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Significances of Bioengineering & Biosciences

Noncoding RNA Modulation for Cardiovascular Therapeutics

Submission: March 15, 2018;Published: April 03, 2018

DOI: 10.31031/SBB.2018.01.000513

ISSN 2637-8078
Volume1 Issue3


Cardiovascular diseasesare multifactorial diseases that involve alteration of multiple genes and subsequent phenotypic changes. Non-coding RNAs regulate gene expression, affecting many physiological and pathophysiological processes in humans. Accumulating evidence indicates that noncoding RNA, such as microRNAs, expression profile changes can lead to cardiovascular diseases. This article reviews the current findings regarding the roles of noncoding RNAs in cardiovascular diseases, and strategy to modulate them for therapeutics.

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