The Author ensures that the research has been conducted responsibly and ethically with adherence to all relevant regulations. read more..
Department of Clinical and Molecular Medicine, Sapienza University of Rome, Italy
*Corresponding author:Leonarda Galiuto, Department of Clinical and Molecular Medicine, Sapienza University of Rome and Division of Cardiology, Sant’Andrea University Hospital, Rome, Italy
Submission: May 19, 2025Published: July 03, 2025
ISSN: 2639-0612 Volume9 Issue 2
Background: Takotsubo Syndrome (TTS) is an acute coronary syndrome, resembling acute myocardial
infarction, due to reversible microvascular constriction producing transient myocardial dysfunction.
It mainly affects post-menopausal women after stress, trauma, or mourning. TTS may be lethal and
recurrent despite complete medical therapy. For the first time, we propose a psychotherapeutic approach
to prevent recurrences of TTS.
Methods: Patients with recurrent TTS underwent psychodynamic psychotherapy according to Mutative
Psychoanalytic Process (MPP), a novel psychotherapeutic intervention aiming to induce an evolutionary
change in the patient’s mental processes. We report an example case.
esult: In this TTS patient treated by PMP, the model allowed an early identification of the personality
structure, as neurotic character, with consequent representation in the therapist’s mind of the distress and
defensive mechanisms of the patient. The therapist eluded the patient’s trial to establish a relationship
model well known to her, thus producing an effective evolutionary change in the patient’s mind. The
patient concluded a successful cycle of psychotherapeutic treatments and has remained free of cardiac
symptoms since.
Conclusion: This initial psychotherapeutic experience confirms the psychodynamic genesis of cardiac
pathology and opens a new frontier for studies in this area. Which personality profile is more likely
associated with TTS, if it can predispose to such cardiac syndrome, and if MPP is the ideal treatment for
these patients remains to be demonstrated in a larger study population.
Keywords: Tako-tsubo syndrome; Psychotherapy
Ph.D in Agriculture from Faculty of Agriculture, Tohoku University
Research Professor, PhD, Holistic Research Institute
Professor, Chief Doctor, Director of Department of Pediatric Surgery, Associate Director of Department of Surgery, Doctoral Supervisor Tongji hospital, Tongji medical college, Huazhong University of Science and Technology
Senior Research Engineer and Professor, Center for Refining and Petrochemicals, Research Institute, King Fahd University of Petroleum and Minerals (KFUPM), Dhahran, Saudi Arabia
Fellow of International Agency for Standards and Ratings (IASR), Edith Cowan University, Sarich Neuroscience Research Institute
Chancellor Emeritus / Professor Emeritus of Chemistry and Physics, University of Missouri–St. Louis
Ph.D in Science from the Federal University of Alagoas, UFAL, Brazil
Assistant Professor in College of Architecture, Art and Design
Interim Dean, College of Education and Health Sciences, Director of Biomechanics Laboratory, Sport Science Innovation Program, Bridgewater State University
Professor of numerous training courses in Family Medicine
Assistant Professor, Department of Electronics and Computer Science
Emeritus Professor of Physics, Kadir Has University, Turkey
Wenzhou Medical University, China
Fooyin University, Taiwan
Saglik Bilimleri University, Turkey
Vincent Pol University, Poland
National Defence University of Malaysia, Malaysia
Dogus University, Turkey
Hope College, USA
Russian Academy of Sciences, Russia
Southern Cross University, Australia
Umm Al-Qura University, Saudi Arabia
City University of New York, USA
Khalifa University of Science & Technology, United Arab Emirates
Prince of Songkla University, Thailand
Hebei Normal University, China
Alexandria University, Egypt
Indian Institute of Technology Kharagpur, India
Council for Agriculture Research and Analysis of Agri Economy (CREA), Italy
King Fahd University of Petroleum and Minerals, Saudi Arabia
Universiti Teknologi MARA, Malaysia
King Abdulaziz University, Saudi Arabia
University of Oregon, USA
University of Edinburgh, Scotland
University of Tennessee, USA
Central University of Venezuela, Venezuela
Islamic Azad University Central Tehran Branch, Iran
Tourin University, Italy
Teaching & Public Speaking, Spain
Paeditric Hospital "Giovanni XXIII", Italy
General Chemical State Laboratory , Greece
University of Nicosia, Cyprus
Universidad Miguel Hernández de Elche, Spain
Oral Roberts University, USA
Beijing Normal University, China
Howard University, USA
Edith Cowan University, Australia
Dubai Health Authority, UAE
University of Minnesota, USA
Indian Institute of Technology Kharagpur, India
Serhal Hospital, Lebanon
University of Missouri-St. Louis , USA
University of Malta, Malta
National Center for Global Health and Medicine, Japan
Molloy College, USA
Federal University of Piauí, Brazil
Krankenhaus Nordwest Hospital, Germany
Belgorod State University, Russia
Laval University, Canada
Cinvestav-Unidad Saltillo, Mexico
UPMC Hamot Neuroscience Institute, USA
Ramon Llull University, Spain
White Bear Associates, LLC, USA
Lehigh University, USA
California Southern University, USA
Institute of Solid State Physics of RAS, Russia
University of Buenos Aires, Argentina
Mansoura University, Egypt
King Saud University, Saudi Arabia
University of Coimbra, Portugal