Abstract

Chronic diseases such as diabetes, cardiovascular disorders, neurodegenerative diseases, and autoimmune conditions are escalating globally and pose substantial clinical and economic burdens. Traditional pharmacological interventions have achieved varying degrees of symptomatic relief, yet many fail to halt or reverse underlying pathophysiological processes. Recent advances in biophoton therapy, a non-invasive modality that delivers coherent, low-intensity electromagnetic energy, suggest its potential to complement pharmacological treatments. This review examines the scientific basis, mechanisms of action, and clinical implications of combining biophoton therapy with conventional drugs. Emerging evidence highlights how biophoton therapy may enhance mitochondrial bioenergetics, restore redox balance, modulate immune responses, and improve microcirculation. When paired with pharmaceuticals, this synergistic approach can enhance drug absorption, reduce side effects, and amplify therapeutic efficacy. This review proposes a new paradigm for chronic disease management by integrating energetic and biochemical therapeutics.

Keywords: Biophoton therapy; Photobiomodulation; Chronic disease management; Mitochondrial bioenergetics; Integrative medicine; Pharmacological synergy