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Dr. Adel Abdulrahman Alkhudiri*
King Saud University, Saudi Arabia
*Corresponding author:Dr. Adel Abdulrahman Alkhudiri, King Saud University, Riyadh, Saudi Arabia
Submission: November 19, 2025;Published: December 09, 2025
ISSN: 2689-2707 Volume 6 Issue 2
The integration of Artificial Intelligence (AI) technologies into healthcare represents a qualitative transformation in medical practice, offering unprecedented capabilities in diagnosis, treatment, and patient management. However, the growing reliance on these systems raises potential risks concerning patient safety, privacy protection, and clinical decision-making mechanisms, in addition to ethical challenges associated with healthcare delivery. This research article aims to systematically analyze these risks and propose practical strategies to mitigate them, thereby achieving the desired balance between technological integration and human oversight. The study seeks to ensure the safe and responsible use of AI in the healthcare sector by offering practical recommendations and an applied framework for AI applications in healthcare.
Keywords:Artificial intelligence; Risks, Safety; Healthcare; Ethics
Recent years have witnessed rapid advancements in AI technologies, directly impacting the healthcare sector. These technologies have become pivotal tools in enhancing diagnostic accuracy, supporting clinical decisions, and managing patient data with unprecedented efficiency. This transformation has reshaped medical practices, raising expectations for higher levels of quality, speed, and precision in healthcare delivery. With the proliferation of smart health applications and wearable devices, individuals increasingly rely on AI for medical consultations and instant responses to their symptoms. Nevertheless, this growing dependence on AI systems introduces a set of challenges and risks that cannot be overlooked, including medical safety concerns, privacy protection, fairness in diagnosis and treatment, and ethical and legal dimensions of technology use [1]. The central question thus emerges: how can healthcare systems balance the immense potential of AI with the indispensable role of human expertise in ensuring patient safety and quality of care? This article seeks to analyze the potential risks of complete reliance on AI in healthcare, review relevant regulatory and ethical frameworks, and propose practical and technical strategies to mitigate these risks. Ultimately, the study contributes to shaping a balanced vision that integrates technological innovation with human oversight, ensuring the safe and responsible use of AI in service of humanity [2].
The significance of this research lies in its focus on human health and the urgent need to
raise awareness of the risks associated with complete reliance on AI platforms and applications
for self-treatment or medication intake without professional consultation [3]. Awareness
represents the most effective tool for protecting individuals and ensuring the responsible
use of these technologies. Despite the substantial benefits of AI in improving diagnostics and
supporting medical decisions, absolute dependence on it entails
multiple risks across three main dimensions:
a. Medical Dimension: Potential diagnostic errors and insufficient
human monitoring.
b. Human Dimension: The diminishing role of physicians
weakened patient-provider relationships, and reduced
reliance on human expertise in decision-making.
c. Legal and Ethical Dimension: Conflicts between AI-driven
decisions and principles of justice, privacy protection, and
legal accountability.
Accordingly, this research highlights the risks of complete reliance on AI and underscores the necessity of striking a balance between harnessing its capabilities and preserving the central role of human expertise in safeguarding patient safety and healthcare quality [4].
Artificial Intelligence (AI)
A set of systems and algorithms capable of simulating human cognitive abilities, analyzing large datasets, and producing accurate results rapidly.
AI in medicine
Systems capable of analyzing medical data, identifying patterns, and making semi-autonomous decisions, such as interpreting radiological images, analyzing laboratory samples, proposing treatment plans, predicting chronic diseases, offering therapeutic recommendations, and enabling self-monitoring of health conditions through applications [5].
Individual reliance on AI in medicine
Refers to the complete or near-complete dependence of individuals on AI recommendations for managing health symptoms or making medical decisions without consulting a specialist [6]. This growing reliance raises questions about the safety of such practices, particularly in cases of potential errors.
Examples include:
a. Using applications to diagnose symptoms.
b. Following treatment plans suggested by AI systems without
physician review.
c. Relying on health chatbots for medical advice.
d. Using smartwatches to determine health indicators and make
treatment decisions.
e. Misdiagnosis due to self-reliance on AI applications.
f. Unsafe treatment management, such as adjusting medication
dosages based on automated recommendations without
medical supervision.
g. Delayed medical care due to excessive trust in AI selfassessments.
