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Abstract

Global Journal of Endocrinological Metabolism

Painless but not Harmless: Paradoxical Hypokalemia in Thyrotoxic Periodic Paralysis Due to Thyroiditis

  • Keshav Kataruka1 and Debmalya Sanyal2*

    1Department of Medicine, NHRTIICS, India

    2Department of Endocrinology, NHRTIICS and KPC Medical College, India

    *Corresponding author: Debmalya Sanyal, Department of Endocrinology, NHRTIICS and KPC Medical College, India

Submission: September 24, 2025; Published: October 16, 2025

DOI: 10.31031/GJEM.2025.03.000576

ISSN 2637-8019
Volume3 Issue5

Abstract

Background: Background: Thyrotoxic Periodic Paralysis (TPP) is a rare but life-threatening complication of thyrotoxicosis, characterized by recurrent episodes of muscle weakness associated with hypokalemia. Although Graves’ disease is the most common cause, thyroiditis is an unusual etiology.
Case: We report a 20-year-old male who presented with acute flaccid quadriparesis. Investigations revealed hypokalemia, suppressed TSH with elevated free T4, positive thyroid autoantibodies and reduced radionuclide uptake suggestive of thyroiditis. He improved with potassium replacement and β-blockers.
Conclusion: This case highlights the importance of thyroid function testing in all patients presenting with hypokalemic paralysis, as silent thyroiditis may rarely present as TPP.

Keywords:Catecholamines; Iymphocytic infiltration; Thyroid radionuclide; Normokalemic; Diplopia

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