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Abstract
Open Access Research in Anatomy
Augmenter of Liver Regeneration in ROSinduced Pathophysiological Conditions
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Sudhir Kumar* and Richa Rani
Department of Pediatrics, Cincinnati Children’s Hospital Medical Center, USA
*Corresponding author: Sudhir Kumar, Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA
Submission: April 16, 2018; Published: April 20, 2018
ISSN: 2577-1922 Volume2 Issue1
Abstract
Augmenter of liver regeneration (ALR), also described as hepatopoietin (HPO) and hepatic stimulator substance or hepatic regenerative stimulation substance (HSS), is representative member of ERV protein family with flavin-linked sulfhydryl oxidase activity, that facilitate the formation of disulfide bonds in reduced protein substrates [1]. Growing numbers of evidence demonstrate the involvement of ALR in maintaining cellular redox communication under various pathophysiological conditions [2-7].
Keywords: Antioxidant; Augmenter of liver regeneration; Liver injury; Oxidative stress; Reactive oxygen species:
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