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Abstract

Research in Pediatrics & Neonatology

Giant Congenital Melanocytic Naevus: A Case Report and the Potential Risk Factor of Autoimmunity

  • Open or CloseHughes NJ*, Verma A and Chetan R

    Department of Paediatrics, Southend University Hospital NHS Foundation Trust, UK

    *Corresponding author: Hughes NJ, Department of Paediatrics, Southend University Hospital NHS Foundation Trust, UK

Submission: October 26, 2021; Published: December 01, 2021

ISSN : 2576-9200
Volume6 Issue2

Abstract

Background: GCMN is a rare condition associated with neurological abnormalities and risk of malignant transformation into potentially fatal tumours.

Case presentation: We report a case of profound GCMN in a newborn with a maternal background of autoimmune disease.

Conclusion: There may be an unexplored shared genetic basis between an abnormal immune milieu and risk of GCMN. Management of GCMN is multifactorial and patient-centred, with no evidence for definitive treatment at present.

Keywords: Neonatology; Dermatology; Congenital; Autoimmunity

Abbreviations: GCMN: Giant Congenital Melanocytic Naevus, MAPK: Microtubule-Associated Protein Kinase

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