Determinations in Nanomedicine & Nanotechnology

Chitin-Lignin Complex as New Green Tissue-Carrier for Innovative Pro- Aging Cosme-Nutraceuticals

Pierfrancesco Morganti^1,2*

¹China Medical University, China

²Director of R&D Center, Nanotechnology Unit, Academy of History of Healthcare Art, Italy

*Corresponding author:Pierfrancesco Morganti, China Medical University, Shenyang, China and Director of R&D Center, Nanotechnology Unit, Academy of History of Healthcare Art, Rome, Italy

Submission: July 16, 2025;Published: September 18, 2025

DOI: 10.31031/DNN.2025.03.000567

ISSN: 2832-4439
Volume3 Issue 4

Chitin and Lignin are both natural polymers made from crustaceans and tree structures respectively [1-4]. They are biodegradable chemical complex-compounds that, recovered by the natural sources may be used to produce green carriers and products, according to the circular economy (Figure 1 & 2). These innovative complexes have the ability to entrap into their structure’s different active ingredients, both hydro and liposoluble, for making new products, human and eco-friendly, used as Medical Devices, Cosmeceuticals or nutraceuticals [5-10]. Naturally when the used ingredient is characterized by a micro and nano-dimension, both activity and effectiveness of the realized products result notably increased [5-7]. However, it is interesting to underline the possibility to entrap natural ingredients into the Chitin- Lignin complexes (CLc) for making biodegradable fibers and tissue-carriers characterized as new drugs, nutraceuticals or cosmeceuticals, according to the ingredients used and selected by their biological and physicochemical characteristics [7,10-12]. According to our previous papers, the entrapment may be done mixing together the solutions of chitin nanofibrils nano lignin electrospinning the obtained gel with the selected polymeric by the electrospinning technology. The obtained specialized tissues personalized may be used as innovative carriers, alternative to emulsions, gel ad powders [2,5,13]. Naturally the tissues may be personalized by the use of selected ingredients for obtained innovative Cosmeceuticals and/or nutraceuticals that may controlled in vitro and in vivo to verify effectiveness and safeness. Therefore, they may be considered new green structures because made by natural ingredients 100%biodegradable and hypoallergenic because free from water, emulsifiers, preservatives, fragrances and other chemicals, often cause of allergic and sensitizing phenomena [2,5,13,14]. Moreover, these new tissue-carriers could be useful to produce, for example, innovative pro-aging products, having shown to be free from side effects and to be able to increase skin penetration of the selected active ingredients entrapped into their fibers, in a better way, when compared to the usual emulsions [15]. The efficacy of any ingredients, in fact, has been determined not only for their own effectiveness, but also for the capacity shown regarding the penetration through the skin layers and the skin annexes [15].

Figure 1:Chitin source and recovery [3].

Figure 2:Lignin source and recovery [4].

Natural polymers, such as Chitin and Lignin, specifically at their micro/nano dimension represent a new area of Research of great interest. The nano dimension, in fact, can show atomic-like behaviours characterized by a higher surface compared to the bulk materials [16,17]. Due to their morphology and physicochemical characteristics, the Chitin-lignin nanoparticles seem to result a new carrier to make innovative products. It is interesting to underline that both the polymers are 100% biodegradable and obtainable at low cost and with a low consume of water and energy as well as the electrospinning necessary to produce the reported healthy tissues and bio-eco-compatible products [5-7,18-20]. Moreover, both the two polymers are not only useful as an innovative carrier but could represent source of active ingredients, when degraded by the skin enzymes.

Idea of manuscript, writing-original draft preparation a review, editing and supervision Pierfrancesco Morganti. The author declare that have read it and agree to the publishing version.