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COVID-19 (Corona Virus Disease)
Crimson extends its support to scientists, health workers, publishers, funders, policymakers, and government officials for their efforts in mitigating the impact of this global health crisis.
We encourage our authors to share their trusted information and analysis on COVID-19 diagnosis, treatment, prevention & further research.
We ensure that the latest research articles, collections, and commentaries are made available for open access on a fast-track basis.
Opinion
SARS-CoV-2: Complications after Recovering Covid-19 and its Precautions
Afsar S Pathan and Pankaj G Jain*
DOI: 10.31031/MAPP.2022.03.000551
Abstract
PDF
Full-Text
e-Pub
COVID-19 is largely a viral infection of the respiratory tract caused by SARS-CoV-2. The
vast spectrum of clinical signs associated with the involvement of numerous organs in SARSCoV-2 patients is now considered a systemic infection due to the vast spectrum of clinical
signs associated with the involvement of numerous organs in SARS-CoV-2 patients. COVID19’s immediate consequences are well known and frequently associated with a greater risk
of death. However, delayed or long-term COVID-19 problems are becoming more prevalent
and are associated with greater morbidity
Research Article
What Is the Role of Gastrointestinal Symptoms in Covid-19?
Pedro Ferraz Fernandes1*, Clara Gomes Madureira, Yasmin Cáfaro Abud1 and Ethel Zimberg Chehter2
DOI: 10.31031/GMR.2022.06.000650
Objective: To describe the role of Gastrointestinal (GI) symptoms as a diagnosis and/or prognosis in
COVID-19.
Method: Narrative literature review performed in March 2020 following the PRISMA method.
Results: A total of 285 articles were found in Pubmed and Scielo databases, of which 260 were excluded,
25 analyzed in full and nine included in the review. Gastrointestinal symptoms are very prevalent,
present in 58.91% of surveyed patients. The most prevalent symptom was nausea, present in 34.41% of
patients with gastrointestinal symptoms, followed by vomiting (22.20%) and diarrhea (15.69%).
Conclusion: Considering the scarcity of information produced so far, was reached the conclusion that
the role of gastrointestinal symptoms as a diagnosis/prognosis in COVID-19 cannot be establish.....
Research Article
Use of Telemedicine During the Second Covid Pandemic Wave of October 2020 in a Tertiary Referral Hospital in Switzerland
Emmanuel Haefliger*, Philipp Suter, Gael Grandmaison and Daniel Hayoz
DOI: 10.31031/TTEH.2022.03.000562
Covid-19 posed major problems for health systems and hospitals, which suddenly had to deal with
significantly larger patient flows. Each hospital has responded differently, with telemedicine proving a
viable option. Patients were discharged earlier and further monitored by telemedicine; the emergency
departments used telemedicine as a triage tool, or consultations were conducted via telemedicine
applications. We conducted a retrospective descriptive study analyzing the satisfaction of telemedicine
follow-ups of COVID-19 positive patients discharged from hospitalization. Physicians followed up the 24
patients via telemedicine, and 21 questionnaires were completed and analyzed, based on the total of 55
performed consultations. In general, the patients were delighted with the follow-up.....
Review Article
Exposure To Ambient Nanoparticles And COVID-19 Infection
Epidemiological studies have shown that respiratory viral infections have been associated with air
pollutants exposure. So that, the increased incidence of SARS-CoV-2 infection and mortality from
COVID-19 is related to exposure to urban air pollution. In addition, changes in meteorological parameters
have been involved in air pollution and the incidence and development of COVID-19. Although, the
molecular mechanisms by which exposure to air pollutants affects COVID-19 are still unknown and it is
not yet clear how the virus is transmitted from one sick person to another and why it is so transmissible.
Viruses can be probably transmitted through speech and exhalation aerosols. Findings show that SARSCoV-2 aerosol transmission is possible. Spike (S) proteins of SARS CoV-2 determine tiss.....
