Abstract

The ease of use, simple and direct treatment plans, avoidance of the first-pass effect, avoidance of high maximum plasma concentrations with rapid changes in drug levels, and lack of invasive procedures associated with intravenous treatment are all advantages that transdermal patches can provide to patients over oral formulations. The mode of drug delivery can be a significant factor in optimising drug therapy as it can affect treatment compliance and outcomes. The development of ideal drug formulations is crucial for treating chronic illnesses or ailments that affect the elderly and for which treatment compliance is known to be low. The characteristics and advantages of transdermal formulations for the treatment of neurological disorders in elderly persons are discussed in this review.

Keywords: Drug; Formulations; Neurological; Disorders; Transdermal patches