Abstract

Introduction: Dermatoporosis is a classic clinical sign of collagen fragility of aging. This manuscript reviews the relationship to osteoporosis when you meet and greet the patient and look at their hands. This process is a common clinical finding and the clinician can see the implication when they first look at their patients’ hands.
Methods: We first demonstrated a patient who has these findings and we looked and took photographs of her hands and see the changes of Dermatoporosis. Clinicians see skin changes but are not aware of the implication of this change as we show in the manuscript. It is a direct clue to the patient having osteoporosis. Also seen is the collagen fragility causing bleeding after a blood draw. The research indicates this is a major issue throughout the body - collagen fragility
Results: At the time of the patient presentation, she had just had blood drawn by the certified phlebotomist who chose the back of her hands where the veins are prominent due to loss of tissues which is common in Dermatoporosis. Despite having expertise in drawing blood there was rapid bleeding in the dorsum of the left hand and also some bleeding in the dorsum of the right hand which we demonstrated in the photographs. In the follow up Photographs we show what the hand looks like after bleeding is resorbed. The literature Is reviewed regarding the clinical features of Dermatoporosis. Clinical research and investigative studies were reviewed which explained how it could occur and its implications for clinical care with some speculations as to how Dermatoporosis can and also should be treated.
Conclusion: This is common and seen right in front of one’s eyes but unrecognized clinical condition called Dermatoporosis. It indicates collagen fragility of aging and should alert the physician as to what steps should be taken in the care of the patient and also what risks patient have including osteoporosis, skin fragility and its importance of the being alerted to the association with osteoporosis and also its risk in the hospital because of the skin fragility especially in the care in the intensive care unit.

Keywords:Anti-aging gene sirtuin 1 (Sirt 1); Vitamin D; Dermatoporosis; Osteoporosis