Opinion
Public Health, India and COVID 19
Public health has numerous definitions, but in its most basic form, it refers to improving
the health of a population through planned and coordinated community engagement. These
activities include contact tracing, health awareness, vaccine delivery, and other COVID-19-
related activities in which health professionals are actively involved. Another perspective is
more intellectual and is best described by the term “population health.” It is a phrase used
to describe a population’s health state. The goal of public health, in this case, is to capture
and portray a population’s health status as determined by current indicators. The term
“population health”
Short Communication
The Health and can Overcome this Infection. The Author Presents Some Data of Covid-19 from the Jan, 2020 till Coronavirus (SarsCov-2) with Special Emphasis on Diabetes Mellitus (DM): A Short Communication
DOI: 10.31031/AMMS.2022.02.000549
The recent emergence of the novel, pathogenic SARS-coronavirus 2 (SARS-Cov-2) in China and its rapid
national and international spread create a global health crisis. Angiotensin-Converting Enzyme 2 (ACE2)
is the cellular receptor for SARS coronavirus (SARS-CoV) and the new coronavirus (SARS-CoV-2) causing the serious epidemic COVID-19. The novel SARS-CoV-2 is a warning for the metabolic disorder patients especially diabetes mellitus due to weak immunity system of the patient’s body and thereby more
susceptible to coronavirus infections. The diabetic patients protecting against COVID-19 include social
distancing of at least six feet, use of face masks, washing hands often with soap or sanitizer, use of water for at least 20 seconds and making sure you are up to date with vaccinations .....
Opinion
Acute Microangiopathy: Key Piece in Covid-19: Acute, Sub-Acute and Chronic
DOI: 10.31031/SMOAJ.2022.04.000598
We know that COVID-19 and its causal agent, SARS-CoV-2, have caused unprecedented
morbidity and mortality since 2019, not only in its acute form, but also in its subacute and
chronic forms. Where the cellular and endothelial damage, caused by the dysregulation of the
immune response, with the production of a cytokine storm, and a pro-coagulant state induced
by the virus, favor the development of sequelae, within which we can list an endless number:
fatigue, precordial pain, cognitive, cardiac, digestive disorders, etc. that reduce the quality of
life of patients [1]. We have learned and unlearned a lot during all this time and originally
COVID-19 was considered a respiratory disease, today we know that it is a systemic disease,
where endothelial damage is a key piece: this endothel.....
Research Article
Pulmonary Thromboembolic Disease in COVID-19 Hospitalized Patients on CT Pulmonary Angiography-Prevalence, Pattern of Disease and Relationship to CT Scan Severity Score (CTSS)
Ramezan Jafari, Fatemeh Dehghanpoor* and Fatemeh Salmanzadegan
Aims: Covid 19 is a multisystem disease that varies from mild to very severe and is fatal in different
individuals. The exact cause of the deterioration of the disease in some people is not completely known,
but various studies have shown that the risk of venous arterial embolism is higher in these patients for
various reasons, and one of the reasons that worsen the clinical course and increases mortality in these
patients, Pulmonary Emboli (PE). Due to the non-specific and non-diagnostic nature of clinical signs and
laboratory tests (d-dimer) for the diagnosis of PE in patients with covid-19 and also the non-specificity of
the findings in contrast-free CT, there is a possibility of delay in the diagnosis of PE. Since early detection
of PE treatment and prevention of PE in high-risk.....
Review Article
The Relationship of Hematological Disorders in SARS-CoV-2 Patients with Intensive Care Needs and Survival
Habip Gedik*, Bilgehan Irmak and Osman Yokus
DOI: 10.31031/CJMI.2022.05.000622
Objective: It was aimed to retrospectively examine the clinical and survival results of patients who were
consulted with the hematology clinic due to hematological disorders related to severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2).
Materials and methods: In this study, the data of patients who were hospitalized and consulted to the
hematology clinic due to hematological disorders related to COVID-19 infection diagnosed by radiological
findings and/or PCR results in the Ministry of Health Istanbul Training and Research Hospital between
May 21, 2020, and April 1, 2020, were evaluated, retrospectively.
Results: Of the 48 patients evaluated in the study, 25 (52%) were female and 29 (60%) were 60 years old
and above. Leukocytosis in 5(10%) patients, leukopenia in 19 (39%).....
Short Communication
Rapid and Sensitive SARS-CoV-2 Detection in Saliva Samples; Basis for a High Throughput Screening
We used a commercially available colorimetric enzyme mix to perform Reverse Transcribed LoopMediated Isothermal Amplification (RT-LAMP) for detecting SARS-CoV-2 on saliva samples without a
previous RNA purification step. We describe our optimization of the LAMP assay that enabled simple, fast
and sensitive detection in any saliva sample. Adding Chelex-100 and SDS to saliva samples, we achieved
97% efficiency in the detection of SARS-Cov-2 with spike-in saliva samples and 100% in a small sample of
saliva from infected patients. This method is meant to be the basis for high throughput screening, as well as a feasible and cheap method for any laboratory
Opinion
The Reemergency of Swine Coronaviruses in the Framework of the Sars-Cov-2 Pandemic
DOI: 10.31031/CRAS.2022.02.000528
The emergence of SARS-CoV-2 on the human health with more than two thirds of the world
population in quarantine, six million of dead as well as the unpredictable economy impact
have popularized the morphology of the SARS-CoV 2 virus, the clinical and epidemiological
characteristics of the COVID 19 as well as the popularity of human physicians, virologists
and epidemiologists with limited experience in the surveillance and control of the CoVs.
