Abstract

Background: Many recent reports suggest a link between blood groups and various manifestations of heart disease. This is a cross-sectional, prospective, analytical study aimed at determining the frequency of blood groups and secretor status among patients with cardiovascular diseases in Shendi locality from August to December 2021.
Methods: Seventy patients with different types of cardiovascular diseases who attended ELmek-nimer Hospital were enrolled. Informed consent was obtained from each patient before collecting blood samples and saliva. ABO and secretor status were determined using slide techniques and tube methods with specific antisera and indicator cells. Data were analyzed using the SPSS computer program.
Result: The results showed that the most common blood group among patients with cardiovascular disease was O, followed by A, then B, with AB being the least frequent. The majority (65.7%) of these patients were non-secretors. The most prevalent cardiovascular disease was more common in females compared to males, and it was most frequently diagnosed in elderly patients aged 51-85 years. The most common cardiovascular conditions included Dilated Cardiomyopathy and Coronary Artery Disease, followed by ischemic heart disease, while the least frequent was a permanent pacemaker.
Conclusion: The frequency of Ischemic Heart Disease (IHD) was higher in the A group, and the frequency of Dilated Cardiomyopathy (DCM) and Coronary Artery Disease (CAD) was higher in the O group. Finally, the results of the present study showed that there is no association of ABO blood group and secretor status with cardiovascular diseases.

Keywords:ABO; Cardiovascular diseases; Sudan; ABO blood group; Secretor status