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Abstract

Significances of Bioengineering & Biosciences

Application of Metabolomics to Reveal the Biological Mechanism of Toxicological Research

  • Open or CloseTai Ping Li1, Wan Ying Wang2, Hui Dong1, Junling Ren1, Hui Sun1, Fang Fang Wu3, Ai Hua Zhang1 and Xi Jun Wang1,2,3*

    1National Chinmedomics Research Center, National TCM Key Laboratory of Serum Pharmacochemistry, China

    2State Key Laboratory of Quality Research in Chinese Medicine, China

    3National Engineering Laboratory for the Development of Southwestern Endangered Medicinal Materials, Guangxi Botanical Garden of Medicinal Plant, China

    *Corresponding author: Xi Jun Wang, National Chinmedomics Research Center, National TCM Key Laboratory of Serum Pharmacochemistry, Metabolomics Laboratory, Department of Pharmaceutical Analysis, Heilongjiang University of Chinese Medicine, Harbin, Chinan

Submission: November 09, 2020;Published: December 04, 2020

DOI: 10.31031/SBB.2020.04.000583

ISSN 2637-8078
Volume 4 Issue 2

Abstract

Metabolomics can illustrate microscopic changes in the metabolic mechanisms of toxicity caused by frequent exposure to drugs, herbs, and environmental pollutants, and recent reports have supported the great potential and value of metabolomics in reducing the occurrence of injury reactions.M/

Keywords: Metabolomics; Toxicology; Biomarkers; Metabolic pathways; MechanismsM/

Abbreviations: GC: Gas Chromatography; LC:Liquid Chromatography; MS: Mass Spectrometry; NMR:Nuclear Magnetic Resonance

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