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Mini Review
Nanofibers As Implantable Controlled Release Systems
Serim TM, Amasya G, Eren Boncu T, Sengel Turk CT and Ozdemir AN*
DOI: 10.31031/PSPRJ.2022.02.000549
Abstract
PDF
Full-Text
e-Pub
Controlled release systems that release the active substance at the desired rate for the
desired time have been developed to reduce the incidence of side effects seen in treatment
with classical dosage forms and to increase the compliance of the patients with the treatment
by reducing the frequency of drug use. Controlled release systems are systems in which
the release time and rate are adjusted according to the desired purpose, and the active
substance can be targeted to a specific area of the body. Controlled release systems have many
advantages over conventional systems such as improved efficacy, reduced toxicity, and better
patient compliance
Research Article
A Comparative Assessment on Reprotoxicity of Epicatechin Coated and Citrate Reduced Silver Nanoparticles in Male Mice Reproductive System
DOI: 10.31031/PRM.2022.05.000602
Background: Concerned about the toxic effect of engineered nanoparticles has led to the studies
on repro-toxicity of silver nanoparticles on mice model. The toxicity has been challenged using plant
material that has known protective roles in the living system.
Objectives: The present work aimed to evaluate the repro-toxicity of silver nanoparticles. The idea was
to phyto-fabricate the surface of nanoparticles with epicatechin, a bio-flavonoid, and make a comparative
assessment with citrate-capped particles using male mice reproductive system as a model.
Methods: Silver nanoparticles were synthesized using tri-sodium citrate and epicatechin. The identity
of the particles was confirmed using UV-Vis spectroscopy, DLS and Zeta potential, HR-SEM and EDAX.
Following characterization, bot.....
Mini Review
The Effect of Metformin in Treating Prediabetic Patients
DOI: 10.31031/IOD.2022.05.000622
Prediabetic is a state when the blood sugar level is high but not reaching the diagnostic status of diabetes
mellitus. As defined by American Diabetic Association (ADA), it includes impaired fasting glucose (FBS
5.6-6.9mmol/L) and/or impaired glucose tolerance (glucose 7.8-11.0mmol/L, 2 hours after ingestion of
a 75-g oral glucose load) and/or HbA1c 5.7-6.4%. The risk of progressing to diabetes is greater in patient
with both IFG and IGT compared with isolated IFG or isolated IGT alone [1,2]. Although patients with
prediabetes are asymptomatic, but they carry comparable macrovascular complication and retinopathy
like diabetes mellitus. The progression to type 2 DM may vary from one individual to another depend
on degree of insulin deficiency/resistance along with other risk factors......
Short Communication
Increase of Airway Fungal Co-Infections in Covid-19 Hospitalized Patients: A Brief Report
DOI: 10.31031/GGS.2022.07.000666
The human-to-human transmitted disease, coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread worldwide and affected more than 270
million people, leading to more than 5 million deaths. COVID-19 patients with Acute Respiratory Distress
Syndrome(ARDS) are often admitted to Intensive Care Units (ICUs), frequently receive corticosteroids,
broad-spectrum antibiotics and immunomodulatory agents. An increase of secondary fungal infections
has been described in these patients, which are frequently associated with poor patient outcomes. The
incidence of these infections varies from country to county. Additionally, a variety of fungal species have
been reported around the globe. In this report we will discuss various aspects o.....
Short Communication
Women in Sports: Some Physiological Issues and Gender Differences - A Brief Overview
DOI: 10.31031/RISM.2022.08.000680
Access to participation, training, and competition in sports has historically been denied to women.
But clearly, this view has changed dramatically in recent years. The significant number of women in
competition, coaching, administrative, officiating, ang training positions, is a matter of serious concern.
