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1NN Petrov Research medical center of oncology, Saint-Petersburg, Russia
2II Mechnikov North-Western State Medical University, Saint-Petersburg, Russia
*Corresponding author:Bakhidze E, NN Petrov Research medical center of oncology, Saint-Petersburg, Russia
Submission: January 22, 2020Published: April 15, 2020
ISSN: 2577-2015Volume3 Issue4
Ovarian granulosa cell tumors (GCT) are rare ovarian neoplasms. The main treatment for GCT is surgical. The volume of operation depends on the stage of the disease and the age of the patient. The possibility of maintaining fertility in patients of reproductive age in the early stages of the disease and the feasibility of lymphadenectomy are discussed. The positive effect of repeated cytoreductive operations for relapse was demonstrated. Role of chemotherapy in the treatment of GCT, due to the rarity of GCT and the late recurrence of the disease, is still not defined. Adjuvant chemotherapy is not shown to protect against relapse in patients with adult type (AGCT). Hormone therapy is considered to be a promising direction for the palliative treatment of AGCT relapses.
Keywords: Granulosa cell tumors; Relapse; Surgical treatment; Fertility-saving treatment; Chemotherapy; Hormone therapy; Aromatase inhibitors
Ph.D in Agriculture from Faculty of Agriculture, Tohoku University
Research Professor, PhD, Holistic Research Institute
Professor, Chief Doctor, Director of Department of Pediatric Surgery, Associate Director of Department of Surgery, Doctoral Supervisor Tongji hospital, Tongji medical college, Huazhong University of Science and Technology
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