Ghassan George Haddad*
Le Boulevard Bldg 6th floor, Lebanon
*Corresponding author: Ghassan George Haddad, Le Boulevard Bldg 6th floor, Jdeidet El Metn, Lebanon
Submission: July 10, 2017; Published: November 13, 2017
Elsberg syndrome (ES) is an infectious syndrome consisting of acute bilateral lumbosacral radiculitis, often accompanied by myelitis confined to the lower spinal cord, and is frequently a manifestation of reactivation, or occasionally, primary herpes simplex virus 2 infection .
The onset of ES is consistently acute and symptoms includes: Urinary retention, urinary incontinence, bowel incontinence, saddle anesthesia, exaggerated/pathologic lower limb tendon reflexes or absent lower limb tendon reflexes, Loss of limb sensation and Leg weakness .
Clinical picture, MRI, EMG and CSF studies confirm the diagnosis.
EMG shows evidence of radiculopathies.
MRI of the Spinal cord lesions (Figure 1) shows multiple, discontinuous, and centrally or ventrally positioned lesions generally sparing the distal conus. Nerve root enhancement is prominent and smooth rather than nodular  shows Lymphocytic CSF pleocytosis CSF proteins were consistently elevated, and oligoclonal bands are rarely detected. CSF PCR is positive for VZV and 43% of cases have viral isolation studies positive for herpes.
Figure 1: Picture A enhancement of the nerve roots.
Picture B shows the presence of multiple and discontinuous T2 hyperintense lesions in the caudal spinal cord.Picture
C shows enhancement of the nerve roots of the cauda equine.
I. Lymphoma, Spinal neoplasms, Vascular disorders (dural arteriovenous fistula).
II. Guillain-Barre'syndrome, chronic inflammatory demyelinating, polyneuropathy, MS, NMO or clinically isolated demyelinating syndrome.
III. Myelitis secondary to systemic autoimmune diseases (sarcoidosis, SLE, Sjögren, Behcet, and systemic sclerosis).
a. viral (not herpes), bacterial, fungal, lyme or parasitic.
b. Infectious brain infection (encephalitis or meningitis)
c. Paraneoplastic myelitis
d. Motor neuron disease References
e. Radiation myelopathy
f. Metabolic myelopathy (vitamins B12, D, E, and copper deficiencies)
Acyclovir is the treatment of choice and most patients recover with sequelae.
© 2017 Ghassan George Haddad. This is an open access article distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and build upon your work non-commercially.