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Abstract
Novel Research in Sciences
One-Pot Multicomponent Synthesis of Novel 2-Imino-1,3-Thiazolidin-4-One
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Open or CloseAbdelhamid AA*, Salah HA, Amany SE and Amer AA
Department of Chemistry, Egypt
*Corresponding author:Abdelhamid AA, Department of Chemistry, Egypt
Submission: October 21, 2019;Published: November 12, 2019
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Abstract
A novel series of 2-imino-1,3-thiazolidin-4-one were synthesized via simple efficient method through one-pot three-component reaction of phenyl isothiocyanate, primary amines and dimethyl acetylene dicarboxylate. The same products were synthesized via conventional route by reaction of the corresponding thiourea derivatives with dimethyl acetylene dicarboxylate
Keywords: 1,3-thiazolidin-4-one; Dimethyl acetylene dicarboxylate (DMAD); One-pot multicomponent reaction; Thiourea derivatives; Phenyl isothiocyanate
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