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Research Article
Antimicrobial Resistance: The Secret Killer
Alyssa G Hanuschak and Yashwant V Pathak*
DOI: 10.31031/NRS.2021.07.000675
Abstract
PDF
Full-Text
e-Pub
Antimicrobials are medications used to fight common bacteria-caused infections in the body that can
range from minor to severe. Bacteria can mutate and alter its genetic coding to fight the antimicrobials
and ultimately build up resistance making the antibiotic ineffective. Antimicrobial resistance is a problem
faced across the globe and especially in lower income countries. Excessive prescribing, over usage,
incomplete treatment, and lower dosing all contribute to antimicrobial resistance. It is detrimental
because it causes infections that cannot be treated by present antibiotics and it can often be fatal. In
the age of COVID-19, antimicrobial prescribing has increased as an attempt to combat the virus as
proper treatment has not yet been discovered. Various methods can be taken t.....
Review Article
The Implementation of STIFIn Intelligence Test for Students’ Career Planning : An Introduction and Impact of STIFIn Approach
DOI: 10.31031/PPRS.2021.04.000600
This study aims to map students’ intelligence in accordance with the human brain which consists of the sense of thinking, intuiting, feeling, and instinct, through the implementation of the STIFIn approach. This method was also used to help them determine their career path for optimal productivity, because in this era of 4.0 industrial revolution, students are required to upgrade their skills according to their talents and
intelligence. This study therefore uses critical analysis studies in literature review and practical data to expose the importance of STIFIn approach to education counseling for students. The result showed that from students attending to STIFIn test which uncovers that students has a uncover and understanding their potential within their sense such thinking, intuiting.....
Mini Review
Main Precambrian and Paleozoic Mineral Resources of Estonia
DOI: 10.31031/AMMS.2021.06.000639
Estonia is rich in mineral resources. For example, oil shale usage has over 100 years of history and Estonia
holds, the largest in Europe, unused sedimentary phosphate rock reserves, about 3 Billion metric tons
ore (ca 819 Million metric tons of P2
O5
). The phosphate content in fossil shells (phosphorite) ranges
35-37 wt% P2
O5
. These shells are relatively enriched by rare earth elements, where the total rare earth
metals reach 3600ppm. The phosphates are overlain by metal-enriched black shale-graptolite argillite.
Calculated tonnage of elements in the black shale is uranium-5.6656 Million tons (6.6796Mt as U3
O8
),
Zinc-16.5330Mt (20.5802Mt as ZnO), vanadium-47.7538Mt, molybdenum-12.7616Mt (19.1462Mt as
MoO3
) and thorium tonnage in between 0.213-0.254Mt. Estonian oil shal.....
Research Article
Structural Analysis and Thermal Characterization of Composites from HPC And Fe2O3 Nanoparticles
Najlaa D Alharbi* and Nabawia A El Zaher
DOI: 10.31031/NRS.2021.07.000674
In this study, hydroxypropyl cellulose and iron (III) oxide nanoparticles (HPC: Fe2
O3
NPs)composites
were prepared for use in various technological applications. Using X-ray Diffraction Technique (XRD), the
Differential Scanning Calorimetry (DSC) and Thermal Gravimetric Analysis (TG), structural composition
and thermal properties of the prepared nanostructures were examined. Fourier transform infrared TCI,
LOI and HBI indices were also calculated. The observed XRD patterns indicate changes in the crystallinity:
amorphosity ratio and indicate a mixture between the amorphous components of the HPC polymer and
the Fe2
O3
nanoparticles which distinguishes the relationship between the properties of the structure.
Variations have been detected in the glass transition (Tg
) and meltin.....
Case Report
A Late Presenting Tuberculous Dactylitis Case: Choosing the First Line Medical Treatment or going Ahead with Surgical Debridement?
Ramin Zargarbashi, Ehsan Mahmoudi, Kamand Khalaj, Alireza Nezami*, Nesa Milan
DOI: 10.31031/OPROJ.2021.08.000683
Background: Metacarpals and phalanges are rarely affected in extrapulmonary tuberculosis. Tuberculous
dactilytis is defined as infection of metacarpals, metatarsals, and phalanges of hands and feet in
tuberculosis patients. About 85% of affected people with tubercular dactylitis are younger than 6 years
old. As a result of the structure difference between pediatric and adult hand, the disease manifestation
and the subsequent course differ substantially.
