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Abstract

Significances of Bioengineering & Biosciences

The Roles of Ascorbic Acid in the Nervous System

  • Open or CloseSoleimanitadi S1, Saeediniya E2, Reaei P1, Dalirian A3, Dabbagh S1, Partoandaz H1, Sheikhi B4, Nasiri S5, Amini P6, Naderi M6 and Esmaeili H7*

    1Department of Medicine, Iran University of Medical Science, Iran

    2School of Medicine International Campus Iran University of Medical Science, Iran

    3Medical Student, Department of Medicine, Iran University of Medical Science, Tehran, Iran

    3School of Medicine, Iran University of Medical Sciences, Iran

    3Bachelor of Science in Nursing, Islamic Azad University Semnan Branch, Iran

    3Medical Student, Tehran Medical Sciences, Islamic Azad University, Iran

    3Young Researcher and Elite Club, Medical Department, Tehran Medical Sciences, Islamic Azad University, Iran

    *Corresponding author: Hossein Esmaeili, Young Researchers and Elite Club, Medical Department, Tehran Medical Sciences, Islamic Azad University, Iran

Submission: July 09, 2021;Published: August 06, 2021

DOI: 10.31031/SBB.2021.05.000606

ISSN 2637-8078
Volume 5 Issue 2

Abstract

However different aspect of vitamin c’s affect is not cleared till now, but it is proved that Vitamin C plays several key roles in our body specially during early postnatal period and in natural developing brain specially hippocampus and spatial memory neurons . It must be noticed that it’s deficiency also effects memory involved neurons in early life. Some other researches [1] show that Vitamin C regulates transcription of many vital proteins such as collagen notably in sciatic nerves which prevents some sensorimotor disorders.

Keywords: Vitamin C; Nervous system; Ascorbic acid

Abbreviations: DHA: Dehydroascorbic Acid; AA: Ascorbic Acid; SNS: Sympathetic Nervous System; PTZ: Pentylenetetrazol; CA3: Cornu Ammonis 3; BH4: Tetrahydrobiopterin; BH2: Dihydrobiopterin; CA1: Cornu Ammonis 1; A3R: A3 Receptors; ROS: Reactive Oxygen Species; SVCT: Sodium±Vitamin C Co-Transporters; AD: Alzheimer Disease; VDR: Vitamin D Receptor

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