Abstract

In the course of a cohort prospective comparative study (n=41; of them 58.54%; n=24 - women and 41.46%; n=17 - men; mean age - 42.71±6.42 years) of the effectiveness of influence on acute pain in the structure of the muscular-tonic syndrome of celecoxib without and with the addition of a combined vitamin complex of group “B” (B1, B6, B12) in comparison with meloxicam, in patients with acute nonspecific pain syndrome in the lower back, it was found that in the absence of comorbid pathology , both drugs are equally effective and safe, and the duration of therapy should be at least 10-11 days. The combination of celecoxib with a combined vitamin complex (group “B” - Neuromultivit) gives the best result (p<0.05). Miscellaneous Pain Rating (MPR) according to MPQ (characterization of the feelings that cause pain, the impact of pain on the psyche of patients) is of great importance for the degree of pain perception in OPS in the structure of the muscular-tonic syndrome with HADS <7 p., i.e., accentuation of the patient’s personality.

Keywords:Acute pain syndrome; Celecoxib; Meloxicam; B Vitamins