Abstract

The term “OEIS-complex” was introduced by Carey and colleagues to describe a group of malformations associated with cloacal exstrophy. These include: O - omphalocele, E - exstrophy, I - imperforate anus, and S-spinal deformities. Cloacal exstrophy, including the OEIS-complex, is typically diagnosed prenatally through modern imaging techniques, particularly ultrasound during the screening stage in antenatal care settings. This combined malformation generally has satisfactory treatment outcomes but requires multiple surgical interventions aimed at reconstructive surgery and restoring organ function. However, the long-term quality of life for patients is often compromised by severe disability, fecal incontinence due to functional disorders of the operated colon, and cognitive impairments. The extended duration of treatment, frequent surgical procedures, and the need for prolonged respiratory support in premature infants increase the risk of aspiration pneumonia, which is challenging to manage and can lead to sepsis and patient mortality. This article presents a clinical case of cloacal exstrophy in a premature infant complicated by aspiration pneumonia and sepsis.

Keywords: Cloacal exstrophy;OEIS -complex; Aspiration pneumonia; Sepsis

Abbreviations: OEIS: Omphalocele Exstrophy Imperforate Anus Spinal Deformities; CNS: Central Nervous System; SCT: Spiral Computed Tomography; MRI: Magnetic Resonance Imaging; SWI: Susceptibility Weighted Imaging