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Abstract

Research in Medical & Engineering Sciences

Potential Value of Anti-inflammatory in the Prevention and Treatment of Deep Vein Thrombosis

  • Open or CloseLi Li Sun, Ming Zhang* and Xiao Qiang Li*

    Department of Vascular Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu, China

    *Corresponding author: Xiao Qiang Li and Ming Zhang, MD, PhD, Department of Vascular Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, #321 Zhongshan Road, Nanjing, 210008, Jiangsu, China

Submission: November 22, 2022;Published: November 29, 2022

DOI: 10.31031/RMES.2022.10.000728

ISSN: 2576-8816
Volume10 Issue 1

Abstract

The incidence of deep vein thrombosis (DVT) has been increasing in recent years. In addition to endothelial injury, blood stasis and hypercoagulability, thromb-inflammation describes the complex interplay between inflammation and coagulation that plays a critical role in the pathophysiology of DVT. Leukocytes, endothelial cells and platelets interact with each other, which promote inflammation and play a key role in DVT formation and development. Here, we review the relationship between inflammation and DVT, providing potential value for the development of anti-inflammatory drugs in the prevention and treatment of DVT.

Keywords:Thrombo-inflammation; Coagulation; Deep vein thrombosis; Anti-inflammatory

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