“Never in the history of humanity have such drastic interventions into the lives of populations
occurred in the name of health on such a scale and in a short period of time” [1]. Conversely,
veterinarians, particularly, swine practitioners, since 1946, the first description of porcine
transmissible gastroenteritis
Case Report
COVID Pneumonia with Typhoid Versus Calcular Cholecystitis; Escalation Drama among Internists and Surgeons; Seriousness and Interpretation: A Case Report in Surgery, Infectious Diseases, Chest, and Critical Care Medicine
DOI: 10.31031/SMOAJ.2022.04.000597
Rationale: Accurate, précised, and correct diagnosis is one of the most important cornerstones in
clinical medicine. Pandemic COVID-19 virus infection represents the top widely spread disease in the
current time. Acute cholecystitis is a common surgical disease. There is no more difficulty in its diagnosis.
Typhoid fever is considered a serious multisystemic infection. Sometimes, the physician, surgeon, and
internist deal with the patient based on his specialty view neglecting the other specialties. Undoubtedly,
differential diagnosis is a base of medicine.
Patient concerns: A 54-year-old, housewife, married, Egyptian female patient was initially diagnosed
with acute calcular cholecystitis neglecting COVID-19 pneumonia with typhoid fever.
Diagnosis: COVID pneumonia with typhoid fe.....
Commentary
Renewable Energy Challenges and Opportunities in the COVID-19 Pandemic
Mochamad Denny Surindra* and Wahyu Caesarendra
Nowadays, the world is starting to enter a new normal era which requires people to change
new habits and behaviors based on adaptation to cultivate clean living behavior according to
health protocols to continue carrying out normal activities to prevent the transmission of
Covid-19. The Covid-19 pandemic, followed by changes to the rules, certainly has a broad
impact on many sectors. In fact, the changing community activities have made the business
world quiet, such as in the tourism sector, online transportation, retail sales and of course
in the energy sector. The Covid-19 pandemic has had a significant impact on the country’s
energy conditions, including renewable energy, not only in developing countries but also in
developed countries, globally. Referring to international stu.....
Opinion
Telemedicine: A Feasible Treatment for Burnout among Students Amidst the COVID-19 Pandemic and Thereafter
DOI: 10.31031/TTEH.2022.03.000561
Telemedicine became a game-changer in the health care system, especially during the current pandemic.
COVID-19 disrupted the lives of everyone, particularly the students who are deprived of the optimal
learning facilities and opportunities for socialization. These factors impacted their overall wellbeing
and considerably increased their stress and burnout. In this precarious situation, the study opines that
telemedicine is a feasible solution to address the emerging issue of burnout adequately by ensuring the
safety of students and professionals and the benefits of everyone. It can serve as an optimal response for
averting the risk of depression/addictions and maintaining their overall wellbeing. The techno-savvy
new generation can quickly adapt and greatly benefit from telemedicine.....
Research Article
Does the Fear of Needles Influence Jamaicans’ Willingness to be Vaccinated against COVID-19?
Introduction: As of November 21, 2021, the vaccination rate in the world is 55% (fully vaccinated,
43%) compared to 22% in Jamaica (17% fully vaccinated), 70% in the United States and Canada, 66%
in Latin America, Asia-Pacific (64%), Europe (62%), Middle East (45%), and 9.7% in Africa. A variable
proportion of each country’s population is delaying or avoiding vaccination, which may hamper the
success of vaccination programmes. The frequency of needle injections averaged from 2-11 per person
each year in 10 major regions globally in a study conducted by the World Health Organization [1-10].
Aim: To explore whether the fear of needles influences Jamaicans’ willingness to be vaccinated?”
Methods and materials: The study used an explanatory web-based cross-sectional design. A
sta.....
Mini Review
Importance of Palliative Care in Covid-19 Pandemic
Mohammad H, Chauhan A and Tamara H*
The novel corona virus (2019-nCoV or SARS-CoV-2) originated in Wuhan City of Hubei
Province of China in 2019 affecting millions of lives socially, economically and mentally.
According to worldometers, there are 235,955,154 total cases and 4,819,263 deaths reported
till 4/10/2021. Most of patients suffering from COVID-19 are either asymptomatic or have mild
symptoms, 5% require hospitalization and 1%-2%need Intensive Care Unit (ICU) admission
and ventilator support [1]. Highest mortality rate was found in older adults and patients
with chronic medical conditions and malignancies. As the virus is highly transmissible, many
people were devoid of meeting or even performing traditional rituals on the death of their
loved ones. During these hard times, palliative care workers had to push.....
