1General University Hospital of Patras-All Holy Theotokos the Helper, Greece
2Nursing Department, University of Patras, Greece
*Corresponding author:Anastasios Tzenalis, Associate Professor in ICU, Nursing Department, University of Patras, Greece
Submission: March 7, 2025;Published: March 20, 2025
ISSN: 2578-0204Volume4 Issue 5
Introduction: In-Hospital Cardiac Arrest (IHCA) is a critical emergency that occurs unpredictably and
is associated with high morbidity and mortality rates. Nurses play a crucial role as first responders in
managing, especially when it comes to the administration of medications such as epinephrine and
amiodarone, which are essential for restoring circulation and managing life-threatening arrhythmias.
The effectiveness of these medications is dependent on early and correct administration in line with
Advanced Life Support (ALS) guidelines. This study aims to assess nurses’ knowledge of pharmacological
interventions in IHCA and the impact of this knowledge on patient outcomes.
Methods: This study was conducted in a hospital setting, involving nursing staff from various
departments. Data were collected using an electronic questionnaire, with the responses analyzed using
IBM SPSS Statistics 22.0 software. To describe the quantitative variables, central tendency and spreading
focus methods were used. Categorical variables were described through frequency tables. To assess the
correlation between categorical variables, chi-square and Fisher tests were used and 95% confidence
intervals were calculated.
Results: The findings indicated a significant correlation between nurses’ education on ALS protocols and
their knowledge of drug administration during IHCA. Nurses with formal training in Basic Life Support
(BLS), Immediate Life Support (ILS), and Advanced Life Support (ALS) showed improved understanding
of medication administration, resulting in better adherence to guidelines during resuscitation.
Discussion: The study underscores the importance of continuous education and training for nurses to
ensure adherence to ALS guidelines. Regular participation in certified courses, such as BLS, ILS, and ALS,
is recommended to enhance nurses’ ability to manage cardiopulmonary arrest effectively. This research
highlights the need for standardized training programs to improve outcomes in IHCA.
Keywords:Nurses’ knowledge; Cardiac arrest drugs; IHCA; BLS; ILS; ALS; Cardiopulmonary resuscitation
Abbreviations:BLS: Basic Life Support; CPR: Cardiopulmonary Resuscitation; ACLS: Advanced Cardiac Life Support; ILS: Immediate Life Support; ALS: Advanced Life Support