Abstracts

Acute myocardial infarction (AMI) occurs when blood flow is occulted by an atherosclerotic plaque prevent in the intima lining of a coronary artery. 50 patients with diagnostic features of AMI were recruited and constituted the study group and 25 healthy age and sex matched controls were recruited for comparison constituted the control group. Special investigations such as CPK-MB, Troponin-I and other routine investigation were assayed. We concluded from the results that whenever considering the role of cardiac Troponin-I and CPK-MB in the diagnosis of AMI, we required both CPK-MB and Troponin-I for the diagnosis of AMI. Troponin-I rises within 6 hours of chest pain, remains raised for 10 days and CPK-MB is raised within 6-12 hours of chest pain and comes back to normal levels within 48 hours. So, we can say that fresh attack will be assayed by serial CPK-MB whereas Troponin-I will not be able to indicate the fresh infarction, but Troponin-I is a better indicator of AMI.

Keywords: Acute myocardium infarction; CPK; Troponin I