Diagnostic errors
AI systems may produce inaccurate diagnoses due to limited
training data or algorithmic biases. Errors may arise from:
a. Inaccurate or biased training datasets, such as
underrepresentation of certain populations.
b. Incomplete understanding of the patient’s full health context.
c. Neglect of subtle human factors beyond algorithmic inference.
d. Inappropriate treatment recommendations based on
incomplete patient information.
e. Failure to recognize critical cases requiring immediate human
intervention.
f. System vulnerabilities and single points of failure [7].
g. Consequences include delayed treatment, inappropriate
interventions, and worsening health conditions.
Excessive dependence and loss of independent judgment
Complete reliance on AI diminishes individuals’ ability to independently assess their health, reducing awareness of symptoms and weakening their role in medical decision-making [8].
Privacy and data protection risks
a. AI applications collect vast amounts of sensitive health data.
Risks include:
b. Data analysis without explicit consent.
c. Patients’ lack of awareness of how their data is used in AI
algorithms.
d. Re-identification of individuals from anonymized datasets.
e. Commercial exploitation of health data for non-medical
purposes without informed consent.
f. Data breaches and leaks exposing sensitive health information.
Algorithmic risks in healthcare AI
AI systems may reflect biases inherent in training data, leading
to:
a. Inaccurate decisions for underrepresented populations.
b. Variations in healthcare quality, with some patients
receiving inferior services.
c. Unfair or biased diagnoses conflicting with medical
justice [9].
d. Hidden influence on patient choices through imperceptible
manipulation of recommendations.
Ambiguity in legal and ethical responsibility
The absence of clear legal frameworks exacerbates risks of patient rights violations in cases of medical error. Questions arise regarding accountability-whether it lies with the application developer, the producing company, or the individual relying on AI.
Threats to the patient-physician relationship
Complete reliance on AI may reduce human interaction, leading
to:
a. Declining trust.
b. Weak continuity of care.
c. Absence of psychological support for patients.
d. Exclusion of elderly or less-educated individuals from quality
care.
Decision-making risks
a. Bias and uncritical acceptance of AI recommendations.
b. Decline in clinical skills and expertise among healthcare
providers.
c. Gaps in understanding and inability of AI to account for unique
patient circumstances and preferences.
d. Overreliance on pattern recognition, overlooking rare cases
not represented in training data.
Diagnostic AI systems
Several studies have shown that AI-based diagnostic tools may exhibit reduced performance when dealing with underrepresented populations in training datasets, leading to inaccurate or biased outcomes [10].
Excessive reliance on automated recommendations
Documented cases of misdiagnosis have resulted from complete reliance on AI recommendations without human review, highlighting the danger of excluding clinical expertise from decision-making processes.
Patient-oriented AI applications
Some health applications provide therapeutic or preventive advice that may be unsafe, particularly in the absence of clear disclaimers. This can lead patients to delay necessary medical care or make unsafe decisions [11].
Impact of unregulated applications on patient behaviour
A study revealed that approximately 40% of users make treatment decisions based on unregulated applications, underscoring the danger of widespread use of such tools without oversight or official approval [12].
Trust of young physicians in AI systems
Another study found that 30% of young physicians trust AI recommendations more than their own expertise or that of their colleagues, raising concerns about declining reliance on traditional clinical judgment [13].
This research article is based on a systematic review of scientific literature, peer-reviewed articles, and relevant studies, in addition to examining regulatory documents and applied case studies. The focus is on a comprehensive analysis of key domains associated with risks in healthcare AI use, including safety, privacy, clinical decision-making, and ethical dimensions [14]. The methodology aims to construct an integrated knowledge framework that bridges theoretical evidence with practical experiences, enabling the evaluation of existing challenges and the proposal of regulatory and technical solutions to promote safe and responsible use of these technologies [15].
Strengthening governance and regulation
a. Establish clear regulatory frameworks defining the
responsibilities of different stakeholders in AI use.
b. Adopt auditing and periodic review protocols to ensure
compliance with quality and safety standards [16-20].
Human oversight and accountability
a. Guarantee human supervision of AI-assisted medical decisions.
b. Define clear legal and ethical accountability mechanisms in
cases of errors or deviations.
Post-market surveillance
a. Create systems to monitor the real-world performance of AI
systems after clinical integration.
b. Develop mechanisms for early detection of technical issues or
potential medical errors.
Educational and training initiatives
a. Train healthcare providers on the limitations and capabilities
of AI.
b. Educate patients on the appropriate use of these technologies
to enhance trust and awareness.
c. Develop curricula that preserve the independence of human
clinical decision-making.
Integration of AI and human expertise
a. Design AI systems as decision-support tools rather than
replacements for physicians.
b. Strengthen partnerships between AI and healthcare
practitioners to achieve maximum efficiency and safety [21-
26].
