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Abstract

Determinations in Nanomedicine & Nanotechnology

Effect of Pregnancy on Oxidative Status of Sheep

Submission: January 09, 2023;Published: February 10, 2023

Abstract

The objective of the study was to determine the effects of pregnancy on oxidative status of sheep Specific goal of the study was to determine the impact of pregnancy on serum concentration of antioxidant enzymes and the level of lipid peroxidation. Two groups of sheep (10) consisting of pregnant and non-pregnant ewes were used for the study. The pregnant ewes were at third trimester of pregnancy which was confirmed by abdominal palpation and serum progesterone level above 2.2ng/ml. Serum levels of catalase, superoxide dismutase, glutathione peroxidase enzymes and malondealdehyde were determined. The results indicated similar (p>0.05) mean values of serum concentration of catalase, superoxide dismutase and glutathione peroxidase. The serum level of malondealdehyde was significantly higher in pregnant ewes compared to non-pregnant animals. It can be concluded that the third trimester of pregnancy is associated with higher serum levels of malondealdehyde.

Keywords:Ewes; Pregnancy; Oxidative stress; Antioxidant enzymes; Antioxidant status

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