Abstract

Background: Measles remains one of the leading causes of death among children around the world. Encephalitis is the most serious complication of measles virus infection.

Case presentation: We report two measles-induced encephalitis who was admitted to to Kyiv City Pediatric Infectious Clinical Hospital. One patient had postinfectious variant of measles encephalitis that occurred 6 days after primary measles infection onset. Disease had benign course with substantial improvement during hospital stay. Another patient presented with subacute sclerosing panencephalitis. Neurological symptoms started 10 years after measles infection. Disease characterized by progredient course and unfavorable outcome.

Conclusion: Measles encephalitis is rare but serious and often deadliest complication. It should be considered in differential diagnostic of CNS infection among pediatric patients.

Keywords: Measles, Encephalitis, Children