The Author ensures that the research has been conducted responsibly and ethically with adherence to all relevant regulations. read more..
Neurosurgery Department, Neuroplasticity and Glial Tumors Laboratory, Algeria
*Corresponding author: Bouaita K, Neurosurgery Department, Neuroplasticity and Glial Tumors Laboratory, Algeria
Submission:October 25, 2021;Published: January 17, 2022
ISSN : 2578-0379Volume4 Issue4
The purpose: The management of intracranial ependymomas represents a real challenge and the perfect treatment modality remains controversed. The goal of this study is to highlight the role of tumour removal and the adjuvant therapy in the survival rate of children presenting with intracranial ependymomas. Patients and methods: This retrospective study of 56 children presenting with non-metastatic intracranial ependymomas treated in the period between 2015 and 2020. The age varies from 3 months to 15 years while the mean age was 8 years. The infra tentorial location was found in 67.8%. Result: The total resection of the tumour was achieved in only 42.8% of cases, whereas the subtotal resection was performed in 35.7%. More than 50% of tumours were grade I and II of the Who classification (grade I: 12 cases, grade II: 18 cases). 44.6% were anaplasique ependymomas (grade III: 25 cases). More than half of our cases had initial adjuvant radiotherapy (55.3%) and 21.4% had chemotherapy. 4 children had both radiotherapy and chemotherapy. Complications that were found in our serie were 6 cases of CSF fistula in the origin of 4 cases of meningitis, 9 cases of neurological deterioration with 2 cases of postoperative seizures and 2 other cases of intra ventricular haemorrhage. The mortality rate after 38 months was 7.1% (4 cases). The Follow-up length was 5 years. Conclusion: The role of surgery and the extent of resection in the intracranial ependymomas in children remains the most important factor in the global management of this type of intracranial tumour. adjuvant radiotherapy helps achieving a survival rate for the anaplastic types and recurrences.
Keywords: Anaplastic ependymomas; Ependymomas; Radiotherapy
Ph.D in Agriculture from Faculty of Agriculture, Tohoku University
Research Professor, PhD, Holistic Research Institute
Professor, Chief Doctor, Director of Department of Pediatric Surgery, Associate Director of Department of Surgery, Doctoral Supervisor Tongji hospital, Tongji medical college, Huazhong University of Science and Technology
Senior Research Engineer and Professor, Center for Refining and Petrochemicals, Research Institute, King Fahd University of Petroleum and Minerals (KFUPM), Dhahran, Saudi Arabia
Fellow of International Agency for Standards and Ratings (IASR), Edith Cowan University, Sarich Neuroscience Research Institute
Chancellor Emeritus / Professor Emeritus of Chemistry and Physics, University of Missouri–St. Louis
Ph.D in Science from the Federal University of Alagoas, UFAL, Brazil
Assistant Professor in College of Architecture, Art and Design
Interim Dean, College of Education and Health Sciences, Director of Biomechanics Laboratory, Sport Science Innovation Program, Bridgewater State University
Professor of numerous training courses in Family Medicine
Assistant Professor, Department of Electronics and Computer Science
Emeritus Professor of Physics, Kadir Has University, Turkey
Wenzhou Medical University, China
Fooyin University, Taiwan
Saglik Bilimleri University, Turkey
Vincent Pol University, Poland
National Defence University of Malaysia, Malaysia
Dogus University, Turkey
Hope College, USA
Russian Academy of Sciences, Russia
Southern Cross University, Australia
Umm Al-Qura University, Saudi Arabia
City University of New York, USA
Khalifa University of Science & Technology, United Arab Emirates
Hebei Normal University, China
Alexandria University, Egypt
Indian Institute of Technology Kharagpur, India
Council for Agriculture Research and Analysis of Agri Economy (CREA), Italy
King Fahd University of Petroleum and Minerals, Saudi Arabia
King Abdulaziz University, Saudi Arabia
University of Oregon, USA
University of Edinburgh, Scotland
University of Tennessee, USA
Central University of Venezuela, Venezuela
Islamic Azad University Central Tehran Branch, Iran
Tourin University, Italy
Teaching & Public Speaking, Spain
Paeditric Hospital "Giovanni XXIII", Italy
University of Nicosia, Cyprus
Universidad Miguel Hernández de Elche, Spain
Oral Roberts University, USA
Beijing Normal University, China
Howard University, USA
Edith Cowan University, Australia
Dubai Health Authority, UAE
University of Minnesota, USA
Indian Institute of Technology Kharagpur, India
Serhal Hospital, Lebanon
University of Malta, Malta
National Center for Global Health and Medicine, Japan
Molloy College, USA
Federal University of Piauí, Brazil
Krankenhaus Nordwest Hospital, Germany
Belgorod State University, Russia
Laval University, Canada
Cinvestav-Unidad Saltillo, Mexico
UPMC Hamot Neuroscience Institute, USA
Ramon Llull University, Spain
White Bear Associates, LLC, USA
Lehigh University, USA
California Southern University, USA
Institute of Solid State Physics of RAS, Russia
University of Buenos Aires, Argentina
Mansoura University, Egypt
King Saud University, Saudi Arabia
University of Coimbra, Portugal