Case presentation: A 5-year-old female with isolated metacarpal bone involvement admitted to Children
medical center Hospital, Tehran ,Iran. The patient history indicated a 6 months antibiotic therapy with
no improvement. Based on radiological and sonographical evidences, a surgical intervention was
implemented to remove the necroti.....
Case Report
Road from Hallux Valgus to Familial Glucocorticoid Deficiency (FGD) Diagnosis in a Child: A Case Report
Sadeghi P*, Torshizi MM and Mirzaee HS
DOI: 10.31031/RPN.2021.05.000619
Familial Glucocorticoid Deficiency (FGD) is a rare autosomal-recessive disease. Tall stature and advanced
bone age have been reported among clinical symptoms. This is a report of a 5 year-old girl who was
admitted to the Rheumatology Ward of Bahrami Children’s Hospital for prolonged hallux valgus and
lateral deviation of the hand fingers. Physical examination showed generalized hyperpigmentation and
tall stature and the patient was in the pre-pubertal stage. The cortisol level was lower than normal while
the ACTH level was above the normal limits. A hand X-ray showed a bone age of 9 years and 6 months
.Whole exome sequencing revealed homozygous mutation of the MC2R gene . Endocrine disorders should be considered in cases with uncommon childhood skeletal manifestations
Case Report
Regarding all the Food Allergie
DOI: 10.31031/OPROJ.2021.08.000683
When I, sometime later than first published, read the article in the Telegraph newspaper
describing the work of Professor Gideon Lack. His observations whilst treating patients,
especially very young ones, with emollients to alleviate their skin disorders. He was extremely
thorough and took careful histories to search for the causes of their afflictions, i.e., rashes
and broken skin. The articles is here, https://www.telegraph.co.uk/news/worldnews/
northamerica/usa/1424292/Peanut-allergy-is-linked-to-creams-for-skin-rashes.html and
also available at, https://www.sciencenews.org/blog/food-thought/unexpected-sourcespeanut-allergy. What Prof Lack found very surprisingly was confirmation of some peoples
view that peanut-allergy does in fact occur without prior consumption of peanuts or
.....
Review Article
Improving the Experience of Patients in Contact Isolation by Human Centered Design: A Proof of Concept Study using Patient Journey Mapping
DOI: 10.31031/COJNH.2021.07.000660
Background: Patient information provision about isolation measures is often not standardized. Moreover,
it is unclear what information patients and informal caregivers need to optimize their knowledge and
actual experience of contact isolation. We explored opportunities for improving the experience of patients
in contact isolation from a human-centered design perspective.
Method: We used patient journey mapping and created patient personas based on observations and
interviews with patients and health care workers from a hematology, surgery and acute admission ward
of a Dutch university hospital.
Result: Patients differed in their experience of contact isolation; three personas were identified. The first
liked being in contact isolation, the second had to get used to the measures, t.....
Review Article
Comparison Linear Programming and Improving Shuffled Complex Algorithm for Optimizing Multi Reservoir Systems
Mohsen Najarchi* and Amir Haghverdi
DOI: 10.31031/EAES.2021.08.000689
The increasing growth in the dimensions and complexities of the optimal utilization problem of the
reservoir system, especially hydroelectric power generation systems regarding increasing growth in need
to energy and reduction of fossil fuel resources has reduced the use of classic and conventional methods
and also has led to the use of modern search methods and modern meta-heuristic and evolutionary
algorithms for optimization. In the present study, Shuffled Complex Evolutionary Algorithm (SCE) was
investigated. Then, it was integrated with Differential Evolutionary Algorithm (DE), and Improved
Shuffled Complex Evolutionary Algorithm (SCE-DE) was constructed. To validate and evaluate function
of this algorithm, first, Ackley complex mathematical function and then four other benchma.....
Review Article
Certain Immunity Challenges of Covid-19; Neurotoxic Effects and Immunopsychiatry
DOI: 10.31031/GGS.2021.06.000650
Cytokine Release Syndrome (Cytokine storm) which is an autoimmune reaction or an autoimmune-like
reaction accounts for the complications of COVID-19 and finding immunotherapeutic drugs capable of
blocking the cytokine storm would prevent the morbidity and mortality of COVID-19. Certain groups
of people are recognized to be more vulnerable to the complications of this infection than others. The
Cytokine Release Syndrome (CRS) leads to several neurological conditions even meriting COVID-19 to be
classified as a “neurotoxic illness.” The development and manifestations of neurological complications
of COVID-19 may offer rational support to the novel concept of immunopsychiatry and immunoneuropsychiatry that has the potential to evolve as a subspecialty of general psychiatry. CRS that.....
