Abstract

Arnica Montana (AM), a well-known medicinal herb, has been widely utilized for its anti-inflammatory and analgesic properties. Recent advancements in transdermal drug delivery have led to the development of hydrogel patches containing AM extract, offering advantages such as enhanced adhesion, sustained release, and improved bioavailability. This review evaluates the pharmacological mechanisms, comparative efficacy, clinical applications and safety of AM hydrogel patches (AHPs; Arnipatch™, Laboflex Inc.). Experimental studies and clinical trials demonstrate AHPs’ superior performance over conventional topical gels in reducing inflammation and pain. Despite promising results, further research is necessary to optimize formulations and confirm long-term safety and efficacy.

Keywords: Arnica patch; Edema; Anti-inflammatory; Inhibitory effects; Pain relief