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University of Niš, Faculty of Electronic Engineering, Serbia
*Corresponding author: Dušica P Ilić, University of Niš, Faculty of Electronic Engineering, Aleksandra Medvedeva 14, 18115 Niš, Serbia
Submission: May 25, 2022; Published: June 29, 2022
ISSN: 2637-7802Volume7 Issue2
This work is devoted to scientific research carried out to investigate the content of cranberry fruits (Vaccinium macrocarpon L., Ericaceae). To evaluate the influence of composition on anti-inflammatory activity, cranberry fruits were collected from eight Serbia growing regions. Eight extracts from these fruits were prepared. Extracts were analyzed for phytochemical composition and evaluated for their anti-inflammatory effects in human monocytes (THP-1 cells). All were able to reduce Lipopolysaccharide (LPS) -induced production of pro-inflammatory cytokine interleukin 6 (IL-6) at 50μg/mL, with inhibition ranging between 10.09-42.7%. The research results show phytochemicals present in varying quantities in cranberry fruits a role in the anti-inflammatory effects of cranberry extracts on human monocytes.
Keywords:Cranberry; Anti-inflammatory; Antioxidant; Cytokines; Polyphenols; Phytochemicals; Monocytes
Ph.D in Agriculture from Faculty of Agriculture, Tohoku University
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