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Abstract

Gastroenterology Medicine & Research

Celiac Disease and “Idiopathic” Portal Hypertension: A Case Report and Review of Literature

Submission: August 24, 2017; Published: December 15, 2017

DOI: 10.31031/GMR.2017.01.000504

ISSN 2637-7632
Volume1 Issue1

Abstract

Idiopathic Portal hypertension (IPH) is a disorder of unknown etiology. We are reporting a case of IPH and Celiac disease. A 39-year old female patient was referred to gastroenterology clinic for diagnostic work-up of severe pancytopenia, massive splenomegaly and tense ascites. Diagnosis of IPH was clinically suspected after exclusion of possible causes that can manifest as portal hypertension. Endoscopy revealed esophageal varices along with atrophic folds and scalloping in the second part of the duodenum. Celiac disease was diagnosed based on histopathology findings and strong serology positivity for anti- tissue transglutaminase IgA. Her symptoms improved on a gluten-free diet and laboratory tests results improved considerably with significant reduction of the spleen size and ascites.

Conclusion: We suggest that physicians should be aware of this unusual association between celiac disease and IPH. Early diagnosis and proper treatment of Celiac disease not only helps to obviate the need for further unwarranted invasive procedures but also helped in improvement of portal hypertension.

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