1 Department of Mathematics and Statistics, University of Lahore, Pakistan
2 Department of Allied Health Sciences (DPT), University of Lahore, Pakistan
*Corresponding author: Muhammad Farman, Department of Mathematics and Statistics, Pakistan
Submission: December 12, 2018; Published: January 09, 2019
ISSN: 2578-0395Volume2 Issue4
In this manuscript, Immunotherapy with Bacillus Calmette Guerin (BCG) vaccine is used for the treatment of superficial bladder cancer. Considered the cancer model regarding tumor- immune interactions in the bladder as a result of BCG therapy having four variables, B, E, Ti and Tu represents the vaccine for the immune system, effector cells, the total population of affected and unaffected cells respectively. Controllability and observability are treated for logistic model according to dimensionless estimate parameters values. Also numerical simulation are carried out to show the actual behavior of the system.