Abstract

Cyclodextrin are useful functional excipients that have enjoyed widespread attention and use. The basis for this popularity from a pharmaceutical standpoint is the ability of these materials to interact with poorly water-soluble drugs and drug candidates water solubility. β-cyclodextrins have a wide range of applications in different areas of drug delivery and pharmaceutical industry due to their complexation ability and other versatile characteristics. β-cyclodextrin (βCD) contains 7 glucopyranose units and is the most commonly used cyclodextrin polymer. They are known to form inclusion complexes with poorly soluble drugs and to improve their bioavailability and enhance their solubility. The objective of this review is to summarize general properties and different uses of βCD, and recent advancements related to its application.

Keywords:Cyclodextrin; Drugs; Glucose; βCD molecule; Antioxidants