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Latest Articles

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Mini Review

Adomet Synergistically Enhances the Chemotherapeutic Action of Cisplatin and Improves Drug Efficacy in Jhu-Scc-011 Laryngeal Squamous Cell Carcinoma

Laura Mosca, Martina Pagano, Francesca Vitiello, Concetta Paola Ilisso, Alessandra Coppola, Luigi Borzacchiello, Giovanna Cacciapuoti and Marina Porcelli*

Novel Approaches in Cancer Study

DOI: 10.31031/NACS.2020.05.000603

Laryngeal squamous cell carcinoma (LSCC), is characterized by an aggressive clinical behavior and lack of specific targeted therapies. Thus, novel therapeutic approaches that take advantage of the combination of anticancer natural compounds and chemotherapeutic molecules currently used for LSCC are strongly necessary. S-adenosyl-L-methionine (AdoMet), the main biological methyl donor, is well known for its antiproliferative, proapoptotic and antimetastatic effect in several type of human cancer. In the current study we investigated the antitumor activity of AdoMet in combination with cisplatin (cDDP), an agent usually used in cancer therapy of LSCC, in JHU-SCC-011 cells and we explored the underlying mechanisms. We found that the combination of 200μM AdoMet/0.18μM cDDP syner.....

Research Article

The Effect of Rhizophora racemosa (Red Mangrove) Leaves and Root-Bark on Testosterone and Oestrogen Levels in Blood Serum of Broilers

Shidi SA*, Wekhe SN, Amakiri AO and Owen OJ

Clinical Research in Animal Science

An experiment was conducted in the Teaching and Research Farm of the RSUST. Port Harcourt to evaluate the effect of Rhizophora racemosa (Red Mangrove) on testosterone and oestrogen levels in blood serum. Using a 2x3 factoral arrangement in a completely randomized design experiment. The birds were randomly allocated into seven treatment groups. A, B1, B2, B3, C1, C2, and C3 of 15 birds per group. All groups were replicated thrice with five birds. Pulverized R. racemosa leaf and root-bark was administered to the birds faded levels of 70, 80 and 90 grams for both leaf and root-bark. The highest levels of inclusions (90gm) were used. The experiment lasted eleven weeks. Results obtained showed that R. racemosa significantly (P<0.05) increases testosterone and Oestrogen level in broilers.

Research Article

The Implementation of Animal Assisted Therapy Programs in Substance use Disorders

Abel Baquero E*, Martin JR and Montolio MM

Psychology and Psychotherapy: Research Study

DOI: 10.31031/PPRS.2020.04.000577

Animal Assisted Therapy (AAT) is presented as a complementary program that, together with rehabilitation treatment, favors the clinical evolution of the patients who participate in it. The integration of AAT in the healthcare and health field has been increased in recent years; highlighting the growing interest in AAT programs, along with numerous studies that examine the benefits and efficacy of different therapeutic approaches with animals [1,2], after different and novel pilot experiences in substance use disorders [3], it seems that TAA is an intervention approach with utility in the rehabilitation processes of people with disorder substance use.

Short Communication

Ornamental Plants Help to Beautify your Surrounding and Liberate Oxygen

Manju Das, Biswas SK, Zaman S, and Mitra A

Modern Concepts & Developments in Agronomy

DOI: 10.31031/MCDA.2020.07.000651

Utility of keeping ornamental plants not only beautify your place of residence but helps to add oxygen to purify air. Plants absorb more carbon-di-oxide during daytime and prepare their own food. Oxygen releases to the surroundings and helps to breathe properly. Dates back from Mesopotamian era human settlement has a tendency to beautify their surroundings with ornamental plants. (“First use of orna-mental plants in the history of urbanization” by Osman Zeybek [1]). Different chrome in leaves are quite attractive. It attracts human eyes too. Keeping ornamental plants and decorate is a natural tendency of human habitation.

Mini Review

Fixed, Random and Mixed Statistical Models for Field Experimentation

Robson da Silva Ramos*, Fabian Santana Silva and Álvaro Eugênio Duarte de França

Modern Concepts & Developments in Agronomy

DOI: 10.31031/MCDA.2020.06.000650

One of the stages of the experimental planning phase is the determination of statistical models. To do this, it is important to understand the nature of the sources of variation. The determination of fixed and ran-dom factors auxiliary directly in the previous choice of statistical models, as well as in the experimental design. The prior choice of statistical models in field experiments is important for otimizate representa-tiveness and accuracy of the data.

