Abstract

The role genes play in cancer progression and cancer subtypes has gained interest in research over the years. Numerous studies have focused on the potential proliferation of oncogenes and their transformation from proto-oncogenes. Through various research, these components have led to unique cases of cancer. Oncogenic occurrences are being studied to limit their influences on future generations, as their relation to the increasing rates of specific cancer types has not gone unnoticed. The focus of this will be on the effects of oncogenes and proto-oncogenes in breast cancer development. The specific oncogenes discussed in this paper are sectioned into three groups based on the effects of their mutations, and these three groups are tyrosine-kinase activity, transcription factors, and GTPase activity. Moreover, the study of these oncogenes can reveal a novel understanding of breast cancer, which can then be applied to develop treatments.

Keywords: Oncogene;Proto-oncogene;Tyrosine-kinase activity;Transcription factors; GTPase activity