Case Report
Holistic Centered Treatment Protocol: Evidence Based Novel Treatment for Complex Regional Pain Syndrome-A Case Report
DOI: 10.31031/DAPM.2020.02.000529
a. Holistic Centered Treatment (HCT) protocol is an evidence based novel treatment that is multimodality, non-invasive and drug free used to treat Complex Regional Pain Syndrome (CRPS) and other
forms of intractable chronic pain.
b. HCT consists of laser (3b), Low Level Light Therapy (LLLT), Pulsed Electromagnetic Field
(PEMF), neuroplasticity training, clinical hypnosis, biofeedback-utilizing Heart Rate Variability (HRV),
neurofeedback, vagus nerve stimulation, and breathwork.
c. HCT is a five (5) day protocol followed by a 90-day home program.
d. HCT provided long-term relief and remission for this patient.
e. HCT is an effective treatment option for both type 1 and type 2 CRPS.
Commentary
A New Facet of Symmetry in Chemistry and Biochemistry
Iga DP*, Popescu D and Niculescu VIR
The phenomenon described below concerns molecules having a content of chirality. A new type of
symmetry, complementary to the classical symmetry characterized by a mirror plane of symmetry
is revealed. As the latter generates an enantiomeric image, the plane of symmetry of this new type of
symmetry generates an identical one. The rank of this new plane of symmetry is lower than mirror plane
of symmetry. Arguments from chemistry, biology and practical life are brought in support of this new
facet of chiral compounds
Review Article
Iterative Tomography of Pipes During Operation
Vengrinovich VL, Zolotarev SA* and Zhukov KA
DOI: 10.31031/RDMS.2021.15.000858
Accurate assessment of pipe-wall thickness directly from the pipe’s tomographic images, restored from
only a few X-ray tangential projections, made in a limited observation sector, is discussed. Because the
effects of scattered radiation and beam hardening contribute up to 50% of the primary radiation, ignoring
these effects yields image blurring, strong artifacts, and inaccurate sizing. A computerized technique has
been developed that simulates the contribution of the scattered radiation, beam hardening, and screen
nonlinearity, which is used to correct the projection data. The iterative Bayesian techniques are then used
to reconstruct pipes images from the modified projections, using volumetric and/or hull representation
of the pipe. Using these techniques, the error of the pipe.....
Mini Review
Precision Nutrition, Diet and Gut-Microbiota in Obesity
Olovo CV, Udoekong NS and Akan OD*
Obesity has many angles to its cause. Epidemiological works on diets and diet components show that
obesity and other metabolic diseases are controlled to a large extent with proper diet and lifestyle. Most
works with plant-based diets are noteworthy; they stimulate mechanisms in the host that proffer health,
either through caloric restrictive pathways and the positive stimulation of the gut-brain cross-talks
through fiber fermentation. Due to the heterogeneity of individuals, no one solution is fitting; therefore
dieticians are partnering with other scientists to promote Precision nutrition that considers individual
differences in the host’s gene pool and healthy daily caloric intake. Such patterned diet help prevent
obesity and maintain healthy weights by supplying more nutrition.....
Opinion
Society is Facing Major Challenges Today and they Affect all Actors Worldwide
DOI: 10.31031/NRS.2021.07.000672
Society is facing major challenges today and they affect all actors worldwide: issues
such as climate protection, scarcity of resources, demographic change and upheavals in
the world of work are increasing the pressure, especially in industrial companies, to act
sustainably. In particular, politicians and society now increasingly expect companies to take
responsibility for their actions and their impact on society. This means that companies must
also act responsibly and sustainably “beyond the narrow boundaries of the company” and
“into overlapping socio-political fields of responsibility” [1]. In addition to economic success,
sustainable management also pursues ecological and social goals within the company, in the
corporate environment and in society as a whole
Commentary
Wearable Technology: The Future in Sensory Processing Disorder Intervention
DOI: 10.31031/NRS.2021.07.000671
The use of wearable technology appears to be becoming more prevalent and relevant as
additional advanced tools are being produced. Labis et al. (2015) defined wearable technology
as an innovative trend comprised of mobile computers and sensors that users can interact
with while being worn as part of clothing. People are now able to monitor their physical and
physiological activity levels as a result of these wearable microcomputer systems. For example,
users of the Apple Watch™ can use visual and tactile prompts from the Breathe Application to
synchronize their breath with these sensory cues. Also, the Fitbit™, a microcomputer system
worn on the wrist, can assist wearers of the product in monitoring their ambulation and
mobility. These wearable devices have the potential to pro.....
