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Abstract

Novel Approaches in Cancer Study

Changing Landscape of Cholangiocarcinoma

Submission: March 02, 2020 Published: March 06, 2020

DOI: 10.31031/NACS.2020.04.000584

ISSN:2637-773X
Volume4 Issue2

Abstract

Cholangiocarcinoma occur in cholangiocytes, either in the intrahepatic, peri-hilar or distal bile duct locations. The three, command distinct attention due to difference in presentation and management. The current 5 years survival for localized intrahepatic cholangiocarcinoma is estimated to be at 24%. With the advent of molecular diagnostics and targeted therapy the field has seen some changes. Surgical resection is still the mainstay of therapy, although transplantation has been proposed in selected patients that have shown disease stability. Localized therapy for intra-hepatic and hilar tumors with neoadjuvant chemotherapy has also been used with some success for smaller tumors.

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