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Modern Research in Dentistry

Evaluating The Effects of Probiotics After SRP on Generalized Moderate to Severe Chronic Periodontitis - A Randomized Clinical Trial

Submission: December 20, 2021Published: July 29, 2022

DOI: 10.31031/MRD.2022.07.000664

Volume7 Issue2


Aim: Periodontitis is the inflammation of teeth surrounding tissues caused irreversibly by infection. Oral hygiene education, Scaling and Root Planning (SRP), antibiotics and surgical procedures are the existing treatment methods. However, they are not long-lasting. Therefore, we aimed to evaluate the effect of probiotic administration as mouthwash after SRP on periodontal condition in patients with generalized moderate to severe chronic periodontitis. Materials and methods: In this study which was a double-blinded randomized clinical trial, 51 eligible patients with generalized moderate to severe chronic periodontitis who were referred to Mashhad Faculty of dentistry, were randomly allocated to test (SRP+ probiotics (FamiLact, n=26)) or control (SRP+placebo (n=25)) group. All the subjects were instructed to use the capsules as mouthwash once a day for 20 days. At the initial phase of the study, we used Clinical Attachment Loss (CAL) for determination of generalized moderate to severe chronic periodontitis. Afterwards, we employed Bleeding on Probing (BOP) and Pocket Probing Depth (PPD) at baseline and after 20-day course of treatment. Results: After the baseline treatments and 20-day period of administration of capsules, the test group demonstrated a 34.7% reduction in BOP index and a 28.76% reduction was observed in the control group (P-value=0.001, difference=6%). The test group also showed a 1.68mm reduction in PPD index which was significantly higher than that of the control group with 0.88mm reduction (P-value=0.0001, difference=0.79mm). Conclusion: According to the results of our study and significant difference of parameters improvement between the test and control groups, it is concluded that topical administration of probiotics after SRP can help decrease periodontal inflammation in the short-term..

Keywords: Chronic periodontitis; Gingiva; Probiotic; Scaling and root planning; Oral health; Mouthwash

Abbreviations:SRP: Scaling and Root Planning; CAL: Clinical Attachment Loss; BOP: Bleeding on Probing; PPD: Pocket Probing Depth; GI: Gingival Index; PI: Plaque Index; BI: Bleeding Index; MGI: Modified Gingival Index; CAG: Clinical Attachment Gain; GBI: Gingival Bleeding Index

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