Case Report

Chronological Experience of Alice in Wonderland-Like Visual Impairment Due To Correlating Physical Abuse till Teenager Age

Bittmann S*, Alieva EM, Villalon G and Luchter E

Research in Pediatrics & Neonatology

DOI: 10.31031/RPN.2020.04.000594

Alice in Wonderland Syndrome (AIWS) was named after Lewis Carroll’s description in his novel. It was in 1955 that John Todd, a psychiatrist, first described this entity. Todd described it as “Alice’s Adventures in Wonderland” by Lewis Carroll. The author Carroll suffered from severe migraine attacks. Alice in Wonderland Syndrome is a confusing state of seizures that affect visual perception. AIWS is a neurological form of seizures that affect the brain, causing impaired perception. The patients describe visual, auditory and tactile hallucinations and perceptual disorders. The causes of AIWS are not yet known exactly. Cases of migraines, brain tumors, depression episodes, epilepsy, delirium, psychotropic drugs, ischemic stroke, EBV, mycoplasma and malaria infections correl.....

Research Article

Correlation between Limited Prosocial Emotions and Empathy in Adolescents Clinical Population

Serment M, R de la Peña F* and Delgado AR

Research in Pediatrics & Neonatology

DOI: 10.31031/RPN.2020.04.000595

The present study aims to determine the correlation between Limited Prosocial Emotions (LPE) specifier for disruptive behavior disorders and the cognitive and affective subtypes of Empathy in a clinical population of adolescents in Mexico City. Sample was integrated with 49 participants between 13 and 18 years old from the Clínica de Adolescentes, an outpatient service of the Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz. All adolescents included, received LPE specifier diagnosed by certified psychiatrist using a categorical and dimensional instrument. The Global Empathy Scale parent/tutor and self-report versions were used to evaluate cognitive and affective empathy subtypes. The results showed an inversely correlation (r=-0.54, p<0.05) between the severity.....

Research Article

Acute Abdomen as a Presentation of Covid 19 in Children: Our Early Experience

Samiul Hasan*, Ayub Ali and Umama Huq

Research in Pediatrics & Neonatology

DOI: 10.31031/RPN.2020.04.000596

Background: COVID-19 is currently a public health emergency around the world. Increasingly more people are being identified with this deadly viral disease. Though children experience a milder disease course, severe and life threatening disease has also been reported. An atypical presentation may delay the diagnosis, isolation, and treatment. The aim of this study was to share our experience of atypical presentation of COVID-19 cases as acute abdomen in children.Method: We retrospectively reviewed data of all children diagnosed to have COVID 19 in our department between April to June 2020. Epidemiological & clinical data of children presented with acute abdomen were retrieved and placed in Microsoft Excel 2016. The data were then analyzed and literature reviewed.Result: Tota.....

Case Report

Ectopic Hydatidiform Mole a Case Report

Nora Awad Elkarim Bashir Mohamed*, Laila Moharram and Hedaya Atalla M Alblewi

Novel Research in Sciences

DOI: 10.31031/NRS.2020.4.000586

Background: The incidence of ectopic Hydatidiform mole is presumed to be 1.5 in a million, Making suspicion of the diagnosis less likely. It is important to differentiate between a conventional ectopic and a molar ectopic gestation as they both have the same clinical presentation; however histopathologic fea-tures are different. Reaching the proper diagnosis helps in appropriate follow up and counseling.Case Report: A 32 years old, Gravida 5 para 4, presented to the emergency department with 5 weeks plus 6 days amenorrhea and lower abdominal pain. In view of a high Quantitative beta human chorionic gonadotropin (30870 mIU/L), an empty uterus and a complex mass in the left tube 9x8 mm, the patient had laparotomy with left salpingectomy, histopathology of the specimen reported complete mole.....

Review Article

Recent Insights into β-Carboline Alkaloids with Anticancer Potential

Lakshmi Manasa K, Swetha Yadav S, Srikanth D, Narayana Nagesh* and Malli-ka Alvalaa

Modern Approaches in Drug Designing

DOI: 10.31031/MADD.2020.03.000554

Development of nature inspired new drug molecules through medicinal chemistry approach has a profound success on drug discovery. Efforts of chemists have succeeded in developing semi- synthetic derivatives to dominate the authentic natural product in terms of drug-likeness properties include increased potency, reduced toxicity, and patient compliance. β-carbolines a family of indole-based alkaloids, remained as a privileged scaffold to exhibit anticancer effects through numerous mechanisms. This review inclines the readers towards the ongoing developments (2017-2019) on cytotoxic effects of β-Carboline with a significance on structure based rational drug design, multiparameter lead optimization strategies, relevant SAR studies of this particular fr.....

