The Author ensures that the research has been conducted responsibly and ethically with adherence to all relevant regulations. read more..
1Clinic of Poultry Diseases, Yazd province, Iran
2Department of Pathology, University of Tabriz,Iran
*Corresponding author: MonireKhordadmehr,Department of Pathology, Faculty of Veterinary Medicine,University of Tabriz, Tabriz, Iran
Submission: June 01, 2018; Published: July 02, 2018
ISSN: 2576-9162Volume4 Issue1
Marekʼs disease, a Herpesvirus-induced lymphoproliferative disease, is known to affect chickens and other domesticated and wild birds.One of the five green peafowls (Pavomuticus) in the owner’s collection had already died. The affected bird showed non-specific clinical signs such as depression, weight loss and anorexia. At necropsy, the liver and spleen were observed diffuse enlargement accompanied by several times the normal size with white to gray in color and firm, and the cut surface was smooth. Grossly, the other visceral organs were normal. Histopathological and immunohistochemical examination were done for the affected tissues. Diffuse infiltration of the liver and spleen caused loss of normal architecture.Tumor cells are characterized by large, pleomorphic nuclei with prominent nucleoli. According to immunohistochemical findings, the majority of transformed T cells expressed CD4-/ CD8+.In addition, the immunohistochemistry for CD30 were positive. In PCR, MDV was detected by specific primers. To our knowledge, this is the first report of Marek’s disease in peafowls (Pavomuticus) which were infected naturally and had thought is refractory to this infection.
Keywords: Marekʼs disease;Herpesvirus;Green peafowl; Lymphoma; Tumor cells
Abbreviations: IHC: ImmunoHistoChemical; ICTV: International Committee on Taxonomy of Viruses;MDV: Marek’s Disease Viruses; NK: Natural killer
Ph.D in Agriculture from Faculty of Agriculture, Tohoku University
Research Professor, PhD, Holistic Research Institute
Professor, Chief Doctor, Director of Department of Pediatric Surgery, Associate Director of Department of Surgery, Doctoral Supervisor Tongji hospital, Tongji medical college, Huazhong University of Science and Technology
Senior Research Engineer and Professor, Center for Refining and Petrochemicals, Research Institute, King Fahd University of Petroleum and Minerals (KFUPM), Dhahran, Saudi Arabia
Fellow of International Agency for Standards and Ratings (IASR), Edith Cowan University, Sarich Neuroscience Research Institute
Chancellor Emeritus / Professor Emeritus of Chemistry and Physics, University of Missouri–St. Louis
Ph.D in Science from the Federal University of Alagoas, UFAL, Brazil
Assistant Professor in College of Architecture, Art and Design
Interim Dean, College of Education and Health Sciences, Director of Biomechanics Laboratory, Sport Science Innovation Program, Bridgewater State University
Professor of numerous training courses in Family Medicine
Assistant Professor, Department of Electronics and Computer Science
Emeritus Professor of Physics, Kadir Has University, Turkey
Wenzhou Medical University, China
Fooyin University, Taiwan
Saglik Bilimleri University, Turkey
Vincent Pol University, Poland
National Defence University of Malaysia, Malaysia
Dogus University, Turkey
Hope College, USA
Russian Academy of Sciences, Russia
Southern Cross University, Australia
Umm Al-Qura University, Saudi Arabia
City University of New York, USA
Khalifa University of Science & Technology, United Arab Emirates
Hebei Normal University, China
Alexandria University, Egypt
Indian Institute of Technology Kharagpur, India
Council for Agriculture Research and Analysis of Agri Economy (CREA), Italy
King Fahd University of Petroleum and Minerals, Saudi Arabia
King Abdulaziz University, Saudi Arabia
University of Oregon, USA
University of Edinburgh, Scotland
University of Tennessee, USA
Central University of Venezuela, Venezuela
Islamic Azad University Central Tehran Branch, Iran
Tourin University, Italy
Teaching & Public Speaking, Spain
Paeditric Hospital "Giovanni XXIII", Italy
University of Nicosia, Cyprus
Universidad Miguel Hernández de Elche, Spain
Oral Roberts University, USA
Beijing Normal University, China
Howard University, USA
Edith Cowan University, Australia
Dubai Health Authority, UAE
University of Minnesota, USA
Indian Institute of Technology Kharagpur, India
Serhal Hospital, Lebanon
University of Malta, Malta
National Center for Global Health and Medicine, Japan
Molloy College, USA
Federal University of Piauí, Brazil
Krankenhaus Nordwest Hospital, Germany
Laval University, Canada
Cinvestav-Unidad Saltillo, Mexico
UPMC Hamot Neuroscience Institute, USA
Ramon Llull University, Spain
White Bear Associates, LLC, USA
Lehigh University, USA
California Southern University, USA
Institute of Solid State Physics of RAS, Russia
University of Buenos Aires, Argentina
Mansoura University, Egypt
King Saud University, Saudi Arabia
University of Coimbra, Portugal