Abstract

Gastric metastasis from breast cancer is a rare phenomenon in clinical practice, of which the disease features and natural course could be insidious and undistinguished from primary gastric carcinoma. We reported a 37-year-old female patient newly diagnosed as endocrine-dependent breast cancer with synchronous the diffuse thickness of stomach and extensive metastases in the peritoneum as well as bilateral ovaries. The endoscopic view demonstrated a sign of linitis plastic. Histopathological results from gastric biopsy showed molecular features in favor of breast origin, which could be the major source of antidiastole. The prognostic outcomes were heterogeneous among patients with receipt of sequential therapy, where the molecular mechanisms remained to be elucidated.