Research Article

What Would it Mean if White Sharks, Carcharodon Carcharias, Possessed Disconjugate Optokinetic Stimulation?

Erich K Ritter* and Andreas Dellios

Examines in Marine Biology & Oceanography

DOI: 10.31031/EIMBO.2020.03.000570

Disconjugate eye movements are a feature of some animal species, but it is unknown whether white sharks, Carcharodon carcharias, possess independent eye moments, as well. Here, the question of what it could mean if they exhibited this ability is discussed. Video evidence shows the possibility of independent eye movements with a white shark looking at two distinct targets aimed at them consecutively. Different interpretations of the videos core frames are discussed with disconjugate optokinetic stimulation as the most highly advanced possible explanation of this observation. Such an ability would enable a white shark to scan its entire visual field and confer an advantage in terms of being able to observe two prospective food sources on either side of its head, allow.....

Case Report

EUS-Guided Micro-Forceps Biopsy for the Diagnosis of Lymphoma: A Case Series

Arcelia Guerson Gil*, Qiang Liu and Sammy Ho

Gastroenterology: Medicine & Research

DOI: 10.31031/GMR.2020.05.000601

EUS-guided tissue acquisition has evolved into an effective endoscopic technique to diagnose lymphoma. Historically, EUS-guided fine needle aspiration (FNA) has been used with suboptimal diagnostic accuracy [1]. EUS-guided fine needle biopsy (FNB) with core specimen acquisition has subsequently emerged as a potentially superior diagnostic procedure [2]. More recently, the Moray micro-forceps device (U.S. Endoscopy, Mentor, Ohio), a through-the-needle biopsy forceps, has been approved for EUS-guided tissue acquisition of cystic lesions. In this case series, we explored the use of the micro-forceps to aid in the diagnosis of suspected lymphoma.

Mini Review

The Economic Impact of the COVID-19 Virus and Considerations of the United States Unified Budget Act

Paul F Gentle*

Strategies in Accounting and Management

The COVID-19 virus impacts many facets to American Society. Included in this article is discussion of the effects of the Unified Budget Act (UBA), in how future liabilities may not be considered enough, by political actors. This article explains the influences of COVID-19 virus on federal tax revenues, and the debt to GDP ratio.

Mini Review

The Economic Impact of the COVID-19 Virus and Considerations of the United States Unified Budget Act

Paul F Gentle*

Strategies in Accounting and Management

Editorial

Can Low Intensity Resistance Training with Blood Flow Restriction be used for the Management of Lateral Elbow Tendinopathy?

Stasinopoulos Dimitrios*

Research & Investigations in Sports Medicine

DOI: 10.31031/RISM.2020.06.000647

Lateral elbow tendinopathy (LET) commonly referred to as tennis elbow or lateral epicondylitis is one of the two most common tendinopathies of the upper extremity among athletes and non-athletes. Although the diagnosis of LET is simple, the ideal management for the rehabilitation of LET does not exist. A conservative approach is advocated by many physicians. Therefore, physical therapy is usually recommended. A plethora of physiotherapy modalities has been recommended for the management of LET such as heavy-slow resistance exercise, manual techniques, physical agents, external support and soft tissue manipulation. Such a plethora of techniques suggests that the ideal management strategy is unknown, and further research is required to find the most ef.....

Mini Review

Temperature Influence on the Process of the Gelation of the Engine Oil

Krzysztof Biernat* and Monika Ziółkowska

Progress in Petrochemical Science

DOI: 10.31031/PPS.2020.03.000565

The article discusses the process of gelation of engine oils and its influence on exploitative properties. The results of research on the propensity of engine oils for gelation at low and high temperatures are presented. The influence of various factors such as: base oil, vegetable oil, FAME and soot on the gelling process was determined. It was found that the cause of gelation of oils, depending on the operating conditions, oil components, may be several factors independent of each other. These factors are discussed in the article

Opinion

Evaluation of Conventional Antibiotics and Ocimum gratissimum /Metallic Sulfur Mediated Nanoparticles Against Endophytic Leguminous Bacteria and Selected Clinical Isolates

Oludare Temitope Osuntokun* and Olayemi Stephen Bakare

Determinations in Nanomedicine & Nanotechnology

The purpose of this research work is to isolate, identify and characterize organisms from in the endosphere of leguminous plants, determine the susceptibility pattern of endophytic bacteria to two sulfur nanoparticles synthesized in the presence and absence of Ocimum gratissimum, to compare the antibiotic susceptibility assay of isolated bacteria using Cephalosporin (oxoid) and multiple susceptibility disc.

