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Abstract
Trends in Telemedicine & E-health
Brain Aging and Molecular Aspects of Age-Related Neurodegenerative Diseases
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Open or CloseTahira Farooqui* and Akhlaq A Farooqui
Department of Molecular and Cellular Biochemistry, The Ohio State University, USA
*Corresponding author:Tahira Farooqui, Department of Molecular and Cellular Biochemistry, The Ohio State University, Columbus, Ohio 43210, USA
Submission:October 08, 2024; November 14, 2024
ISSN: 2578-0271Volume5 Issue2
Abstract
Brain is a complex organ, which undergoes many morphological and biochemical changes during aging process. Brain aging not only alters cellular, vascular and structural characteristics, but also results in a cognitive dysfunction, and partial loss of memory. Age-related neurodegenerative diseases are caused by the onset of oxidative stress, neuroinflammation, axonal transport deficits, protein oligomerization and aggregation, calcium deregulation, mitochondrial dysfunction, genetic abnormalities and immune system problems.
Keywords:Neurodegenerative; Dysfunction; Demographic studies; Nutrients; Mild chronic inflammation
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