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Abstract

Surgical Medicine Open Access Journal

Can Next Generation Genomics be Used to Predict the Outcome of Total Joint Arthroplasty

  • Open or CloseNivbrant NO1, Wood D2*, Koks S3

    1Fiona Stanley Hospital, Australia

    2Fiona Stanley Hospital, Australia

    3Fiona Stanley Hospital, Australia

    *Corresponding author:Wood David, University of Western Australia, 35 Stirling Hwy, Crawley WA 6009, Australia

Submission:November 23, 2021;Published: December 08, 202

DOI: 10.31031/SMOAJ.2021.04.000593

ISSN : 2578-0379
Volume4 Issue4

Abstract

Keywords:Genomics; Arthroplasty; Orthopaedic; Implant Surgery; Pathological; Musculoskeletal Conditions; Morbidity; Mortality; Genetics

Abbreviations: IFIT: Interferon Induced Genes; TJA: Total Joint Arthroplasty; TKA: Total Knee Arthroplasty; THA: Total Hip Arthroplasty; AL: Aseptic Loosening; UHMWPE: Ultra High Molecular Weight Polyethylene; DNA: Deoxyribo Nucleic Acid; PCR: Polymerase Chain Reaction; BLAST: Basic Local Alignment Search Tool; AIR: Adverse Immune Reaction; ROS: Reactive Oxygen Species; DAMPs: Damage- Associated Molecular Patterns; GWAS: Genome-Wide Association Study; PRS: Polygenic Risk Score

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