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Abstract

Experimental Techniques in Urology & Nephrology

Renal resistive index in mouse model

  • Open or Close Zejun Ma1, Shan Lu2, Lexi Ding3 and Qiulun Lu4*

    1Key Laboratory of Hormones and Development (Ministry of Health), Tianjin Medical University, China

    2Department of Pharmacology, University of California, USA

    3Department of Ophthalmology, Xiangya Hospital, Center South University, China

    4Key Laboratory of Molecular Biophysics of the Ministry of Education, Huazhong University of Science and Technology, China

    *Corresponding author: Qiulun Lu, Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology and Center for Human Genome Research, Huazhong University of Science and Technology, Wuhan, China

Submission: January 20, 2018; Published: March 29, 2018

DOI: 10.31031/ETUN.2018.01.000522

ISSN: 2578-0395
Volume1 Issue5

Abstract

Renal Resistive Index (RI) analysis by Doppler ultrasonography has been shown to be associated with renal injury in clinics. Additionally, renal RI was applied on animals including rabbit, rat, and mouse in researches, which shows renal RI could also reflect the degree of renal impairment. There are two different methods for renal RI analysis in mouse model currently. One of them is widely performed as intrarenal RI, while the other is suprarenal RI. In this review, the difference of these two methods will discussed in depth, and their advantages and disadvantages will be described.

Keywords: Ultrasonography; Intrarenal RI; Suprarenal RI; Renal injury

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