The present article briefly highlights some important as well as pertinent physiological issues under the
purview of gender along with some suggestive measures in favor of the worldwide movement of sports
for all
Research Article
Corona-Socio-Legal Challenge with Sweden as an Example
DOI: 10.31031/NRS.2022.10.000735
Society is challenged by a virus that threatens humanity, which calls for intervention in private spheres
belonging to different policy areas. As a result, the regulation becomes like a patchwork quilt without
normative consistency. The regulation is ad hoc. Sweden has initially relied on influencing people’s
behavior through norm creation and not legislation, partly being forced to since the constitution does not
leave room for exemption laws in the same way as other countries. When it comes to formulating policy, the
expert authority, Public Health Agency, has a central role. Democracy is replaced by meritocracy. Legality
presupposes legitimacy in order to function. This is a balancing act between formal and substantive legal
certainty. As a general conclusion, legal regulation .....
Research Article
Intracranial Ependymomas in Children the Role of Surgery and the Adjuvant Therapy
Bouaita K*, Atroune L, Selmane T and Habchi N
DOI: 10.31031/SMOAJ.2022.04.000595
The purpose: The management of intracranial ependymomas represents a real challenge and the perfect treatment modality remains controversed. The goal of this study is to highlight the role of tumour removal
and the adjuvant therapy in the survival rate of children presenting with intracranial ependymomas.
Patients and methods: This retrospective study of 56 children presenting with non-metastatic
intracranial ependymomas treated in the period between 2015 and 2020. The age varies from 3 months
to 15 years while the mean age was 8 years. The infra tentorial location was found in 67.8%.
Result: The total resection of the tumour was achieved in only 42.8% of cases, whereas the subtotal
resection was performed in 35.7%. More than 50% of tumours were grade I and II of the Who classificati.....
Mini Review
Development of Polymers Coated with Immobilized Carbonic Anhydrase for CO2 Capture and its Application
DOI: 10.31031/PSPRJ.2022.02.000548
The rocketing CO2 emissions has caused intensified global warming effect to human beings. Although
several approaches have been proposed to reduce atmospheric CO2
emissions, high temperature condition
and high energy consumption make those approaches hard to carried out in industrial application.
Carbonic Anhydrase (CA) catalyzed hydration reactions or aqueous solvents are a potential alternative in
conventional amine-based CO2
capture, for its energy saving and excellent performance. However, free CA
will significantly increase the CA amounts and system cost, as well as decreasing the system efficiency. To
face the mentioned issues, some new methods of immobilization of CA are introduced, which can help to provide new ideas for alleviating greenhouse effect and global warming
Opinion
The Need for a Sustainable Energy Transition in Spain
Pablo Fernandez-Arias* and Diego Vergara-Rodriguez
DOI: 10.31031/COJEC.2022.02.000535
Sustainable development and climate change have gone from being issues to be dealt with
superficially at various international summits to become real problems on which concrete
decisions need to be taken in a short period of time. To give a few figures on the seriousness of
the problem, in the last 50 years, atmospheric CO2
concentration has increased by more than
30%. More than 10% of Green House Gas (GHG) emissions are due to deforestation. These
emissions are similar to those generated by land transport, mainly cars and trucks, which
continue to have a high dependence on traditional fossil fuels. The United Nations Climate
Change conference held in Paris in 2015 set a goal of limiting temperature rise this century to
below 1.5 degrees Celsius, yet 17 of the 18 warmest years in.....
Case Report
Posterior Root-End Resection with Palatal Approach
Juan G Robledo*, Karina I Krasnopolski and Pablo A Rodriguez
DOI: 10.31031/MRD.2022.07.000654
Root-end resection has been defined as “The surgical removal of the apical portion
of a root and adherent soft tissues” [1] thus, is a reliable method of treatment for peri
radicular disease. However, if surgery is indicated in the posterior region, some drawbacks
such as limited access, visibility and anatomical structures induce decision to extraction or
intentional replantation of the tooth. On the palatal side, anatomic considerations should
be evaluated such as root shape, curvatures, location of foramina, fused roots, fenestrations
and even possibility of molars with double palatal root [2,3].
The greater palatine neurovascular bundle (GPB) can be damaged during osteotomy,
root resection or even if a posterior relieving incision is used. Bleeding or paresthesia
could be .....
