; Yoga; Vestibular syndromeAbbreviations: PD: Parkinson’s Disease; MMSE: Mini-Mental State Examination
Opinion
Aligning Belt and Road with Africa’s Development
Anywhere Chinese leaders visit, the Belt and Road goes with them-in speeches, if nothing else, but also frequently in economic pacts and even formal diplomatic documents. That was the situation during this year FOCAC Summit meeting in September. The Belt and Road strategy is centered on infrastructure development, especially regional transportation and connectivity projects.
Editorial
Harnessing Africa’s Demographic Dividend
The 28th African Union Summit declared “Harnessing the Demographic Dividend through investments in youth” as its theme, which connects the “Agenda 2063” that offers a comprehensive development vision for Africa. Regardless, African youth faces numerous challenges and opportunities in the fields of skills training, technology, entrepreneurship, agribusiness, advocacy, and political involvement.
Opinion
FOCAC: An Effective Platform for Collaboration
The Forum on China-Africa Cooperation has a lot to do with economic growth across countries in the African continent. Africa and China agreed to build FOCAC into a brand for China-Africa collaboration and a flagship example of international co-operation with Africa under the principle of achieving shared prosperity for mankind through discussions and collaboration.
Opinion
Promises and Challenges: Recent Development of Granular FePt-L10 Thin Film Material for Heat Assisted Magnetic Recording
At room temperature, perpendicularly ordered L10
FePt thin film exhibits extremely high
uniaxial anisotropy with easy axis oriented along the ordering direction [1]. The relatively
low curie temperature and high temperature gradient of the anisotropy field near the Curie
point of the L10
FePt makes it almost perfect as a recording media for heat assisted magnetic
recording (HAMR) technology [2-5].
Opinion
Urgent Need for a Performance-Based Approach for Seismic Assessment and Design of Fastenings Used in Structural Applications
Fasteners or anchors are widely used to form the connections between non-structural or structural components and the primary reinforced concrete structure. The design of fastenings in concrete is traditionally performed using force-based method, where the design load for the fastening is calculated corresponding to different possible failure modes and the lowest value defines the allowable load that can be applied for the anchorages [1-4]. Under seismic actions, the fasteners in concrete are subjected to relatively strong demands of cycling tension and shear loads as well as opening and closing of cracks intercepting the fasteners (Figure 1).
Research Article
PV Syst Based Modeling and Validation of Photovoltaic Cells
Bouzguenda M, Selmi T* and Natarajan R
Photovoltaic (PV) cells are modeled using numerical models that illustrate the performance of the voltage and the current generated by the PV cell. Those two physical quantities depend on some manufacturing and environmental parameters such as the temperature and the incident irradiance. Accordingly, this paper shows the impact of such parameters on the electric behavior PV cells. An electronic circuit; made up of a photocurrent source, a junction diode of two semiconductor materials, N-type and P-type, a series and shunt resistances; represents the PV cell considered within this paper. Within this paper, real data of the AEGAS-P605-250 PV module has been used through PV syst. 6.6.3 Software Tool to highlight to impact of manufacturing and climate parameters on the cell’s el.....
Mini Review
Botanic, Phytochemistry and Pharmacological Aspects of Phyllanthus Amarus Schum & Thorn as Powerful Tools to Improve its Biotechnological Studies
Phyllanthus (Euphorbiaceae) is a native genus of the American continent representative medicinal plant with very high number of species (more than 1,000) located in tropical and subtropical countries. In Brazil, this genus is represented by over than 100 specimens, that are widely distributed in different environments. In fact, Phyllanthus is present in almost all Brazilian territories. The species of this genus are extremely used in folk traditional medicine. The species Phyllanthus amarus Schum. & Thonn. and P. niruri L. have been frequent targets of ethnopharmacological work. However, in the beginning of this century botanic studies were intensified by using molecular markers for unambiguously identification of Phyllanthus species and to indicate the significant differences between the.....
Review Article
Review on Economics of Teff in Ethiopia
Fikadu, Asmiro Abeje*, Wedu, Tsega Desalegn and Derseh, Endalew Abebe
Teff is widely cultivated throughout Ethiopia as a staple cereal crop, which appears in everyone’s dishes of everyday life. With a gluten free and high nutrition values; teff could be the next super-grain and Injera could be the next super-food in the globe. Teff productions in terms of cultivated area and number of producers are incredibly increases over the last 14 years. Teff is the second most important cash crop and generating about 500 million USA dollar incomes per year for local farmers. Apart from this, teff producing farmers are highly depending on the behavior of the other teff producing farmers who spatially closed. Moreover, Teff straw is produced in the largest quantities estimating about 6.93% of the total quantity of cereal crop’s straw produced .....
Short Communication
Research Proposal Self-Management and Commitment for Cancer Patients
In the Netherlands a new concept of health has been introduced by Huber et al. [1]. “Health is the capacity of people to adapt and direct their coping with adversities of life against the background of physical, emotional and social challenges. Being healthy means to be able to adapt to disruptions, show resilience and maintain a balance of refined this balance physically, mentally and socially.” This definition of health has increasingly been adopted in health care and has also entered the Dutch professional profile for nurses [2]. No longer (the concept of ) health is looked upon as a state of complete physical, mental and social well-being as it used to be formulated by the WHO in the nineties, implicating then that many people must be classified as il.....
Mini Review
Risk Factors and Cardiovascular Disease of Urban Population
Docu Axelerad Any and Docu Axelerad Daniel
This article provides an overview of the global burden of cardiovascular disease. It discusses the increase in cardiovascular and other chronic diseases; and then provides estimates of the burden of cardiovascular diseases (CVD) with specific focus on the developing countries and the difference between rural and urban areas, the main differences being the different life-style, each one including specific risk factors. The second part of this article describes the burden of CVD by specific region or ethnic group, the relevant risk factors, and possible strategies for prevention
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