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Abstract
Advancements in Bioequivalence & Bioavailability
Crystal Engineering Applied to the Development of Novel Pharmaceutical Solid Forms with Improved Bioavailability: the Co Crystals Case
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Open or Close Luan F Diniz, Matheus S Souza and Javier Ellena*
Laboratory of Structural Crystallography Multiuser Laboratory, University of São Paulo, Brazil
*Corresponding author: Javier Ellena, Multiuser Laboratory of Structural Crystallography, Institute of Physics of São Carlos, University of São Paulo, Av. Trabalhador São-Carlense 400, Pq Arnold Schimidt CP 369, 13.560-970 - São Carlos, SP, Brazil
Submission: March 14, 2018; Published: June 08, 2018
ISSN 2640-9275 Volume1 Issue3
Abstract
Pharmaceutical co crystal technology has emerged as a promising strategy to enhance bioavailability of poorly water soluble drugs. This mini review presents a brief overview of pharmaceutical co crystals with particular focus on co crystal design, characterization techniques and impacts on drug bioavailability.
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