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Abstract

Perceptions in Reproductive Medicine

Recurrent Pregnancy Loss in Thrombophilia and Role of Anticoagulation Therapy: A Systematic Review

  • open or closeMihaela Andreescu1,2*

    1Department of Clinical Sciences, Hematology, Faculty of Medicine, Titu Maiorescu University of Bucharest, Romania

    2Department of Hematology, Colentina Clinical Hospital, Romania

    *Corresponding author:Mihaela Andreescu, Department of Clinical Sciences, Hematology, Faculty of Medicine, Titu Maiorescu University of Bucharest, Romania

Submission: March 10, 2023Published: March 27, 2023

Volume5 Issue4
March , 2023

Abstract

Thrombophilia also called a prothrombic state or hypercoagulability is a condition in which there is an increased tendency of the body to form clots. RPL is the most serious problem in both early and late gestation. I performed a review to establish the correlation of thrombophilia with recurrent pregnancy loss. The aim of this review was to find the association of the thrombophilia with RPL and the use of anticoagulation in preventing RPL and treatment of the hypercoagulability. Use of enoxaparin and low dose aspirin early in pregnancy with history of recurrent pregnancy loss due to acquired thrombophilia have statically significant improvement in live pregnancy. Same cannot be said about unknown cause of the recurrent pregnancy loss. The proper investigation of the cause of RPL should be carried out. A proper meta-analysis is required to prove these results by forest plot.

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