Mini Review
Innovation in Information Technology for Biomedicine: Ontologies Applied to the Systems Interoperability
Jeanne L Emygdio and Mauricio B Almeida*
Biomedicine is a vibrant field identified with a continuous in innovation. To address the vast amounts of
biomedical data, before innovating, one needs to interoperate data between information systems. Here
we provide a brief account of the pioneer initiatives to foster systems integration
Mini Review
Formation of Rhenium and Tantalum During Electrolysis of Distilled Water Using Tungsten Electrodes and the Expected Isotope Ratio
Kashchenko MP, Pechorsky VI, Kashchenko NM*, Nikolaeva NV and Pushin VG
DOI: 10.31031/AMMS.2022.08.000688
The original installation for plasma electrolysis of water demonstrated, according to [1], an example of the
implementation of low-energy nuclear reactions of the synthesis of chemical elements with low erosion of
electrodes. That is, the initial material for the formation of chemical elements was water, and the product was a solid fraction in the form of a polymetallic powder
Opinion
On The Mechanism of Human Carcinogenesis
DOI: 10.31031/NACS.2022.06.000646
Some bad ideas never die, like drinking and driving, American football, and refusing to
take COVID precautions. Thinking that “incidence rates for cancers overall increase steadily
as age increases” [1] is such an idea. It originated in the 1950’s [2], but has been thoroughly
debunked since then [3,4]. Unfortunately, even the National Cancer Institute continues to
promulgate this myth. Look at the age-distribution of new cancer diagnoses in the 2021
NCI report [1]. It is a bar graph, with each bar representing the number of new cancer cases
per 100,000 people at each age. The cancer incidence rate does increase with age steadily,
meaning regularly or at a relatively unchanging pace, but only from age 20 or so to age 60
or so. After that, the increase in incidence becomes grad.....
Review Article
Is There a Role for Employers to Play in Flexible Working?
This short paper examines the extent to which a range of organizational structure and cultural factors
influence employees’ engagement in Flexible-Working Arrangements (FWAs). Drawing upon a two-year
panel data in Britain, the analysis reveals that, in relation to organizational structural support, enriched
job design and teamwork have a negative impact on employees’ engagement in flextime and job share.
With regard to organizational culture factors, while perceived supervisor’s support enhances employees’
use of various FWAs, work-life balance policy has a positive impact on work-at-home and flextime. Overall, the findings suggest that, while management initiatives targeting a supportive culture likely enhances
employees’ engaging in flexibility, new measures are in need t.....
Opinion
Metallo Nanocomposites in the Matrix of Copolymer of 1-Vinyl-1,2,4, -Triazole with Methacrylic Acid
Sargsyan SH*, Sargsyan AS, Khizantsyan KM, Sargsyan TS, Margaryan KS and Aghajanyan IG
DOI: 10.31031/PSPRJ.2022.02.000547
For medicine, nanophotonics, and catalysis, nanocomposite materials with silver
nanoparticles are necessary and their use in these areas is promising [1]. In modern
chemical science, electrosynthesis and the study of the properties of functional polymers
and nanomaterials based on them are the most rapidly developing areas. Nanomaterials in
medicine are used as antibacterial drugs, biosensors, drug delivery systems, etc. [2,3]. The
process of electrosynthesis of metal-polymer nanocomposites and coatings on pure iron and
steel electrodes was investigated by combining the electrochemical (co)
Short Communication
Antimicrobial Activity of Moringa Oleifera
DOI: 10.31031/NTNF.2022.06.000636
Moringa oleifera is a tree native to the Himalayas but has been introduced to various regions of America, it has antimicrobial, nutritional, antioxidant and therapeutic properties. The objective of this study
was to evaluate the minimum inhibitory concentration of ethanolic extracts of Moringa oleifera leaves on
Staphylococcus epidermidis and Enterococcus faecalis. In the study it was observed that in S. epidermidis
the inhibition was similar in all concentrations, and for E. faecalis inhibition was only observed in the test
with the pure extract. Therefore, it is important to evaluate the inhibitory effect of Moringa oleifera on
other pathogenic strains, as well as the identification of the components that caused the inhibition
Research Article
Mechanism of Temporary Trapped Penis in Circumcision: Some Theories
DOI: 10.31031/RPN.2022.06.000634
Background: There are complications and bleeding differences among obese and buried penis cases.
