Abstract

Intelligence antimicrobial strategy with bacterial release function can solve the problem of accumulation of dead bacteria and thus biofouling. Many stimulus-responsive intelligence antimicrobial surfaces have been developed based on this strategy, such as responding to stimuli such as pH, temperature, salt solution and light. Sugar-responsive antimicrobial strategies have been developed to achieve gentler intelligence antimicrobial surfaces, mainly based on Phenylboronic Acid (PBA) and boronate ester bonds between various diol containing biomolecules trigger the bactericidal activity of the surface, which is then treated with a sugar solution to release bacterial debris. In addition, a multi-functional and multiresponsive intelligent antibacterial surface can be prepared by combining sugar stimulation with other stimuli. It provides the foundation for realizing the long-term efficient and renewable antibacterial target.

Keywords:Biofilms; Adherent bacteria; Antifouling; Bactericidal function; Antimicrobial