Abstract

This study probed into the potential application of Taiwan’s endemic plant, Hinoki, and the by-product distilled from Hinoki, Hinoki hydroso, to inhibiting Candida albicans. Candida albicans is a polymorphic fungus. It has become a common pathogenic bacteria causing nosocomial infections. Hinoki hydroso is a plant fungicide. It is a volatile substance released from plants to protect them against pathogens and insects. It has known insecticidal, antimicrobial, and antifungal properties.

In the experiment, the Hinoki hydroso was diluted in different concentrations. Partial inhibition of Candida albicans was observed at a concentration of 25%, and a greater inhibition was observed at 50%. Its growth was completely inhibited at a concentration of 75%. However, they grew at 12.5%, 25%, 50%, and 62.5% concentrations. No growth was observed, only at 75% and 100% concentration. According to the experimental results, the Minimum Inhibitory Concentration of Taiwan’s endemic Hinoki hydroso extracted in this study for Candida albicans is 75%. The minimum bactericidal concentration of 25% partially inhibits the growth of Candida albicans.

This study provided important insights into Taiwan’s endemic plants’ conservation and sustainable utilization. It opened a new direction for the potential application of Hinoki hydroso for antifungal treatment.

Keywords:Candida albicans; Hydrolat; Minimum inhibitory concentration; Minimum bactericidal concentration