Clinic of Cardiovascular Diseases named after Most Holy John Tobolsky, Moscow, Russia
*Corresponding author:Ivan V. Maksimovich, Clinic of Cardiovascular Diseases named after Most Holy John Tobolsky, Moscow, Russia
Submission: September 23, 2024;Published: October 01, 2024
ISSN 2578-0093Volume 9 Issue 2
Aim: The research is devoted to the clinical application of transcatheter intracerebral Laser Photo Bio Modulation Therapy (PBMT) for angiogenesis stimulation, cerebral collateral blood supply restoration, neurogenesis stimulation, cerebral tissues regeneration in ischemic stroke treatment.
Methods: 953 patients aged 30-80 (average age 74.6) with ischemic stroke were examined. There were 696 men (73.03%) 257 women (26.97%).
Test group: 610 (64.01%) patients underwent transcatheter intracerebral laser PBMT, of whom 354 (58.04%) had small focal stroke, 189 (30.98%) had medium focal stroke and 67 (10.98%) had macrofocal stroke.
Control group: 343 (35.99%) patients underwent conservative treatment, of whom 256 (74.64%) had small focal stroke, 43 (12.54%) had medium focal stroke and 44 (12.82%) had macrofocal stroke.
Results
Test group: Angiogenesis stimulation, cerebral collateral blood supply restoration, neurogenesis stimulation and cerebral regenerative processes were achieved in all 610 cases regardless of the patients’ age. Good clinical result was obtained in 313 (88.42%) patients with small focal strokes, in 114 (60.32%) patients with medium focal strokes, in 14 (20.90%) patients with macrofocal strokes. Satisfactory clinical result was obtained in 36 (10.17%) patients with small focal strokes, in 48 (25.39%) patients with medium focal strokes, in 27 (40.30%) patients with macrofocal strokes.Keywords:Ischemic stroke; Therapeutic targets; Transcatheter intracerebral laser photobiomodulation therapy; PBMT; Angiogenesis; Neurogenesis; Regeneration