Strategies for risk mitigation in healthcare AI
a. Develop a comprehensive regulatory framework aligned with
international standards.
b. Establish healthcare-specific legislation defining boundaries
for AI use in diagnosis and treatment.
c. Mandate rigorous verification and approval processes before
adoption of AI systems.
d. Enforce post-market monitoring requirements to detect side
effects or technical issues.
e. Design AI tools that support, rather than replace, human
decision-making.
f. Implement continuous monitoring mechanisms to detect
errors or system failures.
g. Enhance digital literacy among healthcare professionals
through specialized training programs [27].
WHO guidelines
The World Health Organization has established a reference
framework for integrating AI into healthcare, emphasizing quality
monitoring, transparency, and patient data protection. This
includes:
a. Regulating AI use in line with global health standards.
b. Establishing clear accountability mechanisms for errors or
deviations.
c. Developing formal accreditation and periodic review systems
to ensure compliance with safety and quality standards [28].
Ethical principles
International guidelines stress adherence to core principles in
healthcare AI use, including:
a. Transparency in decision-making processes.
b. Fairness and non-discrimination to ensure equal care for all
populations.
c. Protection of privacy and safeguarding sensitive medical data
[29].
d. Ensuring patient safety and preventing harm from reliance on
AI systems.
Legal regulations
There is a pressing need for clear legislation defining
responsibility in AI-assisted medical decisions to protect patients
and build trust. While legal frameworks in Arab countries remain in
early stages, growing interest is evident in developing regulations
that include:
a. Protection of medical data and confidentiality.
b. Safeguarding patient rights and strengthening trust in modern
technologies [30].
c. Providing safety guarantees when integrating AI into clinical
practice.
a. Explainable AI (XAI): Develop systems capable of clarifying
decision-making processes, enhancing transparency, and
enabling healthcare providers to understand the basis of
diagnoses or treatment recommendations.
b. Robust Testing Across Diverse Populations: Subject AI systems
to comprehensive trials covering varied demographic groups
to ensure accuracy, fairness, and quality of care [31].
c. Continuous Performance Monitoring: Establish technical
mechanisms for ongoing evaluation of AI systems in clinical
practice, enabling early detection of errors and continuous
improvement.
a. Training Healthcare Providers on AI Limitations: Specialized
programs to raise awareness among physicians and
practitioners about the boundaries of AI capabilities, ensuring
safe and informed use.
b. Patient Education on Responsible AI Use: Awareness
campaigns to help patients understand the role of AI in
diagnosis and treatment, emphasizing the importance of
consulting physicians.
c. Preserving Clinical Decision-Making Skills: Curricula designed
to strengthen critical thinking and independent medical
judgment, ensuring AI remains a supportive tool rather than a
substitute for human expertise.
a. Human Oversight Requirements: Ensure direct human
supervision of AI-assisted decisions, with final responsibility
resting on healthcare practitioners.
b. Clear Accountability Structures: Define legal and ethical
mechanisms for responsibility in cases of AI-related errors
[32].
c. Regular Auditing Protocols: Enforce periodic reviews and
comprehensive audits of AI systems to verify compliance with
safety and quality standards.
a. AI should be used as a supportive tool, not a complete
substitute.
b. Strengthen integration between AI and human expertise under
physician supervision.
c. Raise public awareness of AI limitations and emphasize the
importance of medical consultation.
d. Develop clear legal frameworks regulating AI use in medicine
and defining responsibilities.
e. Ensure robust data governance and user privacy protection
[33].
f. Adopt strict cybersecurity standards for health data protection.
g. Verify the quality of health applications through accredited
regulatory bodies.
h. Support scientific research to improve algorithmic accuracy
and reduce bias.
i. Develop explainable AI systems whose decisions can be easily
interpreted and reviewed [34].
Artificial intelligence represents a fundamental transformation in healthcare [35]. However, complete reliance on it by individuals entails medical, legal, and ethical risks that cannot be ignored. This research emphasizes the necessity of balancing AI use with the central role of human expertise to ensure patient safety and healthcare quality. The optimal future lies not in replacing physicians with AI, but in establishing a balanced partnership between them to achieve the highest levels of efficiency and safety.
© 2025 Dr. Adel Abdulrahman Alkhudiri. This is an open access article distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and build upon your work non-commercially.
a Creative Commons Attribution 4.0 International License. Based on a work at www.crimsonpublishers.com.
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