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Abstract

Innovation in Tissue Engineering & Regenerative Medicine

Accelerated Regeneration of Human Skin using Acellular Fish Skin Grafts: A Comprehensive Review

  • Open or CloseSandipan Nag¹, Soumili Ghosh¹ and Pranab Roy²*

    1Department of Biotechnology, Haldia Institute of Technology, India

    2Department of Molecular Biology, Institute of Child Health, India

    *Corresponding author:Pranab Roy, Department of Biotechnology, Haldia Institute of Technology, Haldia, 721657, India

Submission: July 23, 2024; Published: September 11, 2024

DOI: 10.31031/ITERM.2023.02.000528

ISSN: 2578-0336
Volume2 Issue1

Abstract

The quest for effective wound healing strategies has led to the exploration of novel biomaterials, with acellular fish skin grafts emerging as a promising solution for accelerating the regeneration of human skin. This comprehensive review provides an in-depth analysis of the scientific literature surrounding the application of acellular fish skin grafts in wound care and tissue regeneration. Drawing upon evidence from experimental studies, clinical trials, and mechanistic investigations, the review elucidates the structural, biochemical, and immunomodulatory properties of fish skin that contribute to its efficacy as a biomimetic scaffold for skin regeneration. Through a synthesis of key findings, the review highlights the diverse applications of acellular fish skin grafts in promoting accelerated wound healing, reducing scar formation, and enhancing tissue regeneration across various acute and chronic wound conditions. Furthermore, the review discusses ongoing research efforts aimed at optimizing graft design, manufacturing processes, and clinical delivery methods to maximize therapeutic outcomes and ensure widespread accessibility of fish skin-derived products. By offering insights into the potential of acellular fish skin grafts to revolutionize wound care and tissue engineering, this review underscores their significance as a transformative approach in the field of regenerative medicine.

Keywords:Acellular fish skin grafts; Chronic wounds; Xenograft; Tissue regeneration; Wound healing

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