Bleeding symptoms in these cases may not indicate the amount of bleeding. Continuation of bleeding
without symptoms may bring along other problems such as trapped penis.
Objective: Aim of the study is to draw attention to hematoma and associated trapped penis cases, to
explain the mechanism of trapped penis formation through established theories based on the fluid mechanics, to demonstrate that minor hemorrhages, which occur in patients with the buried penis, may be
incompatible with the amount of bleeding.
Materials & methods: Patients with penile/perineal hematoma that developed after routine ritual circumcision, which was performed under local anesthesia in healthy individuals, were in.....
Opinion
Ignorance, the Hidden Epidemic Habits, Addiction and COVID 19
DOI: 10.31031/FSAR.2022.05.000624
Humanity suffers from epidemics dating back at least 428 BC, where Thucydides describes
for the first time and in detail a plague that struck Athens. For multiple reasons, infectious
epidemics have raged since Greek times, generating more concern and more attention than
other non- infectious but far more deadly epidemics. Perhaps the suddenness of its onset,
the fear of the invisible germ, added to the apocalyptic tone shown by the media and the
confusion of governments when managing infectious epidemics, contribute to this effect. The
COVID 19 epidemic is an excellent sample. However, statistics show that contrary to popular
beliefs, the number of deaths does not place COVID 19 in the number one fatality position.
Even more paradoxical is that the same citizens who are distressed .....
Opinion
Artificial Intelligence and Digital Forensics on Data Governance Breaking Through its Importance to Organizations and its Operations
Bruno Bernardo*, Joao Barroso and Vitor Santos
DOI: 10.31031/FSAR.2022.05.000625
Nowadays, organizations and its businesses are being affected by threats from different
sources, being one of the main, the ever-increasing exponential growth of data, namely the
digital one and the digital disruption [1]. In fact, according to Ragan [2], data, specially the
actionable one, can be considered as the “secret weapon” on the highly dynamic and everinnovative market that characterizes the industry and financial market nowadays [2].
Likewise, the greatest amount of the decisions that organizations make and choose are based
on data [3]. According to Hoppszallern [4], it is unavoidable the importance that information
technology and data governance can have in managing and creating value for organizations.
In fact, Johnston [5] denotes data management as being amongst th.....
Mini Review
Machine Learning: Producing Sophisticated Injection Molded Articles Reliably with New Monitoring Systems
DOI: 10.31031/NRS.2022.10.000734
The most important processing methods for thermoplastics are injection moulding, blow
moulding and extrusion. The diverse and tailor-made properties of specified plastics and
the rapid developments in their processing technology have contributed significantly to the
successful substitution of traditional materials such as metal, wood and glass in various fields
of application.
Even though a rethinking seems to have started recently due to the pandemic situation
[1], in the course of globalization, economic growth and technological progress, it can still be
observed that novel and improved products and processes are becoming established, so that
a consistent change in industry and production can still be observed
Case Report
Gastric Post-Transplant Lymphoproliferative Disorder after Allogenic Stem Cell Transplantation
DOI: 10.31031/GMR.2022.06.000642
Post-Transplant Lymphoproliferative Disease (PTLD) is a well-known complication
following transplantation. Its estimated incidence is 2.5% at 1 year after bone marrow
transplantation [1,2]. PTLD consists of excessive (most frequently B) lymphocyte proliferation
in immunosuppressed patients. Most cases are associated with primary EBV infection
and occur within the first year after transplantation. Staging ranges from plasmocytic
hyperplasia to lymphoma. PTLD can be potentially fatal and treatment is based on reduced
immunosuppression, antiviral therapies, B cell proliferation blockers, chemotherapy and
most recently T-cell therapies [1,3]. We present the case of an 18-year-old young man, who
presented with a 48-hour history of low-grade fever, anorexia, abdominal discomfort and
vom.....
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