Pregnancy associated with acute pancreatitis is a potentially life-threatening but rare event occurring in approximately three in 10000 pregnancies. Its prompt diagnosis warrants a high degree of suspicion in women who present with severe upper abdominal pain which may or may not radiate to the back. These patients usually have accompanying anorexia, nausea and vomiting. Serum amylase, lipase, CRP and abdominal ultrasound should be included in the initial workup for these symptoms occurring during pregnancy. It occurs usually during the third trimester or the early postpartum period. Once the diagnosis of acute pancreatitis is established, the mainstay of treatment is symptomatic including aggressive fluid resuscitation if not otherwise contraindicated and pain relief; antibiotics should not be initiated at this stage. Next it would be imperative to ascertain the severity of the disease using established criteria such as the modified Glasgow or Atlanta’s criteria within the first 48 hours of admission.