Review Article
General Evaluation of Covid-19 Diagnosis Methods
Yakup Artik* and Nevra Pelin Cesur
DOI: 10.31031/CJMI.2022.05.000621
After the first case has appeared in China, the disease, COVID-19, continues to spread an omnipresent
threat to global health. The reliable, fast, and effective diagnosis methods are important to control the
pandemic. Today, the real-time Reverse Transcriptase (RT-PCR) test is the main diagnostic practice as
a gold standard method for accurate diagnosis of this disease. On the other side, serological assays are
easy to be implemented for disease screening. However, the actual limitations of these methods are
required skilled personnel and specialized infrastructure. Thus, in this direction, there is an urgency
to be implanted an appropriate method for the diagnosis of COVID-19 disease. Nowadays, the Reverse
Transcription Loop-Mediated Isothermal Amplification (RT-LAMP) technique is .....
Case Report
Use of Monoclonal Antibodies Drugs Etesevimab and Bamlanivimab for the Treatment of Coronavirus Infection (COVID-19) in Adults and Children
Halyna Bulak* and Andriy Zanevych
DOI: 10.31031/RPN.2022.06.000637
Coronavirus Disease (COVID-19) is an infectious disease caused by the SARS-CoV-2 virus, which is a contagious respiratory virus causing atypical pneumonia COVID-19 in adult and children with Severe Acute
Respiratory Syndrome (SARS). The SARS-CoV-2 genome also encodes four structural (S, E, M and N) and
up to six accessory (3a, 6, 7a, 7b, 8, and 9b) proteins. The spike protein (S) is further divided into 2 subunits, S1 and S2 that mediate host cell attachment and invasion. Anti-SARS-CoV-2 Monoclonal Antibodies
(mAbs) that target the spike protein have been shown to yield clinical benefits in treating SARS-CoV-2 infection. This article represents a clinical case of a 59-year-old man with Coronavirus Disease (COVID-19)
and intracerebral haemorrhage, who was treated with the use of monoclo.....
Review Article
Nanoparticles from Tulsi (Ocimum Sanctum) in Immune Enhancement against COVID-19 Situation
Dharita Desai and Thulasi G Pillai*
The world is witnessing the outbreak of COVID-19, a disease caused by a novel corona virus, SARSCoV-2. It has largely affected people throughout the world and has weakened their immune systems to
a great extent. To get rid of suffering and curing ailments and to enhance our immune system humans
have been using plants from prehistoric times. Nanoparticles in plants are referred to as building blocks
of nanotechnology. Plants produce stable nanoparticles and also the rate of synthesis is faster than
that of the microorganisms. Ocimum sanctum commonly known as tulsi is considered as “The Queen
of Herbs”. It has a significant role to play in traditional medicine. Several scientific studies have been
conducted to reveal the efficient use of the whole plant or its parts for the treatme.....
Commentary
Urban - Rural Demographic Movements Caused by The Covid 19 Pandemic
Knezevic Marija*, Mirka Kovacevica, Dragicevic Vedrana, Nikole Dobrovica and Racic Jelena
DOI: 10.31031/EAES.2022.09.000719
Covid 19. brought certain and visible social changes in terms of moving places of living and working from
urban to rural areas. These are sociologically encouraging indications of changes that will lead to relieving
cities, both with people and things, and on the other hand will revive rural areas that are, in our country,
great wealth and potential for healthier life and survival of future generations. These demographic shifts
should be encouraged by the state and all relevant departments, as these developments are of both regional
and global importance. They fit into the new pandemic (or post-pandemic) time - a time when health care
will be much more important and will be valorized through the search for a healthier environment for
housing, healthier food, sports and recreational .....
Review Article
Impact of COVID-19 Pandemic on Psychiatric Services
DOI: 10.31031/GGS.2022.07.000668
Background: The COVID-19 pandemic has led to unprecedented disruptions to the normal way of life
for people around the globe. Health services have been overburdened in both developed and developing countries. The impact of the ongoing pandemic on mental and physical health, jobs, and relationships
could be catastrophic, warranting collective action.
Aim: To evaluate the magnitude of COVID-19’ impacting on psychiatric services and health professionals,
as well as to gain useful insights into the potential health burden of similar pandemics and global disasters
in the future.
Materials and Methods: Published studies concerning mental health problems associated with the
COVID-19 outbreak and other global infections were considered and reviewed. A selective survey of the
literature, .....
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