Case Report

An Unusual Case of Rectal Bleeding due to Metastasis from Cholangiocarcinoma

Arcelia Guerson Gil*, Qiang Liu and Sammy Ho

Gastroenterology: Medicine & Research

DOI: 10.31031/GMR.2020.04.000599

Cholangiocarcinoma (CCA) is a rare, yet aggressive form of cancer that can originate from the epithelium to anywhere along the bile ducts (BD). Depending on the locations of the CCA, the treatment, prognosis, and diagnosis can be greatly impacted. The primary risk factors are sclerosing cholangitis and choledochal cysts. Anatomically, CCA are classified as intrahepatic (IH) and extrahepatic (EH). EH further divided into distal and perihilar. These subtypes have common features but also important differences that affect the pathogenesis and outcome. Histologically, a great majority of these (90%) are adenocarcinomas with the remainder being mostly squamous cell carcinomas. It is possible to support a diagnosis of malignant biliary epithelium through immunohistochemical staining. Specificall.....

Short Communication

The Effect of Extracorporeal Albumin Dialysis (ECAD) on Pruritus Using MARS Versus New Adsorbent Recirculation (OPAL)

Hartmut Schmidt, Christian Wilms, Hans Ulrich Gerth, Michael Hinz, Sebastian Koball, Alexandra Rivera Luna, Victoria Rivera Luna, Claudia Pfensig, Adrian Dominik, Andreas Kortgen, Christoph Sponholz, Matthias Dollinger, Sebastian Klammt, Kristin Bruederle

Gastroenterology: Medicine & Research

DOI: 10.31031/GMR.2020.04.000600

Extracorporeal Albumin Dialysis (ECAD) is a therapy option for pruritus in cholestatic liver disease. The aim was to evaluate the feasibility for ECAD using two different devices. A subgroup with intractable pruritus of a prospective randomized crossover study in liver patients was analyzed. Randomly subjects received either MARSTM first and new HepalbinTMCluster12 albumin dialysis (OPALTM) second or vice versa. Visual Analogue Score, total bile acids as well as albumin binding function were measured before and after each treatment. 8 subjects suffering from cholestatic liver disease and pruritus were enrolled. Subjects in both arms were comparable. Albumin dialysis could reduce albumin bound toxins, the binding function of patient’s albumin improved in OPAL, but not in MARS. Which one o.....

Opinion

On Synovial Fluid Cristallography Training for Arthrocentesis Performing Physicians

Artem A Popov*, Olga V Teplyakova, Galina I Shlykova and Тatyana G Dotsenko

Orthopedic Research Online Journal

DOI: 10.31031/OPROJ.2020.07.000663

Synovial Fluid (SF) investigation should be a routine procedure for practitioners who perform arthrocentesis [1]. The most important reason to perform arthrocentesis is to check for joint infection, crystal deposition, autoimmunity, trauma or malignancy, as timely identification, treatment of a patient with septic arthritis are of paramount importance to a favorable clinical outcome. Also, arthrocentesis is indicated to gain diagnostic information through synovial fluid analysis in the case of a monoarticular or polyarticular arthropathy of unclear etiology presenting with joint pain and swelling [1]. Due to quality of relevant information obtained, the synovial fluid analysis has been referred as a “liquid biopsy” of the jo.....

Research Article

Movement Variability in Gait: Low Back Pain Kinematics and Chaos

Christos Tsigkanos*, Theano Demestiha, Chara Spiliopoulou and Georgios Tsigkanos

Orthopedic Research Online Journal

DOI: 10.31031/OPROJ.2020.07.000664

Introduction: Kinematic analysis has been a dominant tool for addressing the neuromuscular and proprioceptive alterations that occur in Low Back Pain (LBP) patients. Movement variability is a crucial component of this analysis. During the past years, a promising approach is the application of non-linear indices.Objective: The aim of the study was to compare movement variability, as expressed mainly by non-linear indices, at the pelvis and lumbar between LBP patients and healthy participants during gait. A. Participants and setting: Sixteen (16) LBP patients and thirteen (13) healthy control subjects (non-athletes) participated in the study. Participants walked on a treadmill at different walking conditions while recorded by a 6-infrared camera optoe.....

