Crimson Publishers Publish With Us Reprints e-Books Video articles

Abstract

Research in Pediatrics & Neonatology

Physiology Principles Underlying Goal Directed Therapies in Children

  • Open or CloseKumba C*

    Department of Pediatric Anesthesia and Critical Care, Necker Enfants Malades University Hospital, Assistance Publique Hôpitaux de Paris, APHP, University of Paris, Paris, France
    Ecole Doctorale 563 Médicament-Toxicologie-Chimie-Imageries (MTCI), Université de Paris, Paris, France

    *Corresponding author: Kumba C, Department of Pediatric Anesthesia and Critical Care, Necker Enfants Malades University Hospital, Assistance Publique Hôpitaux de Paris, APHP, University of Paris, Paris, France Ecole Doctorale 563 Médicament- Toxicologie-Chimie-Imageries (MTCI), Université de Paris, Paris, France

Submission: May 15, 2020; Published: June 04, 2020

ISSN : 2576-9200
Volume4 Issue4

Abstract

Background: Goal directed therapies (GDT) include goal directed fluid and hemodynamic therapy (GDFHT), transfusion goal directed protocols (TGDP) and enhanced recovery after surgery (ERAS). These GDT share common aims which are to optimize tissular oxygen delivery (DO2), oxygen consumption (VO2) and extraction ratio (O2ER).

Objectives: This editorial on the Thesis Project entitled ´Do goal directed therapies improve postoperative outcome in children’ highlights the physiology and rationale of GDT.

Methods: Editorial on the rationale of the Thesis Project in GDT in children.

Result: GDFHT, TGDP and ERAS have the same aim which is the optimization of tissular DO2, VO2 and O2ER to avoid and prevent organ dysfunction.

Conclusion: Understanding the physiology of GDT is important for optimal patients management.

Keywords: Goal directed fluid and hemodynamic therapy; Transfusion goal directed protocols; Enhanced recovery after surgery; Postoperative outcomes, Children; Oxygen delivery; Oxygen consumption; Oxygen extraction ratio; Tissular perfusion pressure

Get access to the full text of this article

About Crimson

We at Crimson Publishing are a group of people with a combined passion for science and research, who wants to bring to the world a unified platform where all scientific know-how is available read more...

Leave a comment

Contact Info

  • Crimson Publishers, LLC
  • 555 Madison Avenue, 5th floor
  •     New York, NY 10022, USA
  • +1 (929) 600-8049
  • +1 (929) 447-1137
  • info@crimsonpublishers.com
  • www.crimsonpublishers.com