Crimson Publishers Publish With Us Reprints e-Books Video articles

Abstract

Research in Medical & Engineering Sciences

Dynamic Freedom: Substrate Stress Relaxation Stimulates Cell Responses

Submission: September 02, 2018; Published: November 27, 2018

DOI: 10.31031/RMES.2018.07.000652

ISSN: 2576-8816
Volume7 Issue1

Abstract

Natural tissues comprise a population of cells, extra cellular matrix (ECM) and signaling biomolecules. The only living component, cell, interacts with each other and with the ECM in an incredibly multifaceted way. From the materials point of view, cells are highly dynamic viscoelastic materials; reside in highly dynamic three dimensional (3D) viscoelastic ECM, communicate with its surrounding in a highly dynamic and complex way, and form a highly dynamic viscoelastic tissue [1,2]. The cells can continually read the microenviromental cues such as stiffness, porosity, topography etc. and respond to them in a mechano-sensitive way to maintain the both cellular and tissue health [3]. It has been long recognized that matrix integrity or stiffness has profound influences on cell function and fate [4-7].

Get access to the full text of this article


About Crimson

We at Crimson Publishing are a group of people with a combined passion for science and research, who wants to bring to the world a unified platform where all scientific know-how is available read more...

Leave a comment

Contact Info

  • Crimson Publishers, LLC
  • 555 Madison Avenue, 5th floor
  •     New York, NY 10022, USA
  • +1 (929) 600-8049
  • +1 (929) 447-1137
  • info@crimsonpublishers.com
  • www.crimsonpublishers.com