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Editor In Chief

Hirotada TSUJII

Ph.D in Agriculture from Faculty of Agriculture, Tohoku University

Approaches in Poultry, Dairy & Veterinary Sciences

Maria Kuman

Research Professor, PhD, Holistic Research Institute

Advances in Complementary & Alternative Medicine

Tomasz Karski

MD PhD, Professor, Vincent Pol University

Orthopedic Research Online Journal

Jiexiong Feng

Professor, Chief Doctor, Director of Department of Pediatric Surgery, Associate Director of Department of Surgery, Doctoral Supervisor Tongji hospital, Tongji medical college, Huazhong University of Science and Technology

Research in Pediatrics & Neonatology

Muhammad Atiqullah

Senior Research Engineer and Professor, Center for Refining and Petrochemicals, Research Institute, King Fahd University of Petroleum and Minerals (KFUPM), Dhahran, Saudi Arabia

Research & Development in Material Science

Ian James Martins

Fellow of International Agency for Standards and Ratings (IASR), Edith Cowan University, Sarich Neuroscience Research Institute

Advancements in Case Studies

Thomas F George

Chancellor-Wisconsin–Stevens Point, provost at Washington State University; Professor emeritus-University of Missouri–St. Louis; dean of science at SUNY-Buffalo

Annals of Chemical Science Research

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Zhengcai Lou

Wenzhou Medical University, China
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Fooyin University, Taiwan
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Saglik Bilimleri University, Turkey
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Vincent Pol University, Poland
Thamil Selvam

National Defence University of Malaysia, Malaysia
Tarik Baykara

Dogus University, Turkey
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Hope College, USA
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Russian Academy of Sciences, Russia
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Umm Al-Qura University, Saudi Arabia
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City University of New York, USA
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Hebei Normal University, China
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Alexandria University, Egypt
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Indian Institute of Technology Kharagpur, India
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Council for Agriculture Research and Analysis of Agri Economy (CREA), Italy
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King Fahd University of Petroleum and Minerals, Saudi Arabia
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King Abdulaziz University, Saudi Arabia
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University of Oregon, USA
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University of Edinburgh, Scotland
Maria Kuman

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Islamic Azad University Central Tehran Branch, Iran
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Paeditric Hospital "Giovanni XXIII", Italy
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University of Nicosia, Cyprus
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Beijing Normal University, China
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National Center for Global Health and Medicine, Japan
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Molloy College, USA
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Federal University of Piauí, Brazil
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Krankenhaus Nordwest Hospital, Germany
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Laval University, Canada
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UPMC Hamot Neuroscience Institute, USA
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Welcome to

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We at Crimson Publishing are a group of people with a combined passion for science and research, who wants...

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Adomet Synergistically Enhances the Chemotherapeutic Action of Cisplatin and Improves Drug Efficacy in Jhu-Scc-011 Laryngeal Squamous Cell Carcinoma

The Effect of Rhizophora racemosa (Red Mangrove) Leaves and Root-Bark on Testosterone and Oestrogen Levels in Blood Serum of Broilers

The Implementation of Animal Assisted Therapy Programs in Substance use Disorders

Ornamental Plants Help to Beautify your Surrounding and Liberate Oxygen

Fixed, Random and Mixed Statistical Models for Field Experimentation

Chronological Experience of Alice in Wonderland-Like Visual Impairment Due To Correlating Physical Abuse till Teenager Age

Correlation between Limited Prosocial Emotions and Empathy in Adolescents Clinical Population

Acute Abdomen as a Presentation of Covid 19 in Children: Our Early Experience

Ectopic Hydatidiform Mole a Case Report

Recent Insights into β-Carboline Alkaloids with Anticancer Potential

What Would it Mean if White Sharks, Carcharodon Carcharias, Possessed Disconjugate Optokinetic Stimulation?

EUS-Guided Micro-Forceps Biopsy for the Diagnosis of Lymphoma: A Case Series

The Economic Impact of the COVID-19 Virus and Considerations of the United States Unified Budget Act

The Economic Impact of the COVID-19 Virus and Considerations of the United States Unified Budget Act

Can Low Intensity Resistance Training with Blood Flow Restriction be used for the Management of Lateral Elbow Tendinopathy?

Temperature Influence on the Process of the Gelation of the Engine Oil

Evaluation of Conventional Antibiotics and Ocimum gratissimum /Metallic Sulfur Mediated Nanoparticles Against Endophytic Leguminous Bacteria and Selected Clinical Isolates

An Unusual Case of Rectal Bleeding due to Metastasis from Cholangiocarcinoma

The Effect of Extracorporeal Albumin Dialysis (ECAD) on Pruritus Using MARS Versus New Adsorbent Recirculation (OPAL)

On Synovial Fluid Cristallography Training for Arthrocentesis Performing Physicians

Movement Variability in Gait: Low Back Pain Kinematics and Chaos

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