Opinion
Lockdown Case Applied in West Center in Brazil to Security Against New Coronavirus (Sars-CoV-2)
DOI: 10.31031/NRS.2021.07.000670
Here in central western Brazil, precisely in the state of Mato Grosso, 1.2 million doses of
the Sputnik V vaccine from Russia were purchased in the first quarter of 2021, at a cost of
$10 per dose. This was a measure taken by the Mato Grosso state government, given the lack
of effort by the federal government to deal with the covid-19 case more expeditiously. The
practice of lockdown used here in the Midwest is still timid in relation to other places in the
world. Despite the state of Mato Grosso being one of the epicenters in Brazil of Sars-Cov-2, the
concern of the business class does not help in the fight and confrontation of the virus
Commentary
Make it Add Up, Doc
Did you hear the one about the rheumatologist who was asked to write something for
an accounting journal? Yep, that really happened, and here’s the result. Accounting was one
of the easier classes I took in high school. I’m not even sure why I signed up for it in the first
place. I had zero desire to go into business of any sort, let alone become an accountant. I was
good at math, but that was going to take me into something scientific. A lot of my buddies were
taking accounting, so I did too. I ended up liking the class. Everything was very logical, with
satisfaction to be had in getting the right number in the right column and seeing everything
balance up. I think running numbers makes my brain put out endorphins. I got that from my
dad, a time-study guy at G.M. (they eventua.....
Research Article
Community Service; Transcultural Training, Excellent Service, and Effective Communication in The Context of Interprofessional Collaboration (IPC)
Agussalim*, Asikin M, Rumaseb E, Nasir M, Nuralamsyah M, Podding IT and Edi Hasan
DOI: 10.31031/NRS.2021.07.000671
Culture is the work of a human being that is born along with the creation of man as well as a documented
hereditary in accordance with periodization. Culture is born and develops and changes along with the
changing times. In progress now especially in the development of the region and globalization especially
the era of ASEAN Community certainly needs an accurate understanding will be vary a culture because
certainly all cultural transactions will result in an the tar of different regions, tribes, Nations, countries
as well as transcontinental automated so that it takes the concept of transcultural. Problem solving is in
the improvement of the status of nursing and health services with the aim of increasing order of service,
shortening [1-3]. As well as improving the welfare of publ.....
Research Article
Effects of Anthropogenic Pressures on the Structure of Floristic Components of Mangroves in the Cameroon Estuary
DOI: 10.31031/EIMBO.2021.04.000578
Mangroves are recognized worldwide as one of the most remarkable ecosystems because of their
exceptional biological diversity whose origins are terrestrial, marine or intertidal. Mangroves play
a role in coastal protection, biodiversity maintenance, flood mitigation, storm protection, pollution
control, and coastal erosion reduction. This study was conducted with the aim of determining the
impact of anthropogenic activities on the structure of some biological components in the mangroves of
the Cameroon Estuary. The work took place at seven sites in the study area, spread across the Littoral
and Southwest regions from February to December 2019. Inventories were carried out on all trees of
at least 1cm in diameter in plots of 2500m2
(50m x 50m). Species were identified and counted, .....
Review Article
Applications of Targeted Protein Degradation in Drug Discovery
DOI: 10.31031/ACSR.2021.02.000541
Proteostasis is a process that controls protein abundance in living cells in order to maintain healthy
proteome at both cell and organ levels. In eukaryotes, the ubiquitin-proteasome pathway and the
lysosomal network are two main systems for this purpose. Since the first attempt was tried to design
drugs using protein degradation principles in 2001, rapid progress has been made over the past 20 years.
In this review article, we will summary a few approaches to design protein degradation drugs, including
PROTACs, Homo-PROTACs, Opto-PROTACs, PHOTACs, CLIPTACs, ATTEC, AUTACs, as well as LYTACs, and
briefly discuss their current progression
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