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Advances in Complementary & Alternative medicine

Hypoparathyroidism Associated with Plaque Psoriasis-A Case Report

  • Open or CloseAlireza Rezayi1, Shadab Salehpour2, Fatemeh Kodaei1* and Maryam Saberi1

    1Skull Base Research Center, Shahid Beheshti University of Medical Sciences, Iran

    2Department of Pediatric Endocrinology and Metabolism, Shahid Beheshti University of Medical Sciences, Iran

    *Corresponding author: Fatemeh Khodaei, Skull Base Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Iran

Submission: March 12, 2021; Published: March 30, 2021

DOI: 10.31031/ACAM.2021.06.000639

ISSN: 2637-7802
Volume6 Issue3


A 17-year-old Afghani male is described with hypoparathyroidism and plaque psoriasis associated with multiple intracranial calcifications. A diagnosis of hypoparathyroidism was made based on hypocalcaemia, hyperphosphatemia and low PTH level. A skin biopsy was compatible histopatholigically with psoriasis. He mentioned a listed problem consisted of frequent paroxysmal spells of generalized tonic-clonic seizures during the past ten years and a history of suffering from tingling and numbness of the extremities especially localized at the lower limbs, during the recent years. Also, he had frequently spontaneous episodes of invasive behaviors happened during the recent years seemed to be another manifestation of hypocalcemia due to hypoparathyroidism. Considerably, he had an unsuccessful history of phenobarbital therapy during the past years. At admission, positive trousseau and chvostek signs besides a prolonged QT interval obtained on ECG, revealed hypocalcemia, and confirmed by low serum calcium level. After initial treatment with calcium infusion, the maintenance therapy continued with calcium supplement and calcitriol. Surprisingly after serum calcium correction, the clinical condition improved, and the skin rash showed significant improvement.

Keywords: Hypoparathyroidism; Psoriasis; Hypocalcaemia; Intracranial calcifications

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