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Abstract

Gastroenterology Medicine & Research

Anti-CTLA-4 Induced Inflammatory Bowel Disease: Is There A More Etiological Treatment? Lessons From CTLA-4 Haploinsufficiency

  • Open or Close Athina Theocharidou and Georgios Germanidis*

    First Department of Internal Medicine, Gastroenterology and Hepatology Section, AHEPA Hospital of the Aristotle University Medical School, Thessaloniki, Greece

    *Corresponding author: Georgios Germanidis, First Department of Internal Medicine, Gastroenterology and Hepatology Section,AHEPA Hospital of the Aristotle University Medical School,1, St. Kyriakidi Str., 546 36 Thessaloniki, Greece

Submission: May 10, 2018 ; Published: July 05, 2018

DOI: 10.31031/GMR.2018.01.000525

ISSN 2637-7632
Volume1 Issue5

Abstract

We read with great interest the article by Bamias G et al. [1] entitled “Immunological Characteristics of Colitis Associated with Anti-CTLA-4 Antibody Therapy’’ [1], and we would like to address some issues regarding possible future use of a more etiological treatment for this colitis, namely abatacept. The immunological characteristics of anti-CTLA-4 and anti-PD-1-related colitis have been up to now poorly described [1,2].

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